Current Tropical Medicine Reports
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Chikungunya and Its Interaction With the Host Cell
Current Tropical Medicine Reports - Tập 2 - Trang 22-29 - 2015
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus belonging to the Togaviridae family. It is a virus with a single-stranded, positive sense RNA genome, maintained in a sylvatic and urban cycle, involving humans and mosquitoes from Aedes species, mainly Aedes aegypti and Aedes albopictus. In less than 10 years, CHIKV has spread from the coast of Kenya throughout the Indian Ocean, Pacif......
Possibility of Leishmania Transmission via Lutzomyia spp. Sand Flies Within the USA and Implications for Human and Canine Autochthonous Infection
Current Tropical Medicine Reports - Tập 9 Số 4 - Trang 160-168
Epidemiology of Chagas Disease in the USA: High-Risk Patient Populations for Screening
Current Tropical Medicine Reports - Tập 6 - Trang 8-12 - 2019
The goals of this paper are to review the current data on the prevalence of Chagas disease in the USA and to describe the obstacles to expanding screening efforts. Latin American immigrants appear to be at a significantly higher risk of contracting Chagas disease than are individuals born in the USA, though the risk of autochthonous transmission is likely underestimated. Rates of Chagas disease in......
The Placenta and Plasmodium Infections: a Case Study from Blue Nile State, Sudan
Current Tropical Medicine Reports - Tập 7 - Trang 153-160 - 2020
Sequestration of Plasmodium-infected cells in the placenta causes significant adverse effects on mothers and their fetuses. With progress in understanding placental malaria and associated adverse consequences, this review addresses the situation in an area with high prevalence, in Blue Nile State, Sudan, where protective interventions are not adequately provided. Several studies have confirmed tha......
Sphingolipids, Lipid Rafts, and Giardial Encystation: The Show Must Go On
Current Tropical Medicine Reports - Tập 2 - Trang 136-143 - 2015
Sphingolipids are sphingosine-based phospholipids, which are present in the plasma and endomembranes of many eukaryotic cells. These lipids are involved in various cellular functions, including cell growth, differentiation, and apoptosis. In addition, sphingolipid and cholesterol-enriched membrane microdomains (also called “lipid rafts”) contain a set of proteins and lipids, which take part in the......
Schistosomiasis in EuropeAbstract
Purposeof Review
The purpose of this review is to provide an overview of the burden of schistosomiasis in the European continent. It discusses three subjects: the endemic forms of non-human schistosomiasis in Europe; the introduction of transmission of human schistosomiasis into Europe; and... ...
Current Tropical Medicine Reports -
Immunization Strategies for the Control of Histoplasmosis
Current Tropical Medicine Reports - Tập 6 - Trang 35-41 - 2019
Histoplasmosis is an infection caused by the dimorphic fungus Histoplasma capsulatum. Histoplasmosis is typically self-limited and presents asymptomatically in most people. Nevertheless, histoplasmosis can cause severe pulmonary disease and death. Histoplasmosis is increasingly found worldwide; however, it is best documented in the endemic region of the Mississippi river valley system in the Easte......
Coxiella burnetii Infection in Livestock, Pets, Wildlife, and Ticks in Latin America and the Caribbean: a Comprehensive Review of the Literature
Current Tropical Medicine Reports - Tập 10 - Trang 94-137 - 2023
Q fever
, a bacterial zoonosis caused by Coxiella burnetii, is reported very heterogeneously in humans in Latin America. The objective of this study was to review the data on Coxiella burnetii Infection in animals in Latin America and the Caribbean. A comprehensive literature review was carried out in the 47 countries and territories of Latin America on various search engines and grouped into four......
Exploiting Lipids to Develop Anticryptococcal Vaccines
Current Tropical Medicine Reports - Tập 6 - Trang 55-63 - 2019
Cryptococcus spp. are responsible for life-threatening infections in humans causing mortality rates of 70% in developing countries. Antifungal therapy to combat cryptococcosis is based on the combination of amphotericin B, azoles, and 5-flucytosine. However, treatment failure is frequently triggered by antifungal resistance, drug-drug interactions, and toxicity. New alternatives to prevent cryptoc......
Animal Models for Melioidosis
Current Tropical Medicine Reports - Tập 4 - Trang 208-222 - 2017
Development, testing, and evaluation of medical countermeasures for melioidosis are hampered by a lack of well-characterized and standardized animal models. Recent work has both refined existing animal models for this disease and identified new ones. Head-to-head comparisons of mouse strains with varying susceptibility to the organism and using different routes of infection highlighted and confirm......
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