Clinical and Translational Oncology
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SEOM guidelines for endometrial cancer
Clinical and Translational Oncology - Tập 14 - Trang 512-515 - 2012
Endometrial cancer (EC) is the most common gynaecological tumour in developing countries. Most patients with EC are diagnosed at an early stage with a low risk of relapse and overall survival at 5 years greater than 85%. Nevertheless, there is a subgroup of patients with a very poor prognosis due to the pathological features and molecular characteristics. Until now there has been no consensus rega...... hiện toàn bộ
Evidence mapping based on systematic reviews of therapeutic interventions for soft tissue sarcomas
Clinical and Translational Oncology - Tập 21 - Trang 1398-1412 - 2019
Soft tissue sarcomas are a heterogeneous group of rare tumours of mesenchymal origin. Evidence mapping is one of the most didactic and friendly approaches to organise and summarise the range of research activity in broad topic fields. The objective of this evidence mapping is to identify, describe and organise the current available evidence about therapeutic interventions on soft tissues sarcomas....... hiện toàn bộ
Exploration and analysis of differentially expressed genes in Epstein–Barr virus negative and positive plasmablastic lymphoma
Clinical and Translational Oncology - Tập 25 Số 10 - Trang 2884-2891
Predictive factors of trastuzumab-based chemotherapy in HER2 positive advanced gastric cancer: a single-center prospective observational study
Clinical and Translational Oncology - Tập 20 - Trang 695-702 - 2017
Trastuzumab plus chemotherapy is an effective therapy in HER2 positive advanced gastric cancer (AGC). However, the clinicopathologic factors that predict the outcome of routine trastuzumab therapy remain unclear. The outcome and safety profile of trastuzumab therapy in untreated HER2 positive AGC was evaluated in this prospective observational study. Clinical and pathological data including demogr...... hiện toàn bộ
Proteomic analysis of pleural effusion from lung adenocarcinoma patients by shotgun strategy
Clinical and Translational Oncology - - 2014
Unveiling the vulnerabilities of synthetic lethality in triple-negative breast cancer
Clinical and Translational Oncology - Tập 25 Số 11 - Trang 3057-3072
Comparisons of 5-aminolevulinic acid photodynamic therapy and after-loading radiotherapy in vivo in cervical cancer
Clinical and Translational Oncology - Tập 15 - Trang 434-442 - 2012
To compare the differences between 5-aminolevulinic acid photodynamic therapy (5-ALA-PDT) with traditional after-loading radiotherapy in aspects of efficacies and side effects. MTT assay was adopted to detect the inhibitive effects of 5-ALA-PDT on Hela cells proliferation. Flow cytometry was used to analyze cell apoptosis. After establishment of human cervical cancer xenograft model, the compariso...... hiện toàn bộ
Association of BRCA1 promoter methylation with rs11655505 (c.2265C>T) variants and decreased gene expression in sporadic breast cancer
Clinical and Translational Oncology - Tập 15 - Trang 555-562 - 2012
Breast cancer is the most common cancer and the main cause of cancer morbidity for women worldwide and is manifestation of abnormal genetic as well as epigenetic changes. Therefore, our aim was to study the association of BRCA1 promoter methylation with rs11655505 (c.−2265C/T) variants and gene expression in sporadic breast cancer. Twenty-nine sporadic breast cancer tissues and 26 normal biopsies ...... hiện toàn bộ
Overexpressed transcription factor FOXM1 is a potential diagnostic and adverse prognostic factor in postoperational gastric cancer patients
Clinical and Translational Oncology - Tập 16 Số 3 - Trang 307-314 - 2014
The role of plastic surgery in sarcoma treatment
Clinical and Translational Oncology - Tập 13 - Trang 102-108 - 2011
Sarcomas are low-incidence tumours, but their poor prognosis and complex treatment require the work of a multidisciplinary medical team. The Plastic Surgery Service forms part of the Sarcoma Functional Unit in our centre, performing tumour exeresis as well as immediate reconstruction. We present a retrospective study on the experience of the Plastic Surgery Service of the Hospital Universitario de...... hiện toàn bộ
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