The Status of Evidence-Based Treatments for Moral Injury Syndrome: Review and Meta-analysis of Randomized Controlled TrialsCurrent Treatment Options in Psychiatry - Tập 10 - Trang 217-233 - 2023
Stephen L. Aita, Susannah R. Kondrath, Tyler Owen, Nicholas C. Borgogna, Timothy J. Usset
The goals of this report were to (a) review the empirical evidence of interventions for moral injury syndrome (MIS) symptoms, (b) quantitatively synthesize these effects through a preliminary meta-analysis, and (c) provide treatment and research recommendations for MIS based on our qualitative and quantitative review. Participants in MIS treatment improved on targeted MIS symptoms and general ment...... hiện toàn bộ
Neurofeedback in the Treatment of Early Life Stress: a “Nudge” for the Nervous System?Current Treatment Options in Psychiatry - Tập 8 - Trang 77-94 - 2021
Mark Gapen, Travers Guy
Early life stress has been shown to have profound effects on the developmental trajectories of individuals. Findings have implicated most major areas of the brain as being affected, and existing treatments have been limited in ameliorating symptoms. The purpose of this review is to focus on the development of the autonomic nervous system in concert with the brain. We suggest that the majority of p...... hiện toàn bộ
Bipolar Disorder in Primary Care: Considerations in ManagementCurrent Treatment Options in Psychiatry - Tập 5 - Trang 441-451 - 2018
Hilja Ruegg, Suzanne Watson, Melissa DelBello, Caleb Adler, L. Rodrigo Patino Duran
Bipolar disorder is a chronic mental illness that has significant morbidity and mortality implications globally. Increasingly, as with many mental health disorders, patients are being identified in primary care settings. In this overview, we discuss screening and case identification, making the case for judicious use of screening tools coupled with follow-up clarifying questions. We review the mai...... hiện toàn bộ
Psychostimulant Augmentation of Antidepressant Therapy in Depression: a Systematic Review and Meta-AnalysisCurrent Treatment Options in Psychiatry - Tập 10 - Trang 492-510 - 2023
Duarte Janela, Joana Jerónimo, João Rema, Diogo Telles-Correia, Filipa Novais
To evaluate the effectiveness of psychostimulant augmentation of antidepressants in the treatment of depression in adults. In our analysis of 13 RCTs involving 2478 participants, psychostimulant augmentation demonstrated a statistically significant reduction in depressive symptom severity compared to placebo augmentation (N = 1827; SMD = − 0.18; 95% CI (− 0.36, − 0.01); p = 0.04, I2 = 65%). Howev...... hiện toàn bộ
Double-Blind Randomized Placebo-Controlled Trials in the Treatment of Affective Disorders: Problems and AlternativesCurrent Treatment Options in Psychiatry - Tập 2 - Trang 262-270 - 2015
E. Severus, E. Laber, I. Lipkovich
Double-blind randomized placebo-controlled trials, in which a new approval-seeking drug is compared to placebo, are generally considered to be the gold standard for evaluating the efficacy of a psychopharmacological intervention in the treatment of affective disorders. However, this type of study has substantial limitations regarding the external validity of its results. Therefore, alternatives wi...... hiện toàn bộ
The Treatment of Pediatric Suicidal BehaviorCurrent Treatment Options in Psychiatry - Tập 1 - Trang 66-83 - 2014
Taylor Burke, Jacqueline Buchanan, Leora Amira, Kseniya Yershova, Kelly Posner
Psychotherapies have stronger empirical support of efficacy and do not have safety concerns associated with many medications; thus, at present, psychotherapy is an appropriate first-line treatment for suicidal ideation and behavior in youth. Integrated Cognitive-Behavioral Therapy (I-CBT) and Multisystemic Therapy (MST) have the strongest preliminary evidence for psychotherapeutic treatment of sui...... hiện toàn bộ
Self-Ratings of Personality Pathology: Insights Regarding Their Validity and Treatment UtilityCurrent Treatment Options in Psychiatry - Tập 6 - Trang 299-311 - 2019
Kasey Stanton, Matthew F. D. Brown, Meredith A. Bucher, Caroline Balling, Douglas B. Samuel
The validity of self-ratings of personality pathology often is questioned because personality disorders (PD) historically have been viewed as being characterized by poor insight. However, recent research indicates that PD self-ratings are valid in many ways and have significant clinical utility. Building upon this growing literature, our goal here is to provide practical discussion of how incorpor...... hiện toàn bộ
The Role of Social Determinants of Health in Moral Injury: Implications and Future DirectionsCurrent Treatment Options in Psychiatry - Tập 9 - Trang 202-214 - 2022
Lauren M. Borges, Alisha Desai, Sean M. Barnes, Jacob P. S. Johnson
Exposure to potentially morally injurious events (PMIEs) and the development of moral injury have yet to be conceptualized as they relate to social determinants of health (SDoH). Recent Findings. In this paper, the extant literature on moral injury and SDoH is reviewed. Specific individual-level SDoH, including gender, sex, sexual orientation, race, and ethnicity, are explored relative to PMIEs an...... hiện toàn bộ