Current Treatment Options in Infectious Diseases
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Update on Adverse Effects of HIV Integrase Inhibitors
Current Treatment Options in Infectious Diseases - Tập 11 - Trang 372-387 - 2019
The goal of this paper is to provide an up-to-date review of adverse events
related to the class of integrase strand transfer inhibitors (INSTIs), which
became the class of choice in few years. We sought answers specifically to
issues pertaining to neuropsychiatric adverse events, as well as weight gain,
which were the two most important categories of adverse events raised in recent
studies based ...
What Is New in Candida Infections? T2Candida, Antifungal Stewardship, and Candida auris
Current Treatment Options in Infectious Diseases - Tập 12 - Trang 1-12 - 2020
We review T2Candida panel performance in diagnosing invasive candidiasis,
potential roles of T2Candida, and other culture-independent tests in patient
management and antifungal stewardship, and diagnosis and treatment of infections
by Candida auris, which has emerged globally as a cause of nosocomial outbreaks.
In 2 multicenter trials, T2Candida was 90% sensitive and 98% specific for
diagnosing ca...
Improving Diagnostic and Laboratory Capacity Helps in Control of Infection: an Indian Perspective
Current Treatment Options in Infectious Diseases - Tập 12 - Trang 112-121 - 2020
To appraise the evidence and recommendations from published medical literature
about the importance of clinical microbiology laboratory services in the
prevention and control of infection in community and in the healthcare setting
especially from the Indian perspective. Effective infection prevention and
control (IPC) is not possible without a functioning microbiology laboratory.
Basic microbiolog...
Care Outcomes in People Living with HIV and Cancer
Current Treatment Options in Infectious Diseases - Tập 13 - Trang 83-99 - 2021
The evolving epidemiology of people living with HIV (PLWH) shows growing trends
towards age-related conditions and diseases. As antiretroviral therapies (ART)
have improved, AIDS-related cancers have declined but non-AIDS-related cancers
are on the rise. Despite advances in HIV care, there continues to be significant
health outcome disparities between PLWH with cancer compared to the general
popul...
Moving to a Dengue Preventive Treatment Through New Vaccines
Current Treatment Options in Infectious Diseases - Tập 9 - Trang 347-355 - 2017
Dengue fever is a viral disease with no curative treatment. However, symptomatic
treatment exists to alleviate the fever and provide analgesia to the multiple
types of pain mainly headache, arthralgia, myalgia, and retro-ocular pain.
Antiviral drugs to interfere with the process of viral replication are still
under investigation. In the past, homeopathic treatment has been tried as well,
with no s...
Antimicrobial Stewardship in Low- and Middle-Income Countries
Current Treatment Options in Infectious Diseases - Tập 10 - Trang 17-27 - 2018
Antimicrobial stewardship (AMS) is one of the core elements of infection
prevention and control, but in many resource-limited countries its
implementation is absent or suboptimal. There is inadequate information on the
best model for an AMS program. AMS should be adapted to each region according to
sociocultural dimensions, financing, and antimicrobial resistance. Many of
antimicrobials prescribed...
Malaria Therapeutic Paradigm: An Evolution Towards Commercial Drug Delivery Technology
Current Treatment Options in Infectious Diseases - - 2024
Malaria and other parasitic infections pose serious health risks to millions of
people worldwide each year. Oral medication is a crucial component in a
multi-prolonged approach to effectively managing malaria. The use of oral
antimalarial medications is essential for both treating and preventing malaria.
They are essential because of their effectiveness in focusing on the different
phases involved...
Treatment of Tropical and Travel Related Rickettsioses
Current Treatment Options in Infectious Diseases - Tập 8 - Trang 42-56 - 2016
Infections with organisms of the genera Rickettsia and Orientia are
undifferentiated in regard to their manifesting signs and symptoms. Hence, a
high degree of suspicion is required when a patient has a compatible illness
coupled with exposure to potential vectors. Confirmatory diagnosis is usually
retrospective, as it is obtained through serologic methods to determine
seroconversion or a fourfold...
Henipavirus Infection: Natural History and the Virus-Host Interplay
Current Treatment Options in Infectious Diseases - Tập 10 - Trang 197-216 - 2018
The review summarizes the history of the emergence of the Henipviruses, provides
a general introduction of their molecular biology and the efforts to develop
antiviral treatment strategies, including the successful development of a
veterinary vaccine. Paramyxoviridae, genus Henipavirus comprises emerging
pathogens detected in Southeast Asia, Australia and Africa. Henipaviruses are
enveloped with n...
Clostridium difficile Infection: Current and Emerging Therapeutics
Current Treatment Options in Infectious Diseases - Tập 7 - Trang 317-334 - 2015
Clostridium difficile infection (CDI) has been identified as a significant
threat to human health in the twenty-first century. Patients with CDI experience
diarrhea, gastrointestinal pain, and colonic inflammation that can be
life-threatening. Antibiotic therapy is successful at treating the majority of
patients with CDI, but an increased number of CDI cases over the last 15 years,
including sever...
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