Chronic Diseases and Translational Medicine
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Plasma RANTES level is correlated with cardio‐cerebral atherosclerosis burden in patients with ischemic cerebrovascular diseaseAbstract Background Regulated upon activation, normal T‐cell expressed, and secreted (RANTES) is a chemokine actively involved in the initiation and progression of atherosclerosis (AS), which is the major cause of ischemic cerebrovascular disease (ICVD). This study aimed to determine the associations between circulating RANTES level...
Chronic Diseases and Translational Medicine - Tập 6 - Trang 46-54 - 2020
The era of clinical application of gene diagnosis in cardiovascular diseases is comingAbstract Gene diagnosis refers to the use of genetic testing in the diagnosis of inheritable conditions, which has gradually been applied in clinical practice with the completion of the gene sequencing efforts of the Human Genome Project and the advancement of gene detection technology. In the specialty field of cardiology, monogenic cardiovascular diseases are defi... ...
Chronic Diseases and Translational Medicine - Tập 5 - Trang 214-220 - 2019
Lifestyle intervention for gestational diabetes mellitus prevention: A cluster‐randomized controlled studyAbstract Objective The study was to examine whether gestational diabetes mellitus (GDM) can be prevented by early trimester lifestyle counseling in a high‐risk population. Methods From September 2012 to January 2013, 1664 pregnancies in the Department of Obstetrics and Gyn...
Chronic Diseases and Translational Medicine - Tập 1 - Trang 169-174 - 2015
Cultural adaptation of the Michigan Hand Outcomes Questionnaire in patients with Carpal Tunnel Syndrome: A Turkish version studyAbstract Objective Cultural adaptations of the questionnaires are important for easy use. We aimed to assess the reliability and validity of the Turkish Version of the Michigan Hand Outcomes Questionnaire in patients with Carpal Tunnel Syndrome. Methods To assess test‐rete...
Chronic Diseases and Translational Medicine - Tập 1 - Trang 42-47 - 2015
Novel findings in relation to multiple anti‐atherosclerotic effects of XueZhiKang in humansAbstract Background Previous studies have clearly demonstrated that XueZhiKang (XZK), an extract of cholestin, can decrease low‐density lipoprotein cholesterol (LDL‐C) and cardiovascular events. However, the mechanism of the effects of XZK on atherosclerosis (AS) in humans has been reported less frequently. In the present study, we ...
Chronic Diseases and Translational Medicine - Tập 4 - Trang 117-126 - 2018
Identification of key genes and pathways in mild and severe nonalcoholic fatty liver disease by integrative analysisAbstract Background The global prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing. The pathogenesis of NAFLD is multifaceted, and the underlying mechanisms are elusive. We conducted data mining analysis to gain a better insight into the disease and to identify the hub genes associated with the progression of NAFLD....
Chronic Diseases and Translational Medicine - Tập 7 - Trang 276-286 - 2021
A questionnaire survey on the management of Graves' orbitopathy in China: A comparison with Europe and Latin‐AmericaAbstract Objective Management of Graves' orbitopathy (GO) continues to be a challenge to clinical endocrinologists. In the last few years, surveys on GO management have succeeded in elucidating trends in Europe and Latin America. To determine how endocrinologists in China assess and treat patients with GO and gain insight into how t...
Chronic Diseases and Translational Medicine - Tập 1 - Trang 117-123 - 2015
Thirdhand smoke: Genotoxicity and carcinogenic potentialAbstract Thirdhand smoke (THS), the residual tobacco smoke remaining in the environment after tobacco has been smoked, represents a hidden and underestimated public health hazard. Evidence supports its widespread presence in indoor environments. Exposure to secondhand smoke (SHS), a precursor of THS, has been well documented as a risk factor for human cancers, espec... ...
Chronic Diseases and Translational Medicine - Tập 6 - Trang 27-34 - 2020
Circulating free DNA in the era of precision oncology: Pre‐ and post‐analytical concernsAbstract Cancer treatment has entered the era of precision medicine, where knowledge of a patient's genetic profile is used to facilitate early diagnosis, drug selection, prognosis, prediction of drug responsiveness, the onset of secondary resistance, and relapse. Circulating free DNA (cfDNA) has emerged as an ideal source of genetic information for cancer patients,... ...
Chronic Diseases and Translational Medicine - Tập 2 - Trang 223-230 - 2016
Trend of non‐communicable disease mortality for three common conditions in the elderly population from 2002 to 2010: A population‐based study in ChinaAbstract Objective There is a lack of data focusing on non‐communicable disease (NCD) mortality in the Chinese elderly population over the past decade. Methods Using mortality data from the Chinese Health Statistics, we explored the crude and age‐standardized mortality tre...
Chronic Diseases and Translational Medicine - Tập 1 - Trang 152-157 - 2015
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