Diabetes

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Apoptosis Is the Mode of β-Cell Death Responsible for the Development of IDDM in the Nonobese Diabetic (NOD) Mouse
Diabetes - Tập 46 Số 5 - Trang 750-757 - 1997
Bronwyn A. O’Brien, Brian Harmon, Donald P. Cameron, David J. Allan
The NOD/Lt mouse, a widely used model of human autoimmune IDDM, was used to establish the mode of β-cell death responsible for the development of IDDM. Apoptotic cells were present within the islets of Langerhans in hematoxylin and eosin–stained sections of pancreases harvested from 3- to 18-week-old female NOD/Lt mice (a range of 11–50 apoptotic cells per 100 islets). Immunohistochemical localiza... hiện toàn bộ
Predicting Hypoglycemia Non-invasively in Type 1 Adolescent Diabetes Using the HypoMon
Diabetes - - Trang - 2006
Ghevondian, N, Nguyen, HT, Jones, TW, Siafarikas, A, Ratnam, N
#Conference Proceeding
Association of Variants in RETN With Plasma Resistin Levels and Diabetes-Related Traits in the Framingham Offspring Study
Diabetes - Tập 58 Số 3 - Trang 750-756 - 2009
Marie‐France Hivert, Man Li, Jarred B. McAteer, Josée Dupuis, Caroline S. Fox, L. Adrienne Cupples, James B. Meigs, Jose C. Florez
OBJECTIVE— The RETN gene encodes the adipokine resistin. Associations of RETN with plasma resistin levels, type 2 diabetes, and related metabolic traits have been inconsistent. Using comprehensive linkage disequilibrium mapping, we genotyped tag single nucleotide polymorphisms (SNPs) in RETN and tested associations with plasma resistin levels, risk of diabetes, and glycemic traits. RESEARCH DESIGN... hiện toàn bộ
Autoantibodies to protein tyrosine phosphatase-like proteins in type I diabetes. Overlapping specificities to phogrin and ICA512/IA-2
Diabetes - Tập 45 Số 10 - Trang 1344-1349 - 1996
E. Kawasaki, George S. Eisenbarth, C. Wasmeier, J. C. Hutton
HLA heterogeneity of insulin-dependent diabetes mellitus at diagnosis. The Pittsburgh IDDM study
Diabetes - Tập 34 Số 12 - Trang 1247-1252 - 1985
Mark S. Eberhardt, D. K. Wagener, T. J. Orchard, R. E. LaPorte, D. E. Cavender, B. S. Rabin, R. W. Atchison, L. H. Kuller, Allan Drash, D. J. Becker
Value of antibodies to islet protein tyrosine phosphatase-like molecule in predicting type 1 diabetes
Diabetes - Tập 46 Số 8 - Trang 1270-1275 - 1997
Mohammed I. Hawa, Rachel Rowe, Michael S. Lan, Abner Louis Notkins, P. Pozzilli, M. R. Christie, R. D. G. Leslie
Pancreatic islet cell cytoplasmic antibody in diabetes is represented by antibodies to islet cell antigen 512 and glutamic acid decarboxylase
Diabetes - Tập 44 Số 11 - Trang 1290-1295 - 1995
Mark A. Myers, D. U. Rabin, M. J. Rowley
Antibodies to islet 37k antigen, but not to glutamate decarboxylase, discriminate rapid progression to IDDM in endocrine autoimmunity
Diabetes - Tập 43 Số 10 - Trang 1254-1259 - 1994
M. R. Christie, Salvatore Genovese, David D. Cassidy, Emanuele Bosi, Thomas J. Brown, Meizan Lai, Ezio Bonifacio, G. F. Bottazzo
Prediction of IDDM in the general population: strategies based on combinations of autoantibody markers
Diabetes - Tập 46 Số 11 - Trang 1701-1710 - 1997
P. J. Bingley, Ezio Bonifacio, Alistair J.K. Williams, S. Genovese, G. F. Bottazzo, Elaine Gale
Diabetes Antibody Standardization Program: First Assay Proficiency Evaluation
Diabetes - Tập 52 Số 5 - Trang 1128-1136 - 2003
Polly J. Bingley, Ezio Bonifacio, Patricia W. Mueller
The aims of the first proficiency evaluation of the Diabetes Antibody Standardization Program (DASP) were to assess general implementation of assay methods and to evaluate the new World Health Organization (WHO) reference reagent for autoantibodies to GAD and IA-2. Forty-six laboratories in 13 countries received coded sera from 50 patients with newly diagnosed type 1 diabetes and 50 blood donor co... hiện toàn bộ
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