Current Treatment Options in Rheumatology
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Anti-malarials: Are There Benefits Beyond Mild Disease?
Current Treatment Options in Rheumatology - - 2016
Management of Cancer-Associated Myositis
Current Treatment Options in Rheumatology - Tập 8 - Trang 91-104 - 2022
Cancer-associated myositis (CAM) is defined as when cancer appears within 3 years of myositis onset. Dermatomyositis and seronegative immune–mediated necrotizing myopathy are the phenotypes mostly related to cancer. In general, treatment principles in myositis patients with and without CAM are similar. However, some aspects of myositis management are particular to CAM, including (a) the need for a...... hiện toàn bộ
Measuring Disease Progression in Osteoarthritis
Current Treatment Options in Rheumatology - Tập 2 - Trang 97-110 - 2016
Radiographs are a commonly used tool to assess disease progression in osteoarthritis (OA). However, it is not the preferred method of defining and following OA progression. While it is moderately responsive to change in terms of standardised response means (SRM), it is insensitive to change in cartilage measures. MRI offers a much better assessment, and OA features are much better targeted for def...... hiện toàn bộ
Use of Rituximab in the Management of Sjögren’s Syndrome
Current Treatment Options in Rheumatology - Tập 1 - Trang 277-291 - 2015
Primary Sjögren’s syndrome (pSS) is an autoimmune disease, showing a broad heterogeneity concerning the symptoms, the involved organs, as well as the prognosis. The clinical presentation, in the majority of patients, is limited to the mucosal surfaces, although some patients may show a systemic involvement and/or immunological bio-markers strongly associated with a higher risk to develop lymphoma....... hiện toàn bộ
Past, Present, and Future in Dermatomyositis Therapeutics
Current Treatment Options in Rheumatology - Tập 8 Số 4 - Trang 71-90
Exercise in Myositis
Current Treatment Options in Rheumatology - Tập 4 - Trang 289-298 - 2018
A growing body of evidence supports exercise as a very important part of the treatment for adult patients with idiopathic inflammatory myopathies (IIM). This review mainly focuses on exercise studies published during the last 2 years in adult myositis. During the last couple of years, new publications present further evidence for intensive endurance exercise as an anti-inflammatory treatment induc...... hiện toàn bộ
Management of Antiphospholipid Syndrome in Patients with Systemic Lupus Erythematosus
Current Treatment Options in Rheumatology - Tập 5 - Trang 190-200 - 2019
To provide an approach to primary and secondary prevention of thrombotic events and obstetric complications in patients with antiphospholipid antibodies (aPL) with or without antiphospholipid syndrome (APS), particularly in association with systemic lupus erythematosus (SLE). The available evidence would suggest that direct oral anticoagulants are inferior to warfarin at prevention of recurrent th...... hiện toàn bộ
Bisphosphonate Drug Holiday and Fracture Risk: Reviewing the Evidence
Current Treatment Options in Rheumatology - Tập 8 - Trang 37-55 - 2022
This paper reviews evidence in support of or counter to the use of bisphosphonate (BP) drug holiday to minimize the occurrence of rare adverse events such as atypical femoral fracture, while maintaining the osteoporosis-related fracture prevention benefit conferred by the medication. Fracture prevention benefit achieved with 3–5 years of BP treatment appears to be maintained during holiday for wom...... hiện toàn bộ
Contraception in Systemic Lupus Erythematosus (SLE)
Current Treatment Options in Rheumatology - Tập 5 - Trang 346-362 - 2019
To identify an approach for contraception use in systemic lupus erythematosus (SLE), we take an in-depth look at the available contraceptive methods for female patients, their safety profile and possible drug interactions. Among the possible options, long-acting reversible contraceptives (LARCs) are considered the most effective option and should be considered in most cases. Combined hormonal cont...... hiện toàn bộ
Challenges and Advances in SLE Autoantibody Detection and Interpretation
Current Treatment Options in Rheumatology - Tập 5 - Trang 147-167 - 2019
This review is an overview of key autoantibodies used in the diagnosis and management of SLE. Questions addressed are the advantages to but limitations of ANA testing and what are the key considerations in ordering ANA tests and then interpreting the ANA results. There is a progressive move towards • Solid-phase multi-analyte arrays with algorithmic analysis (SPMAAA) • Closing the seronegative gap...... hiện toàn bộ
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