Current Molecular Medicine

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The Characteristics of Bax Inhibitor-1 and its Related Diseases
Current Molecular Medicine - Tập 14 Số 5 - Trang 603-615 - 2014
B Li, Raj Kumar Yadav, Gil Saeng Jeong, Hyung‐Ryong Kim, H-J Chae
Metformin and Energy Metabolism in Breast Cancer: From Insulin Physiology to Tumour-initiating Stem Cells
Current Molecular Medicine - Tập 10 Số 7 - Trang 674-691 - 2010
Alejandro Vázquez‐Martín, C. Oliveras-Ferraros, Sílvia Cufí, Begoña Martı́n-Castillo, Javier A. Menéndez
Combating the Progression of Novel Coronavirus SARS-CoV-2 Infectious Disease: Current State and Future Prospects in Molecular Diagnostics and Drug Discovery
Current Molecular Medicine - Tập 23 Số 2 - Trang 127-146 - 2023
Arbind Kumar, Aashish Sharma, Narendra Vijay Tirpude, Sharad Thakur, Sanjay Kumar
: A highly infectious and life-threatening virus was first reported in Wuhan, China, in late 2019, and it rapidly spread all over the world. This novel virus belongs to the coronavirus family and is associated with severe acute respiratory syndrome (SARS), causing respiratory disease known as COVID-19. In March 2020, WHO has declared the COVID-19 outbreak a global pandemic. Its morbidity and mortality rates are swiftly rising day by day, with the situation becoming more severe and fatal for the comorbid population. Many COVID-19 patients are asymptomatic, but they silently spread the infection. There is a need for proper screening of infected patients to prevent the epidemic transmission of disease and for early curative interventions to reduce the risk of developing severe complications from COVID-19. To date, the diagnostic assays are of two categories, molecular detection of viral genetic material by real-time RTpolymerase chain reaction and serological test, which relies on detecting antiviral antibodies. Unfortunately, there are no effective prophylactics and therapeutics available against COVID-19. However, a few drugs have shown promising antiviral activity against it, and these presently are being referred for clinical trials, albeit FDA has issued an Emergency Use Authorization (EUA) for the emergency use of a few drugs for SARSCoV- 2 infection. This review provides an insight into current progress, challenges and future prospects of laboratory detection methods of COVID-19, and highlights the clinical stage of the major evidence-based drugs/vaccines recommended against the novel SARS-CoV-2 pandemic virus.
Alpha 1 Anti-Trypsin: One Protein, Many Functions
Current Molecular Medicine - Tập 12 Số 7 - Trang 827-835 - 2012
James M. Hunt, Rubin M. Tuder
Molecular Mechanisms of Neurotoxicity of Pathological Prion Protein
Current Molecular Medicine - Tập 4 Số 4 - Trang 397-403 - 2004
Joaquı́n Castilla, Claudio Hetz, Claudio Soto
Muscarinic Receptors in Schizophrenia
Current Molecular Medicine - Tập 3 Số 5 - Trang 419-426 - 2003
Brian Dean, Frank P. Bymaster, Elizabeth Scarr
Transgenic Overproduction of Omega-3 Polyunsaturated Fatty Acids Provides Neuroprotection and Enhances Endogenous Neurogenesis After Stroke
Current Molecular Medicine - Tập 13 Số 9 - Trang 1465-1473 - 2013
Xiaoming Hu, Fan Zhang, Rehana K. Leak, W. Zhang, Masanori Iwai, R. A. Stetler, Yifan Dai, Allan Z. Zhao, Yanqin Gao, J. Chen
Mitochondrial Dysfunction and Glutamate Excitotoxicity Studied in Primary Neuronal Cultures
Current Molecular Medicine - Tập 4 Số 2 - Trang 149-177 - 2004
David G. Nicholls
Macrophage Response to Mycobacterium tuberculosis During HIV Infection Relationships Between Macrophage Activation and Apoptosis.
Current Molecular Medicine - Tập 1 Số 2 - Trang 209-216 - 2001
Abdelaziz Benjouad, Delia Goletti, Antonio Ciaramella, Angelo Martino, Vittorio Colizzi, Maurizio Fraziano
The Fatty Liver and Insulin Resistance
Current Molecular Medicine - Tập 5 Số 3 - Trang 287-295 - 2005
H Yki-Järvinen, Jukka Westerbacka
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