Childhood Obesity and Cardiovascular Disease RiskCurrent Atherosclerosis Reports - Tập 25 - Trang 405-415 - 2023
Stephanie T. Chung, Andrea Krenek, Sheela N. Magge
The global epidemic of youth-onset obesity is tightly linked to the rising
burden of cardiometabolic disease across the lifespan. While the link between
childhood obesity and cardiovascular disease is established, this contemporary
review summarizes recent and novel advances in this field that elucidate the
mechanisms and impact of this public health issue. The review highlights the
emerging data ... hiện toàn bộ
The role of physical activity in maintaining a reduced weightCurrent Atherosclerosis Reports - Tập 9 - Trang 463-471 - 2008
Darcy L. Johannsen, Leanne M. Redman, Eric Ravussin
Current physical activity recommendations call for 30 minutes of
moderate-intensity activity on most days of the week, or the equivalent of
expending approximately 1000 kcal in activity per week. These recommendations
were formulated based on reducing the risk for chronic disease, but they do not
appear adequate for weight loss and maintenance. Data from epidemiologic studies
and randomized trials... hiện toàn bộ
Drug-eluting stents and vulnerable plaqueCurrent Atherosclerosis Reports - Tập 11 - Trang 146-148 - 2009
Mehmet Cilingiroglu, Faisal Khan
Coronary artery disease with acute coronary syndromes (ACS) is the leading cause
of death worldwide in both men and women. ACS mostly occur as a result of
rupture of “vulnerable plaque” with a superimposed thrombus formation, which
ultimately leads to distal cessation of blood flow. Vulnerable plaque mostly
occurs in mildly obstructive coronary lesions rather than severely stenosed (<
50%) lesions... hiện toàn bộ
Autophagy in atherosclerosisCurrent Atherosclerosis Reports - - 2008
Wim Martinet, Guido R. Y. De Meyer
Autophagy is a catabolic pathway for bulk destruction of long-lived proteins and
organelles via lysosomes. Basal autophagy represents a reparative,
life-sustaining process, but unrestrained autophagic activity promotes cell
death. A growing body of evidence suggests that autophagy occurs in advanced
atherosclerotic plaques. Vascular smooth muscle cells, macrophages, or
endothelial cells treated in... hiện toàn bộ
Impact of Different Doses of Omega-3 Fatty Acids on Cardiovascular Outcomes: a Pairwise and Network Meta-analysisCurrent Atherosclerosis Reports - Tập 22 - Trang 1-10 - 2020
Marco Lombardi, Juan G. Chiabrando, Giovanni M. Vescovo, Edoardo Bressi, Marco Giuseppe Del Buono, Salvatore Carbone, Rachel A. Koenig, Benjamin W. Van Tassell, Antonio Abbate, Giuseppe Biondi-Zoccai, Dave L. Dixon
Omega-3 fatty acid (O3FA) supplementation has shown conflicting evidence
regarding its benefit in cardiovascular events. We performed a pairwise and
network meta-analysis to elucidate the benefit of different doses of O3FA
supplementation in cardiovascular prevention. Fourteen studies were identified
providing data on 125,763 patients. A prespecified cut-off value of < 1 g per
day was set for low-... hiện toàn bộ
Antiplatelet Strategies for Secondary Prevention of Stroke and TIACurrent Atherosclerosis Reports - Tập 16 - Trang 1-9 - 2014
Koto Ishida, Steven R. Messé
Stroke is a major public health issue, and stroke recurrence accounts for a
quarter of all events. Antiplatelet therapy has been extensively studied for
secondary stroke prevention and is established as effective in this high-risk
population. Several agents have been evaluated in this setting, both in
isolation and combination. The most widely used antiplatelet medications are
aspirin, clopidogrel... hiện toàn bộ
The Interplay of Lipids, Lipoproteins, and Immunity in AtherosclerosisCurrent Atherosclerosis Reports - Tập 20 - Trang 1-9 - 2018
Angela Pirillo, Fabrizia Bonacina, Giuseppe Danilo Norata, Alberico Luigi Catapano
Atherosclerosis is an inflammatory disorder of the arterial wall, in which
several players contribute to the onset and progression of the disease. Besides
the well-established role of lipids, specifically cholesterol, and immune cell
activation, new insights on the molecular mechanisms underlying the atherogenic
process have emerged. Meta-inflammation, a condition of low-grade immune
response caus... hiện toàn bộ