Estimating outcomes and cost effectiveness using a single-arm clinical trial: ofatumumab for double-refractory chronic lymphocytic leukemiaCost Effectiveness and Resource Allocation - Tập 15 - Trang 1-8 - 2017
Anthony J. Hatswell, Gwilym J. Thompson, Penny A. Maroudas, Oleg Sofrygin, Thomas E. Delea
Ofatumumab (Arzerra®, Novartis) is a treatment for chronic lymphocytic leukemia refractory to fludarabine and alemtuzumab [double refractory (DR-CLL)]. Ofatumumab was licensed on the basis of an uncontrolled Phase II study, Hx-CD20-406, in which patients receiving ofatumumab survived for a median of 13.9 months. However, the lack of an internal control arm presents an obstacle for the estimation o...... hiện toàn bộ
Case management to improve adherence for HIV-infected patients receiving antiretroviral therapy in Ethiopia: a micro-costing studyCost Effectiveness and Resource Allocation - Tập 9 - Trang 1-8 - 2011
Elliot A Marseille, Sebastian Kevany, Ismael Ahmed, Getachew Feleke, Bill Graham, Thomas Heller, James G Kahn, Michael Reyes
Adherence to antiretroviral medication regimens is essential to good clinical outcomes for HIV-infected patients. Little is known about the costs of case management (CM) designed to improve adherence for patients identified as being at risk for poor adherence in resource-constrained settings. This study analyzed the costs, outputs, unit costs and correlates of unit cost variation for CM services i...... hiện toàn bộ
To what extent does recurrent government health expenditure in Uganda reflect its policy priorities?Cost Effectiveness and Resource Allocation - Tập 8 - Trang 1-7 - 2010
Frederick Mugisha, Juliet Nabyonga-Orem
The National Health Policy 2000 - 2009 and Health sector strategic plans I & II emphasized that Primary Health Care (PHC) would be the main strategy for national development and would be operationalized through provision of the minimum health care package. Commitment was to spend an increasing proportion of the health budget for the provision of the basic minimum package of health services which w...... hiện toàn bộ
Cost-utility of vitamin D supplementation to prevent acute respiratory infections in childrenCost Effectiveness and Resource Allocation - Tập 21 Số 1
Jefferson Antonio Buendía, Diana Guerrero Patiño
Abstract
Introduction
Increasing evidence has demonstrated the effectiveness and safety of vitamin D supplementation to prevent acute respiratory infections in children. More economic evaluations incorporating the new evidence and in the pediatric population are needed to know the efficiency of this...... hiện toàn bộ
Cost-analysis of different management policies for patients with mild hepatitis A virus infection in KazakhstanCost Effectiveness and Resource Allocation - Tập 3 - Trang 1-10 - 2005
Abdiaziz S Yassin, Michael Favorov, Edmond Maes, Ramses Sadek, Aliya Jumagulova, Victor Merker, Tatiana Surdina, Terence Chorba
For patients with mild hepatitis A virus (HAV) infection, this study compared estimates of total costs associated with managing cases under a policy of mandatory hospitalization in the Republic of Kazakhstan and estimates of total costs associated with managing cases in outpatient settings. Costs were estimated both from the perspective of the Ministry of Health and from a broader societal perspec...... hiện toàn bộ
Cost-effectiveness of abemaciclib plus endocrine therapy in high-risk HR+/HER2–early breast cancer in ChinaCost Effectiveness and Resource Allocation - Tập 21 - Trang 1-11 - 2023
Qiran Wei, YuTing Xu, Wei Liu, Xin Guan
The aim of this article is to evaluate the cost-effectiveness of abemaciclib plus endocrine therapy (ABE + ET) vs. ET as adjuvant treatment for high-risk hormone receptor-positive and human epidermal growth factor receptor 2-negative (HR+/HER2–) early breast cancer in China. From the perspective of the Chinese health care system, a 5-state Markov model was developed with a lifetime horizon. Data o...... hiện toàn bộ
Budget constraint and vaccine dosing: a mathematical modelling exerciseCost Effectiveness and Resource Allocation - Tập 12 - Trang 1-9 - 2014
Baudouin A Standaert, Desmond Curran, Maarten J Postma
Increasing the number of vaccine doses may potentially improve overall efficacy. Decision-makers need information about choosing the most efficient dose schedule to maximise the total health gain of a population when operating under a constrained budget. The objective of this study is to identify the most efficient vaccine dosing schedule within a fixed vaccination budget from a healthcare payer p...... hiện toàn bộ