Current Treatment Options in Infectious Diseases
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Discovering Drugs for the Treatment of Ebola Virus
Current Treatment Options in Infectious Diseases - Tập 9 - Trang 299-317 - 2017
Ebola virus, a member of the Filoviridae family, is a causative agent of severe viral hemorrhagic fever in humans. Over the past 40 years, the virus has been linked to several high mortality outbreaks in Africa with the recent West African outbreak resulting in over 11,000 deaths. This review provides a summary of the status of the drug discovery and development process for therapeutics for Ebola ...... hiện toàn bộ
Current Opinions in the Treatment of Pulmonary Nontuberculous Mycobacteria in Non-Cystic Fibrosis Patients: Mycobacterium abscessus Group, Mycobacterium avium Complex, and Mycobacterium kansasii
Current Treatment Options in Infectious Diseases - - 2014
A Practical Approach to Filtering Facepiece Respirator Decontamination and Reuse: Ultraviolet Germicidal Irradiation
Current Treatment Options in Infectious Diseases - Tập 13 - Trang 35-46 - 2021
Prior outbreaks of respiratory viruses have demonstrated the need for adequate personal protective equipment (PPE) for healthcare workers, particularly filtering facepiece respirators (FFR). Due to shortfalls of PPE during the SARS CoV-2 pandemic, the need for FFR decontamination and reuse (FFR-DR) strategies is paramount. This paper aims to discuss primary decontamination strategies, with an in-d...... hiện toàn bộ
Molecular Diagnosis in Fungal Infection Control
Current Treatment Options in Infectious Diseases - Tập 7 - Trang 1-13 - 2015
Fungal infections have been increasingly concerned because of their substantial morbidity and mortality especially among immunocompromised individuals. Early diagnosis is crucial and shown to improve treatment outcomes. The current goal standard methods including fungal culture and pathology are far from ideal due to their poor sensitivity, time consuming and invasive procedures often required. Mo...... hiện toàn bộ
Physician barriers to implementation of hospital-based antimicrobial stewardship programs (ASPs): a global perspective
Current Treatment Options in Infectious Diseases - Tập 11 - Trang 73-80 - 2019
Antimicrobial resistance (AMR) is a significant global health issue. Hospital-based antimicrobial stewardship programs (ASPs) are an important component of a “One Health” approach for addressing AMR. However, the adaptation and implementation of ASPs in low-resource settings often faces multiple barriers, which need to be identified and addressed to ensure program effectiveness. Barriers to ASPs a...... hiện toàn bộ
Outcome Assessments in Clinical Trials of Cryptococcal Meningitis: Considerations on Use of Early Fungicidal Activity as a Potential Surrogate Endpoint for All-Cause Mortality
Current Treatment Options in Infectious Diseases - Tập 6 - Trang 326-336 - 2014
Cryptococcal meningitis (CM) is a common disease in resource-challenged settings, with a high mortality within weeks of disease onset. Mortality remains high with current treatments, so more effective interventions are needed to decrease mortality. There has been interest in using the outcome assessment of quantification of fungus from cerebrospinal fluid as a replacement (surrogate) endpoint for ...... hiện toàn bộ
Henipavirus Infection: Natural History and the Virus-Host Interplay
Current Treatment Options in Infectious Diseases - Tập 10 - Trang 197-216 - 2018
The review summarizes the history of the emergence of the Henipviruses, provides a general introduction of their molecular biology and the efforts to develop antiviral treatment strategies, including the successful development of a veterinary vaccine. Paramyxoviridae, genus Henipavirus comprises emerging pathogens detected in Southeast Asia, Australia and Africa. Henipaviruses are enveloped with n...... hiện toàn bộ
Challenges in the Hospital Water System and Innovations to Prevent Healthcare-Associated Infections
Current Treatment Options in Infectious Diseases -
Can We Achieve Zero Hospital-Acquired Pneumonia?
Current Treatment Options in Infectious Diseases - Tập 10 Số 2 - Trang 153-168 - 2018
Managing the HIV/HCV-Co-Infected Patient in the Direct-Acting Antiviral Era: a Review of Pertinent Drug Interactions
Current Treatment Options in Infectious Diseases - - 2017
Purpose of Review With the advent of direct acting antiviral (DAAs) drugs, hepatitis c is now a curabledisease. The human immunodeficiency virus (HIV) and hepatitis c virus (HCV) have similar risk factorsfor acquisition, and thus the co-infected patient population provides its own set of unique challenges. Theclinical course, monitoring and treatment of co-infected patient...... hiện toàn bộ
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