DNA Research

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Characterization of Mononucleotide Repeats in Sequenced Prokaryotic Genomes
DNA Research - Tập 12 Số 4 - Trang 221-233 - 2005
Tom Coenye, Peter Vandamme
The chromosome-level genome assembly of <i>Gentiana dahurica</i> (Gentianaceae) provides insights into gentiopicroside biosynthesis
DNA Research - Tập 29 Số 2 - 2022
Ting Li, Yu Xi, Yumeng Ren, Minghui Kang, Wenjie Yang, Landi Feng, Quanjun Hu
Abstract Gentiana dahurica Fisch. is a perennial herb of the family Gentianaceae. This species is used as a traditional Tibetan medicine because of its rich gentiopicroside constituents. Here, we generate a high-quality, chromosome-level genome of G. dahurica with a total length of 1,416.54 Mb. Comparative genomic analyses showed that G. dahurica shared one whole-genome duplication (WGD) event with Gelsemium sempervirens of the family Gelsemiaceaei and had one additional species-specific WGD after the ancient whole-genome triplication with other eudicots. Further transcriptome analyses identified numerous enzyme coding genes and the transcription factors related to gentiopicroside biosynthesis. A set of candidate cytochrome P450 genes were identified for being involved in biosynthetic shifts from swertiamarin to gentiopicroside. Both gene expressions and the contents measured by high-performance liquid chromatography indicated that the gentiopicrosides were mainly synthesized in the rhizomes with the highest contents. In addition, we found that two above-mentioned WGDs, contributed greatly to the identified candidate genes involving in gentiopicroside biosynthesis. The first reference genome of Gentianaceae we generated here will definitely accelerate evolutionary, ecological, and pharmaceutical studies of this family.
Sequence Analysis of the Genome of the Unicellular Cyanobacterium Synechocystis sp. Strain PCC6803. II. Sequence Determination of the Entire Genome and Assignment of Potential Protein-coding Regions
DNA Research - Tập 3 Số 3 - Trang 109-136 - 1996
Takakazu Kaneko, Shusei Sato, Hirokazu Kotani, Ayako Tanaka, E. Asamizu, Yasukazu Nakamura, Nobuyuki Miyajima, Makoto Hirosawa, Masahiro Sugiura, Shigemi Sasamoto, Takaharu Kimura, Tsutomu Hosouchi, Ai Matsuno, A. Muraki, N. Nakazaki, K. Naruo, S. Okumura, Sayaka Shimpo, Chie Takeuchi, T. Wada, Akiko Watanabe, Manabu Yamada, Miho Yasuda, Sho Tabata
Escherichia coli Histone-Like Protein H-NS Preferentially Binds to Horizontally Acquired DNA in Association with RNA Polymerase
DNA Research - Tập 13 Số 4 - Trang 141-153 - 2006
Taku Oshima, Shu Ishikawa, Ken Kurokawa, Hirofumi Aiba, Naotaka Ogasawara
Complete Chloroplast Genome Sequence of a Major Allogamous Forage Species, Perennial Ryegrass (Lolium perenne L.)
DNA Research - Tập 16 Số 3 - Trang 165-176 - 2009
Kerstin Diekmann, Trevor R. Hodkinson, Kenneth H. Wolfe, Rob Jozef Matheus van den Bekerom, Philip J. Dix, Susanne Barth
Prediction of the Coding Sequences of Unidentified Human Genes. XIV. The Complete Sequences of 100 New cDNA Clones from Brain Which Code for Large Proteins in vitro
DNA Research - Tập 6 Số 3 - Trang 197-205 - 1999
Makiko Suwa, Takahiro Nagase, Ken–Ichi Ishikawa, Makoto Hirosawa, Nobuyuki Miyajima, Ayako Tanaka, Hirokazu Kotani, Nobuhiko Nomura, Yoshinori Hasegawa
Prediction of the Coding Sequences of Unidentified Human Genes. XII. The Complete Sequences of 100 New cDNA Clones from Brain Which Code for Large Proteins in vitro
DNA Research - Tập 5 Số 6 - Trang 355-364 - 1998
Takahiro Nagase, Ken Ishikawa, Mikita Suyama, Makiko Suwa, Makoto Hirosawa, Nobuyuki Miyajima, Ayako Tanaka, Hirokazu Kotani, Nobuhiko Nomura, Osamu Ohara
Complete Genome Sequence of Enterohemorrhagic Eschelichia coli O157:H7 and Genomic Comparison with a Laboratory Strain K-12
DNA Research - Tập 8 Số 1 - Trang 11-22 - 2001
Tetsuya Hayashi
Sex-specific markers developed by next-generation sequencing confirmed an XX/XY sex determination system in bighead carp (Hypophthalmichthys nobilis) and silver carp (Hypophthalmichthys molitrix)
DNA Research - Tập 25 Số 3 - Trang 257-264 - 2018
Haiyang Liu, Meixia Pang, Xiaomu Yu, Ying Zhou, Jingou Tong, Beide Fu
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