Hypoglycemia Abrogates the Vascular Endothelial Protective Effect of Exenatide in Type 2 Diabetes MellitusDiabetes Therapy - Tập 10 - Trang 1127-1132 - 2019
Keiichi Torimoto, Yosuke Okada, Yoshiya Tanaka
Glucagon-like peptide-1 (GLP-1) receptor agonists improve postprandial glucose, lipid metabolism, and vascular endothelial function. However, little is known about the effect of hypoglycemia on vascular endothelial function in patients on GLP-1 receptor agonist therapy. The aim of the present study was to determine the effect of hypoglycemia on vascular endothelial function in patients with type 2...... hiện toàn bộ
Real-World Evaluation of GLP-1 Receptor Agonist Therapy Persistence, Adherence and Therapeutic Inertia Among Obese Adults with Type 2 DiabetesDiabetes Therapy - Tập 14 - Trang 723-736 - 2023
Ana Palanca, F. Javier Ampudia-Blasco, José Miguel Calderón, Inmaculada Sauri, Sergio Martinez-Hervás, José Luis Trillo, Josep Redón, José T. Real
In type 2 diabetes (T2D), key barriers to optimal glycaemic control include lack of persistence with treatment, reduced medication adherence and therapeutic inertia. This study aimed to assess the impact of these barriers in obese adults with type 2 diabetes treated with a GLP-1 receptor agonist (GLP-1RA) and compare them against other glucose-lowering agents in a real-world setting. A retrospecti...... hiện toàn bộ
Management of Diabetic Foot UlcersDiabetes Therapy - Tập 3 - Trang 1-15 - 2012
Kleopatra Alexiadou, John Doupis
Diabetic foot is a serious complication of diabetes which aggravates the patient’s condition whilst also having significant socioeconomic impact. The aim of the present review is to summarize the causes and pathogenetic mechanisms leading to diabetic foot, and to focus on the management of this important health issue. Increasing physicians’ awareness and hence their ability to identify the “foot a...... hiện toàn bộ
InRange: Comparison of the Second-Generation Basal Insulin Analogues Glargine 300 U/mL and Degludec 100 U/mL in Persons with Type 1 Diabetes Using Continuous Glucose Monitoring—Study DesignDiabetes Therapy - Tập 11 - Trang 1017-1027 - 2020
Tadej Battelino, Zsolt Bosnyak, Thomas Danne, Bhaswati Mukherjee, Steve Edelman, Valerie Pilorget, Pratik Choudhary, Eric Renard, Richard Bergenstal
Suboptimal glycaemic control among people with type 1 diabetes (T1D) is known to lead to long-term micro- and macrovascular complications and, unfortunately, it is still prevalent even in the most affluent societies. Although glycated haemoglobin monitoring is considered to be the gold standard for assessing glycaemic control, such monitoring is unable to reliably measure acute glycaemic excursion...... hiện toàn bộ
Does Current Diabetes Technology Improve Metabolic Control? A Cross-Sectional Study on the Use of Insulin Pumps and Continuous Glucose Monitoring Devices in a Nationwide Pediatric PopulationDiabetes Therapy - Tập 12 - Trang 2571-2583 - 2021
Heiko Bratke, Hanna D. Margeirsdottir, Jörg Assmus, Pål R. Njølstad, Torild Skrivarhaug
To examine the use of multiple daily injections (MDI), insulin pumps, self-measured blood glucose (SMBG), and continuous glucose monitoring (CGM) systems, and their association with glycated hemoglobin (HbA1c), diabetic ketoacidosis (DKA), and severe hypoglycemia. In a pediatric population-based nationwide cross-sectional study, we analyzed data from 2623 participants up to 18 years of age with ty...... hiện toàn bộ
Insulinization in T2DM with Basal Analogues During COVID-19 Pandemic: Expert Opinion from an Indian PanelDiabetes Therapy - Tập 12 - Trang 133-142 - 2020
Manoj Chawla, Sunil M. Jain, Jothydev Kesavadev, Brij M. Makkar, Vijay Viswanathan, Mangesh Tiwaskar, Aravind R. Sosale, Vijay Negalur, Kirtikumar D. Modi, Mukulesh Gupta, Surinder Kumar, Santosh Ramakrishnan, Nilakshi Deka, Nirmalya Roy
The ongoing global pandemic of the coronavirus disease 2019 (COVID-19) has placed a severe strain on the management of chronic conditions like diabetes. Optimal glycemic control is always important, but more so in the existing environment of COVID-19. In this context, timely insulinization to achieve optimal glycemic control assumes major significance. However, given the challenges associated with...... hiện toàn bộ