Real-World Experience of Methotrexate in the Treatment of Skin Diseases: an Italian Delphi ConsensusDermatology and Therapy - Tập 13 - Trang 1219-1241 - 2023
Giovanni Damiani, Paolo Amerio, Federico Bardazzi, Carlo G. Carrera, Andrea Conti, Francesco Cusano, Paolo Dapavo, Clara DeSimone, May El Hachem, Gabriella Fabbrocini, Paolo Gisondi, Francesco Loconsole, Giuseppe Micali, Iria Neri, Aurora Parodi, Stefano Piaserico, Marco Romanelli, Luca Stingeni, Paolo D. M. Pigatto
After decades of use, methotrexate displays an established safety and efficacy
profile in both in-hospital and outpatient settings. Despite its widespread use,
there is surprisingly little clinical evidence to guide daily practice with
methotrexate in dermatology. To provide guidance for clinicians in daily
practice for areas in which there is limited guidance. A Delphi consensus
exercise on 23 st... hiện toàn bộ
Crisaborole Ointment Improves Quality of Life of Patients with Mild to Moderate Atopic Dermatitis and Their FamiliesDermatology and Therapy - Tập 8 - Trang 605-619 - 2018
Eric L. Simpson, Amy S. Paller, Mark Boguniewicz, Lawrence F. Eichenfield, Steven R. Feldman, Jonathan I. Silverberg, Sarah L. Chamlin, Lee T. Zane
The impact of crisaborole ointment, a nonsteroidal phosphodiesterase 4 inhibitor
for the treatment of mild to moderate atopic dermatitis (AD), on quality of life
(QoL) was assessed in two identically designed phase 3 studies (AD-301:
NCT02118766; AD-302: NCT02118792, both at http://www.clinicaltrials.gov ). In
both studies, patients aged ≥ 2 years with mild to moderate AD per the
Investigator’s St... hiện toàn bộ
Botulinum Toxin A Alleviates Persistent Erythema and Flushing in Patients with Erythema Telangiectasia RosaceaDermatology and Therapy - Tập 12 - Trang 2285-2294 - 2022
Rongli Yang, Chang Liu, Wenli Liu, Jintian Luo, Shaoli Cheng, Xin Mu
The persistent erythema and flushing seen in some cases of rosacea do not
respond effectively to, or may easily relapse after, oral medication or
light-based therapies (laser or intense pulsed light). Intradermal botulinum
toxin A (BTX-A) injection can be used to treat intractable erythema and
flushing, but studies with large samples and long-term observation have not been
conducted to determine i... hiện toàn bộ
Patients with Chronic Urticaria Remain Largely Undertreated: Results from the DERMLINE Online SurveyDermatology and Therapy - Tập 11 - Trang 1027-1039 - 2021
Nicola Wagner, Alexander Zink, Katharina Hell, Maximilian Reinhardt, Katrin Romer, Elena Hillmann, Daniel Baeumer, Maximilian C. Schielein
Chronic urticaria (CU) is an unpredictable disease, with high disease burden and
a significant negative impact on quality of life, especially in patients of
working age. Many patients are undertreated, and there is poor awareness of
strategies to manage patients with CU in the real-world setting. The current
study aimed to gain a better understanding of CU from the patients’ perspective,
including... hiện toàn bộ
A Real-World, Non-interventional Indian Study Evaluating Intensive Plant-Based Butter Moisturizing Cream in PsoriasisDermatology and Therapy - Tập 9 - Trang 537-546 - 2019
Hemangi Rajiv Jerajani, Jayakar Thomas, Alka Gupta, Gurram Narasimha Rao Netha, Ranju Chawla, Rashid Shaikh, Ravindra Babu, Irene Williams, Prajakta Talathi, Suyog C. Mehta, Rajan Mittal, Shivani Acharya, Sujeet N. Charugulla
Psoriasis is estimated to affect 0.44–2.8% of the Indian population.
Moisturizers are a key adjuvant psoriasis treatment strategy, but data regarding
their effectiveness, safety and compliance pattern in an Indian context are
lacking. Hence, this real-world study on an intensive plant-based butter
moisturizing cream (Venusia ® Max) was conducted among Indian patients with
psoriasis. This was an ob... hiện toàn bộ
Evaluation of Psychological Wellbeing and Social Impact of Combined Facial and Truncal Acne: a Multi-national, Mixed-Methods StudyDermatology and Therapy - Tập 12 - Trang 1847-1858 - 2022
Jerry Tan, Stefan Beissert, Fran Cook-Bolden, Rajeev Chavda, Julie Harper, Adelaide Hebert, Edward Lain, Alison Layton, Marco Rocha, Jonathan Weiss, Brigitte Dréno
Half of the individuals with facial acne develop truncal acne, but the impact of
combined facial and truncal acne (CA) on patients’ quality of life is poorly
researched. A 60-min interview of 30 participants with CA was conducted that
formed the basis for a cross-sectional survey of 694 adolescents and adults with
CA. The main themes identified from the qualitative interviews among CA subjects
inc... hiện toàn bộ
Impact and Management of Loss of Eyebrows and EyelashesDermatology and Therapy - Tập 13 - Trang 1243-1253 - 2023
Michela Starace, Stephano Cedirian, Aurora M. Alessandrini, Francesca Bruni, Federico Quadrelli, Daniel F. Melo, Tatiana Silyuk, Andrei Doroshkevich, Bianca M. Piraccini, Matilde Iorizzo
Eyelashes and eyebrows have different functions, ranging from practical purposes
such as protecting the eye apparatus from external hazards to the definition of
our facial expression. For this reason, their loss could have both functional
and psychological impact on patients’ quality of life. Complete or partial loss
can occur any time during life, and identifying the cause is mandatory to
establi... hiện toàn bộ