Glutathione S-transferase, catalase, and mitochondrial superoxide dismutase gene polymorphisms modulate redox potential in systemic lupus erythematosus patients from Manaus, Amazonas, BrazilClinical Rheumatology - Tập 40 - Trang 3639-3649 - 2021
Marco Aurélio Almeida de Oliveira, Neila Hiraishi Mallmann, Giselle Katiane Bonfim Bacellar de Souza, Thiago de Jesus Bacha, Emerson Silva Lima, Domingos Sávio Nunes de Lima, Luiz Fernando de Souza Passos, Marilda de Souza Gonçalves, José Pereira de Moura Neto
To investigate the frequency of glutathione S-transferase (GST), catalase, and SOD2 genetic polymorphisms and their correlation with SLE. A total of 290 females (patients = 151; controls= 139) were recruited. Multiplex PCR was performed for genotyping GSTM1 and GSTT1 genes, whereas real-time qPCR was used for determination of SNPs: CAT C262T, SOD2 C47T, GSTP1 A313G and GSTP1 IVS6 -C16T. Thiol leve...... hiện toàn bộ
Prognostic factors of severe rheumatoid arthritisClinical Rheumatology - Tập 14 - Trang 19-21 - 1995
R. Westhovens
As one proposes sometimes more aggressive immunomodulatory treatment early in the process of rheumatoid arthritis, it becomes necessary to think about the prognostic factors early in the disease process that can predict eventual later poor outcome. We summarize the literature of the last 10 years dealing with this topic.
Successful treatment of refractory aortitis in antineutrophil cytoplasmic antibody-associated vasculitis using tocilizumabClinical Rheumatology - Tập 33 - Trang 287-289 - 2013
Kenchi Takenaka, Takehiko Ohba, Kozo Suhara, Yurie Sato, Kenji Nagasaka
A 47-year-old Japanese woman developed antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) complicated by a rare combination of aortitis and hypertrophic pachymeningitis. Despite the therapy with prednisolone and cyclophosphamide, the aortitis was not ameliorated. However, after cyclophosphamide was replaced with intravenous tocilizumab, the aortitis was improved, and the predni...... hiện toàn bộ
Left ventricular diastolic function evaluated with tissue Doppler imaging in children with familial Mediterranean feverClinical Rheumatology - Tập 28 - Trang 23-28 - 2008
Tamer Baysal, Harun Peru, Bulent Oran, Tahir Kemal Sahin, Yavuz Koksal, Sevim Karaaslan
The aim of this study was to assess the left ventricular diastolic function using conventional echocardiography and tissue Doppler imaging in children with familial Mediterranean fever. This study included 29 (13 males and 16 females) patients and 30 healthy subjects as controls. Body mass index was calculated and arterial blood pressure was monitored. After an overnight fast, venous blood samples...... hiện toàn bộ