Structure-based Druggability Assessment of Anti-virulence Targets from Pseudomonas aeruginosaCurrent Protein and Peptide Science - Tập 20 Số 12 - Trang 1189-1203 - 2019
Thamires Quadros Froes, Regina L. Baldini, Sándor Vajda, Marcelo Santos Castilho
Antimicrobial Resistance (AMR) represents a serious threat to health and the
global economy. However, interest in antibacterial drug development has
decreased substantially in recent decades. Meanwhile, anti-virulence drug
development has emerged as an attractive alternative to fight AMR. Although
several macromolecular targets have been explored for this goal, their
druggability is a vital piece ... hiện toàn bộ
Antifungal Proteins from Plant LatexCurrent Protein and Peptide Science - Tập 21 Số 5 - Trang 497-506 - 2020
Mayck Silva Barbosa, Bruna da Silva Souza, Ana Clara Silva Sales, Jhoana D’arc Lopes de Sousa, Francisca Dayane Soares da Silva, Maria Gabriela Araújo Mendes, Káritta Raquel Lustoza da Costa, Taiane Maria de Oliveira, Tatiane Caroline Daboit, Jefferson Soares de Oliveira
Latex, a milky fluid found in several plants, is widely used for many purposes,
and its proteins have been investigated by researchers. Many studies have shown
that latex produced by some plant species is a natural source of biologically
active compounds, and many of the hydrolytic enzymes are related to health
benefits. Research on the characterization and industrial and pharmaceutical
utility of... hiện toàn bộ