Current Colorectal Cancer Reports
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Liver-Directed Therapy for Metastatic Colon Cancer: Update
Current Colorectal Cancer Reports - Tập 18 - Trang 18-25 - 2022
To discuss the emerging technologies in the field of Interventional radiology (IR) for the management of metastatic colorectal cancer (mCRC). We review the field of selective internal radiation therapy (SIRT), and well-known IR treatments, with a more focused investigation of radioembolization with Yttrium-90 (Y-90). State-of-the-art treatment modalities for unresectable hepatic malignancies are c...... hiện toàn bộ
Conversion Chemotherapy for Unresectable Colorectal Liver Metastases: Are We Making a Difference?
Current Colorectal Cancer Reports - Tập 11 - Trang 160-167 - 2015
Surgical resection remains the only curative therapy for colorectal liver metastases (CLM) with 5-year survival rates ranging from 40 to 58 %. Unfortunately, only approximately 15–25 % of patients are eligible for initial surgical resection. Among those that are unresectable, response to chemotherapy can convert an additional 15–20 % of unresectable patients to a potentially resectable state and o...... hiện toàn bộ
Colorectal Cancer Screening: a North American Point of View
Current Colorectal Cancer Reports - Tập 12 - Trang 241-250 - 2016
Worldwide, colorectal cancer (CRC) is the third most commonly diagnosed cancer in males and second in females, with an estimated 1.4 million cases and 693,900 deaths in 2012. The current screening modalities utilized in the USA are examined in this review, along with current colonoscopy quality indicators. The contribution of CRC screening to the rising cost of health care in the USA has warranted...... hiện toàn bộ
Does Radiofrequency Ablation Add to Chemotherapy for Unresectable Liver Metastases?
Current Colorectal Cancer Reports - Tập 8 - Trang 130-137 - 2012
In patients with unresectable colorectal liver metastases (CRLM), radiofrequency ablation (RFA) might be a good alternative, whenever possible. In contrast to systemic therapy, the aim of RFA is to achieve complete local tumor control in an attempt to provide long-term survival. In this article we discuss the available evidence regarding the treatment of patients with unresectable CRLM, focusing o...... hiện toàn bộ
The Role of Adjuvant Treatment in Resected T3N0 Rectal Cancer
Current Colorectal Cancer Reports - - 2016
Intraoperative Radiation Therapy for Locally Advanced or Locally Recurrent Rectal Cancer
Current Colorectal Cancer Reports - Tập 13 - Trang 402-409 - 2017
Colorectal cancer is a major cause of morbidity and mortality across the world. Although surgery alone is very effective for patients with early stage disease, patients with more advanced disease required a combined modality approach. Standard doses of radiation therapy are usually ineffective in controlling localized disease that cannot be widely resected. Radiation dose escalation with intraoper...... hiện toàn bộ
A self-propelled colonoscope: Aer-O-Scope
Current Colorectal Cancer Reports - Tập 4 - Trang 10-13 - 2008
Screening for colorectal cancer by full colon imaging has major advantages for detection of precancerous polyps. Colonoscopy is not feasible in all settings and is undesirable in some because of its cost, risk, need for sedation, and limited capacity. The Aer-O-Scope (GI View Ltd.; Ramat Gan, Israel) is a self-propelled, diagnosis-only colonoscope. Its propulsion system utilizes two balloons, one ...... hiện toàn bộ
Molecular Markers of Chemotherapy Toxicity in Colorectal Cancer
Current Colorectal Cancer Reports - Tập 7 - Trang 105-111 - 2010
Personalized medicine appears to be the inevitable consequence of improvements in our understanding of the mechanisms of action of chemotherapeutic agents, as well as the description of the human genome and its impact on our understanding of the genes involved in DNA repair and drug metabolism. These rapid developments have been associated with the first efforts to establish genetic predictors of ...... hiện toàn bộ
Multidisciplinary Management of Rectal Cancer with Synchronous Resectable Liver Metastases
Current Colorectal Cancer Reports - Tập 13 - Trang 1-9 - 2017
Liver metastases are the most common manifestation of metastatic disease in colorectal cancer, and synchronous metastases occur in around 50% of patients. In rectal cancer, this presentation is uniquely challenging because of issues related to competing treatments and sequencing of therapy. Though there is published data on the management of rectal tumor and liver metastasis from colorectal cancer...... hiện toàn bộ
Animal Models to Test Adjuvant Treatment: An Experimental Model of Colon Cancer
Current Colorectal Cancer Reports - Tập 9 Số 3 - Trang 278-285 - 2013
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