The Status of Evidence-Based Treatments for Moral Injury Syndrome: Review and Meta-analysis of Randomized Controlled TrialsCurrent Treatment Options in Psychiatry - Tập 10 - Trang 217-233 - 2023
Stephen L. Aita, Susannah R. Kondrath, Tyler Owen, Nicholas C. Borgogna, Timothy J. Usset
The goals of this report were to (a) review the empirical evidence of
interventions for moral injury syndrome (MIS) symptoms, (b) quantitatively
synthesize these effects through a preliminary meta-analysis, and (c) provide
treatment and research recommendations for MIS based on our qualitative and
quantitative review. Participants in MIS treatment improved on targeted MIS
symptoms and general ment... hiện toàn bộ
Neurofeedback in the Treatment of Early Life Stress: a “Nudge” for the Nervous System?Current Treatment Options in Psychiatry - Tập 8 - Trang 77-94 - 2021
Mark Gapen, Travers Guy
Early life stress has been shown to have profound effects on the developmental
trajectories of individuals. Findings have implicated most major areas of the
brain as being affected, and existing treatments have been limited in
ameliorating symptoms. The purpose of this review is to focus on the development
of the autonomic nervous system in concert with the brain. We suggest that the
majority of p... hiện toàn bộ
Bipolar Disorder in Primary Care: Considerations in ManagementCurrent Treatment Options in Psychiatry - Tập 5 - Trang 441-451 - 2018
Hilja Ruegg, Suzanne Watson, Melissa DelBello, Caleb Adler, L. Rodrigo Patino Duran
Bipolar disorder is a chronic mental illness that has significant morbidity and
mortality implications globally. Increasingly, as with many mental health
disorders, patients are being identified in primary care settings. In this
overview, we discuss screening and case identification, making the case for
judicious use of screening tools coupled with follow-up clarifying questions. We
review the mai... hiện toàn bộ
Psychostimulant Augmentation of Antidepressant Therapy in Depression: a Systematic Review and Meta-AnalysisCurrent Treatment Options in Psychiatry - Tập 10 - Trang 492-510 - 2023
Duarte Janela, Joana Jerónimo, João Rema, Diogo Telles-Correia, Filipa Novais
To evaluate the effectiveness of psychostimulant augmentation of antidepressants
in the treatment of depression in adults. In our analysis of 13 RCTs involving
2478 participants, psychostimulant augmentation demonstrated a statistically
significant reduction in depressive symptom severity compared to placebo
augmentation (N = 1827; SMD = − 0.18; 95% CI (− 0.36, − 0.01); p = 0.04,
I2 = 65%). Howev... hiện toàn bộ
Double-Blind Randomized Placebo-Controlled Trials in the Treatment of Affective Disorders: Problems and AlternativesCurrent Treatment Options in Psychiatry - Tập 2 - Trang 262-270 - 2015
E. Severus, E. Laber, I. Lipkovich
Double-blind randomized placebo-controlled trials, in which a new
approval-seeking drug is compared to placebo, are generally considered to be the
gold standard for evaluating the efficacy of a psychopharmacological
intervention in the treatment of affective disorders. However, this type of
study has substantial limitations regarding the external validity of its
results. Therefore, alternatives wi... hiện toàn bộ
The Treatment of Pediatric Suicidal BehaviorCurrent Treatment Options in Psychiatry - Tập 1 - Trang 66-83 - 2014
Taylor Burke, Jacqueline Buchanan, Leora Amira, Kseniya Yershova, Kelly Posner
Psychotherapies have stronger empirical support of efficacy and do not have
safety concerns associated with many medications; thus, at present,
psychotherapy is an appropriate first-line treatment for suicidal ideation and
behavior in youth. Integrated Cognitive-Behavioral Therapy (I-CBT) and
Multisystemic Therapy (MST) have the strongest preliminary evidence for
psychotherapeutic treatment of sui... hiện toàn bộ
Self-Ratings of Personality Pathology: Insights Regarding Their Validity and Treatment UtilityCurrent Treatment Options in Psychiatry - Tập 6 - Trang 299-311 - 2019
Kasey Stanton, Matthew F. D. Brown, Meredith A. Bucher, Caroline Balling, Douglas B. Samuel
The validity of self-ratings of personality pathology often is questioned
because personality disorders (PD) historically have been viewed as being
characterized by poor insight. However, recent research indicates that PD
self-ratings are valid in many ways and have significant clinical utility.
Building upon this growing literature, our goal here is to provide practical
discussion of how incorpor... hiện toàn bộ
The Role of Social Determinants of Health in Moral Injury: Implications and Future DirectionsCurrent Treatment Options in Psychiatry - Tập 9 - Trang 202-214 - 2022
Lauren M. Borges, Alisha Desai, Sean M. Barnes, Jacob P. S. Johnson
Exposure to potentially morally injurious events (PMIEs) and the development of
moral injury have yet to be conceptualized as they relate to social determinants
of health (SDoH). Recent Findings. In this paper, the extant literature on moral
injury and SDoH is reviewed. Specific individual-level SDoH, including gender,
sex, sexual orientation, race, and ethnicity, are explored relative to PMIEs an... hiện toàn bộ