Current Atherosclerosis Reports
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Preventing Diabetes and Atherosclerosis in the Cardiometabolic Syndrome
Current Atherosclerosis Reports - - 2021
Genome-Wide Association Studies of Coronary Artery Disease: Recent Progress and Challenges Ahead
Current Atherosclerosis Reports - Tập 20 - Trang 1-11 - 2018
Genome-wide association studies (GWAS) have been the primary tool for unbiased assessment of the genetic basis of coronary artery disease (CAD) for more than a decade. We summarize successes as well as shortcomings of recent studies in this context. The number of CAD-associated loci has more than doubled in the past year to 161. This rapid progress has been in large part due to the release of geno......
Controversies in the Use of Omega-3 Fatty Acids to Prevent Atherosclerosis
Current Atherosclerosis Reports - Tập 24 - Trang 571-581 - 2022
We discuss current controversies in the clinical use of omega-3 fatty acids (FA), primarily eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and examine discrepancies between recent trials. Furthermore, we discuss potential side effects reported in these studies and the role of mixed omega-3 FA dietary supplements and concerns about their use. REDUCE-IT showed that addition of icosapent......
Soy, garlic, and ginkgo biloba: Their potential role in cardiovascular disease prevention and treatment
Current Atherosclerosis Reports - Tập 5 - Trang 468-475 - 2003
There are hundreds of foods, nutrients, herbs, and botanicals that have “bioactive” constituents with potential human health benefits. Three of these are discussed in this review: soy, garlic, and ginkgo biloba. Each of these three choices involves an ingestible item composed of a complex mixture of bioactive agents. For each of these three, there is a large and growing body of research suggesting......
Current Concepts of the Role of Oxidized LDL Receptors in Atherosclerosis
Current Atherosclerosis Reports - Tập 14 Số 2 - Trang 150-159 - 2012
Oxidative stress and atherosclerosis
Current Atherosclerosis Reports - Tập 7 - Trang 242-248 - 2005
Understanding of the pathophysiology of atherosclerosis can provide new strategies for the prevention and treatment of patients with this common disease. Clinical, epidemiologic, and basic molecular science studies have identified oxidative stress as a factor contributing to the development and progression of atherosclerosis. Oxidative stress also participates in the pathogenesis of endothelial dy......
Psychosocial factors and coronary heart disease
Current Atherosclerosis Reports - Tập 6 - Trang 1-2 - 2004
Several recent observations support the notion of an independent role of psychosocial factors in the pathophysiology of CHD. More has to be learned about the mechanisms whereby these factors mediate its deleterious effects. Hopefully, more knowledge of this relationship may help us to discover new treatments for this ubiquitous disease.
Myocardial hibernation in coronary artery disease
Current Atherosclerosis Reports - Tập 4 - Trang 149-155 - 2002
Coronary artery disease (CAD) is very prevalent in Western societies and is a leading cause of mortality and morbidity. Despite decreases in mortality rates from CAD over the past 30 years, ischemic heart failure remains an important problem because people with CAD are now living longer. Hibernating myocardium may be defined as reversible left ventricular dysfunction due to chronic CAD that shows ......
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