Current Transplantation Reports

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Outcomes of Entecavir Prophylaxis in Hepatitis B Immune Patients Receiving Hepatitis B Infected Kidneys: A Single Center Experience
Current Transplantation Reports -
Sameera Muqueet, Nikhil A. Reddy, Anna Curtis, Machaiah Madhrira, Sridhar R. Allam, Ashraf I. Reyad
Postoperative Monitoring: Biomarkers and Alloimmune Responses and Their Relevance to Vascularized Composite Allotransplantation
Current Transplantation Reports - Tập 1 - Trang 203-210 - 2014
Gavin Whitehouse, Alberto Sanchez-Fueyo
Vascularized composite allotransplantation (VCA) is an evolving area of transplantation. Postoperative monitoring and immunosuppression strategies draw experience from solid organ transplantation, but VCA provides unique challenges as grafts incorporate histologically heterogenous tissues with differing degrees of antigenicity. In addition, such procedures are often life-improving rather than life... hiện toàn bộ
Vascularized Composite Allografts: Procurement, Allocation, and Implementation
Current Transplantation Reports - Tập 1 - Trang 173-182 - 2014
Axel Rahmel
Vascularized composite allotransplantation is a continuously evolving area of modern transplant medicine. Recently, vascularized composite allografts (VCAs) have been formally classified as ‘organs’. In this review, key aspects of VCA procurement are discussed, with a special focus on interaction with the procurement of classical solid organs. In addition, options for a matching and allocation sys... hiện toàn bộ
Cognitive Function in Kidney Transplantation
Current Transplantation Reports - Tập 7 - Trang 145-153 - 2020
Andrew Jurgensen, Abd Assalam Qannus, Aditi Gupta
Cognitive impairment is common in kidney transplant recipients and affects quality of life, graft survival, morbidity, and mortality. In this review article we discuss the epidemiology, diagnosis, pathophysiology, and future directions for cognitive impairment in kidney transplantation. We describe the potential role of pre-transplant cognition, immunosuppression, and peri-transplant factors in po... hiện toàn bộ
What Is Direct Allorecognition?
Current Transplantation Reports - Tập 3 - Trang 275-283 - 2016
Dominic A. Boardman, Jacinta Jacob, Lesley A. Smyth, Giovanna Lombardi, Robert I. Lechler
Direct allorecognition is the process by which donor-derived major histocompatibility complex (MHC)-peptide complexes, typically presented by donor-derived ‘passenger’ dendritic cells, are recognised directly by recipient T cells. In this review, we discuss the two principle theories which have been proposed to explain why individuals possess a high-precursor frequency of T cells with direct allos... hiện toàn bộ
Review of Major Drug-Drug Interactions in Thoracic Transplantation
Current Transplantation Reports - Tập 5 - Trang 220-230 - 2018
Yu Xie, Deanna Dilibero, David H. Chang
The first human lung transplant surgery in the world was done in 1963, followed by the first heart transplant in 1967, making this year its 50th anniversary. Since then, there has been great advancement in immunotherapy, with the adoption of calcineurin inhibitors (CNI), mycophenolate mofetil, and proliferation signal inhibitors (PSI). However, while these medications are crucial to maintenance of... hiện toàn bộ
Managing the Costs of Routine Follow-up Care After Living Kidney Donation: a Review and Survey of Contemporary Experience, Practices, and Challenges
Current Transplantation Reports -
Krista L. Lentine, Nagaraju Sarabu, Gwen McNatt, Robert Howey, Rebecca Hays, Christie P. Thomas, Ursula Lebron-Banks, Linda Ohler, Cody Wooley, Addie Wisniewski, Huiling Xiao, Andrea L. Tietjen
Abstract Purpose of Review While living organ donor follow-up is mandated for 2 years in the USA, formal guidance on recovering associated costs of follow-up care is lacking. In this review, we discuss current billing practices of transplant programs for living kidney donor follow-up, and propose future directions for managing follow-up costs and supporting cost neutrality in donor care. Recent Fi... hiện toàn bộ
The Intersection of Aging and Lung Transplantation: its Impact on Transplant Evaluation, Outcomes, and Clinical Care
Current Transplantation Reports -
Brittany Koons, Michaela R. Anderson, Patrick J. Smith, John R. Greenland, Jonathan P. Singer
Informed Consent of Living Kidney Donors: Pitfalls and Best Practice
Current Transplantation Reports - Tập 2 - Trang 29-34 - 2015
Rebecca E. Hays
Informed consent is clearly considered the ethical bedrock fundamental to living organ donation, a procedure lacking medical benefits for its participants. Recent guidelines have focused on strengthening content components of living kidney donor informed consent, including Organ Procurement and Transplantation Network (OPTN)/United Network for Organ Sharing (UNOS) policies that prescribe key compo... hiện toàn bộ
Preclinical Models in Vascularized Composite Allotransplantation
Current Transplantation Reports - Tập 2 - Trang 284-289 - 2015
C. Anton Fries, Dmitry W. Tuder, Michael R. Davis
Vascularized composite allotransplantation (VCA) has the potential to reconstruct any non-visceral tissue defect, using like for like tissue, delivering optimal form and function. Over 150 VCA transplants have been performed worldwide; however, this treatment remains experimental. Things systematically tried in the clinic should follow thorough science and tested in a model that allows predicting ... hiện toàn bộ
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