Diabetology International
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Exploring the signal-dependent transcriptional regulation involved in the liver pathology of type 2 diabetes
Diabetology International - Tập 14 - Trang 15-20 - 2022
Excess glucagon activity in diabetes increases hepatic glucose production via gluconeogenic gene induction, thus exacerbating hyperglycemia. Glucagon receptor-activated cAMP-dependent protein kinase A (PKA) induces proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α) expression via the cAMP response element-binding protein (CREB)-regulated transcription coactivator 2 (CRTC2) pathway....... hiện toàn bộ
Serum lipid management in patients with type 1 and type 2 diabetes: a hospital-based cohort study
Diabetology International - Tập 10 - Trang 67-76 - 2018
Serum lipid management is important for patients with diabetes; however, it has not been examined in our specialized diabetes clinic. The aim of the study was to assess the percentage of patients who did not achieve management targets (MT) for low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C) and triglycerides (TG), and explore factors related to failure to ...... hiện toàn bộ
The diabetes quality of life brief clinical inventory in combination with the management strategies in type 1 diabetes mellitus with or without the use of insulin pump
Diabetology International - Tập 12 - Trang 217-228 - 2020
The aims of this study are to evaluate any differences in the Quality of life among Continuous Subcutaneous Insulin Infusion (CSII) and Multiple Dose Injection (MDI) insulin delivery, applying the Diabetes Quality of life Brief Clinical Inventory (DQoL-BCI) questionnaire, and assess the diabetes management strategies between the two groups. One hundred and ten adult participants (male/female ratio...... hiện toàn bộ
Periodontal diseases assessed by average bone resorption are associated with microvascular complications in patients with type 2 diabetes
Diabetology International - Tập 14 - Trang 32-39 - 2022
Periodontal disease often develops in patients with diabetes, and further exacerbated with diabetic complications. It would be clinically important to clarify the relationship between diabetic microvascular diseases and periodontal disease. This study aimed to evaluate the association between periodontal disease and diabetic complications in patients with type 2 diabetes with poor glycemic control...... hiện toàn bộ
Effectiveness of management protocol for insulin balls in diabetics: a scoping review
Diabetology International - - Trang 1-17 - 2023
In order to achieve good glycemic control, the prevention and management of insulin balls is important for diabetic patients during insulin therapy. However, insulin balls still occur within the clinical setting. This review evaluated the effectiveness of programs designed to manage insulin balls. A scoping review was conducted based on the Japanese and English literature available from a systemat...... hiện toàn bộ
A single-nucleotide polymorphism in the human THADA gene is associated with circulating resistin in the general Japanese population
Diabetology International - - 2011
Resistin, secreted from adipocytes, causes insulin resistance in mice. We previously reported that the G/G genotype of a single-nucleotide polymorphism (SNP)-420 (rs1862513) in the human resistin gene (RETN) resulted in an increase in circulating resistin and susceptibility to type 2 diabetes (T2D). Whereas PPARG Pro12Ala Pro/Pro and RETN SNP-420 G/G genotypes were synergistically associated with ...... hiện toàn bộ
Causes of death in Japanese people with type 2 diabetes and factors associated with all-cause mortality from a large registry in Japan: the Japan Diabetes Complication and its prevention prospective (JDCP) study-9
Diabetology International - Tập 14 - Trang 272-279 - 2023
We aimed to estimate the causes of death and their incidence rates and risk factors for all-cause mortality in Japanese people with type 2 diabetes using baseline data from the Japan Diabetes Complication and its Prevention (JDCP) prospective study. We analyzed a multicenter prospective cohort of 5944 Japanese people with diabetes aged 40–74 years. Causes of death were categorized as cardiac or ce...... hiện toàn bộ
Documented contraceptive use after delivery in women with pre-gestational and gestational diabetes in Thailand: a single center study
Diabetology International - - 2022
A diabetic patient in whom Hb Weesp was incidentally detected when her HbA1c level was measured
Diabetology International - Tập 10 Số 4 - Trang 300-302 - 2019
Laser treatment for lipoatrophy in children with diabetes type 1
Diabetology International - Tập 13 - Trang 452-455 - 2021
Lipoatrophy (LA) is one of the complications of insulin treatment. It has become rare thanks to insulin analogues but it can still be observed in patients with diabetes type 1(T1DM). No effective treatment exists. Herein, we report for the first time two children with T1DM and LA successfully treated with laser treatment. A 6-year-old child with T1DM presented with LA 4 months post-diagnosis. He w...... hiện toàn bộ
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