Current Pediatrics Reports
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The Impact of Neonatal Illness on Nutritional Requirements: One Size Does Not Fit All
Current Pediatrics Reports - Tập 2 - Trang 248-254 - 2014
Sick neonates are at high risk for growth failure and poorer neurodevelopment than their healthy counterparts. The etiology of postnatal growth failure in sick infants is likely multi-factorial and includes undernutrition due to the difficulty of feeding them during their illness and instability. Illness also itself induces fundamental changes in cellular metabolism that appear to significantly al......
A Comprehensive, Multidisciplinary Approach to the Evaluation of the Neonatal Airway
Current Pediatrics Reports - Tập 7 Số 3 - Trang 107-115 - 2019
The Microbiome and its Impact on Disease in the Preterm Patient
Current Pediatrics Reports - - 2013
Emerging technologies derived largely from the Human Genome Project are applied to evaluating the intestinal microbiota in preterm infants. The microbial ecology of the developing intestine is highly related to health and disease, and new discoveries are emerging that will help us understand disorders in the development of the intestinal microbial ecosystem and how to eventually manipulate them to......
Lupus Nephritis: Novel Treatments and Diagnostic Approaches
Current Pediatrics Reports - Tập 1 - Trang 41-51 - 2012
Over the last decade, therapy for lupus nephritis in children has begun to shift from the provision of long-term steroids and intravenous cyclophosphamide to regimens with limited or no cyclophosphamide, lower steroid burdens, and increased reliance on oral mycophenolate mofetil. As the molecular immunology underlying the pathophysiology of lupus is further discerned, more targeted therapies, incl......
Pediatric to Adult Transition for Adolescents and Young Adults with Kidney Transplant
Current Pediatrics Reports - Tập 10 - Trang 155-163 - 2022
Adolescents and young adults with kidney transplant must graduate to adult care. Transition is a natural process; planned transition in this vulnerable population increases the probability of success. We describe the process, barriers to successful transition, and literature review on transition in children with kidney transplant. Many guidelines for a successful transition process exist in this p......
Atrial Septal Defect Device Closure in the Pediatric Population: A Current Review
Current Pediatrics Reports - Tập 3 - Trang 237-244 - 2015
Atrial septal defects are the most common congenital cardiac defects. The natural history of an uncorrected atrial septal defect causes a shortened life expectancy due to right ventricular volume overload and associated congestive heart failure, atrial arrhythmias, and/or pulmonary vascular disease. Surgical closure of the atrial septal defect is a procedure with a long-standing history, and the ......
Precocious Puberty and Its Treatment
Current Pediatrics Reports - Tập 1 - Trang 133-140 - 2013
Recent publications primarily relate to advances in central precocious puberty (CPP), with little new information concerning the diagnosis and treatment of peripheral precocious puberty (PPP). New information concerning CPP is centered on newer treatment options, all of which involve newer modes of delivering Gonadotropin-Releasing Hormone analog therapy. Recent publications about CPP and the asso......
Advances in the Evaluation and Management of Childhood Functional Abdominal Pain
Current Pediatrics Reports - Tập 6 - Trang 79-85 - 2018
Our objective is to review recent advances in the classification, evaluation, and management of children with functional abdominal pain. The Rome IV criteria allow the provider to identify whether a child’s presentation is consistent with a functional abdominal pain disorder. The concept of the multidimensional clinical profile acknowledges that multiple unique factors can contribute to a child’s ......
Necrotizing Enterocolitis in Preterm Infants is Related to Enteral Feeding, But the Mechanisms Remain Uncertain and Have Changed Over Time
Current Pediatrics Reports - Tập 2 - Trang 241-247 - 2014
Although the pathophysiology of necrotizing enterocolitis (NEC) remains incompletely understood, recent evidence supports the important role of aberrant bacterial colonization and activated pro-inflammatory signaling in the high-risk premature infant (Neu and Walker, N Engl J Med 364:255–264, 2011). Nonetheless, most clinicians surmise that enteral feeding significantly contributes to the initiati......
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