Chronic Diseases and Translational Medicine

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Cultural adaptation of the Michigan Hand Outcomes Questionnaire in patients with Carpal Tunnel Syndrome: A Turkish version study
Chronic Diseases and Translational Medicine - Tập 1 - Trang 42-47 - 2015
Ilker Ilhanli, Dilek Durmus, Gulhan Orekici
AbstractObjectiveCultural adaptations of the questionnaires are important for easy use. We aimed to assess the reliability and validity of the Turkish Version of the Michigan Hand Outcomes Questionnaire in patients with Carpal Tunnel Syndrome.MethodsTo assess test‐rete...... hiện toàn bộ
Thirdhand smoke: Genotoxicity and carcinogenic potential
Chronic Diseases and Translational Medicine - Tập 6 - Trang 27-34 - 2020
Bo Hang, Pin Wang, Yue Zhao, Hang Chang, Jian-Hua Mao, Antoine M. Snijders
AbstractThirdhand smoke (THS), the residual tobacco smoke remaining in the environment after tobacco has been smoked, represents a hidden and underestimated public health hazard. Evidence supports its widespread presence in indoor environments. Exposure to secondhand smoke (SHS), a precursor of THS, has been well documented as a risk factor for human cancers, espec...... hiện toàn bộ
Artificial intelligence: Neural network model as the multidisciplinary team member in clinical decision support to avoid medical mistakes
Chronic Diseases and Translational Medicine - Tập 2 - Trang 166-172 - 2016
Igor Vyacheslavovich Buzaev, Vladimir Vyacheslavovich Plechev, Irina Evgenievna Nikolaeva, Rezida Maratovna Galimova
AbstractObjectiveThe continuous uninterrupted feedback system is the essential part of any well‐organized system. We propose aLYNX concept that is a possibility to use an artificial intelligence algorithm or a neural network model in decision‐making system so as to avoid possible mistakes and to remind the doctors to review tactic...... hiện toàn bộ
Systemic treatment for hepatocellular carcinoma
Chronic Diseases and Translational Medicine - Tập 4 - Trang 148-155 - 2018
Manushi Aggarwal, Abeer Arain, Zhaohui Jin
AbstractHepatocellular carcinoma (HCC) is one of the most common cancers with high mortality worldwide. Treatment options for patients with advanced stage HCC remain a great challenge. However, novel agents especially small molecule tyrosine kinase inhibitor and innovative immunotherapy demonstrate new promising therapeutic options for these patients. This review a...... hiện toàn bộ
Intracranial artery stenosis: Current status of evaluation and treatment in China
Chronic Diseases and Translational Medicine - Tập 3 - Trang 197-206 - 2017
Bin Cai, Bin Peng
AbstractIntracranial artery stenosis (ICAS), a common cause of ischemic stroke, is a growing cause of concern in China. Recently, many epidemiological, etiological, pathophysiological, therapy, and diagnostic imaging studies have focused on ICAS, and guidelines and consensus on the diagnosis and treatment of ICAS have been published and updated by domestic experts....... hiện toàn bộ
Telomere shortening in patients on long‐term hemodialysis
Chronic Diseases and Translational Medicine - Tập 7 - Trang 266-275 - 2021
Yucheng Wang, Siyu Chen, Shi Feng, Cuili Wang, Hong Jiang, Song Rong, Haller Hermann, Jianghua Chen, Ping Zhang
AbstractBackgroundLeukocyte telomere length shortening is a characteristic of premature senescence, a process that can be accelerated by oxidative stress. In general, patients with end‐stage renal disease undergoing regular hemodialysis (HD) are repeatedly exposed to oxidative stress. Patients undergoing HD tend to have cardiovasc...... hiện toàn bộ
Data analysis in the post‐genome‐wide association study era
Chronic Diseases and Translational Medicine - Tập 2 - Trang 231-234 - 2016
Qiao-Ling Wang, Wen-Le Tan, Yan-Jie Zhao, Ming-Ming Shao, Jia-Hui Chu, Xu-Dong Huang, Jun Li, Ying-Ying Luo, Lin-Na Peng, Qiong-Hua Cui, Ting Feng, Jie Yang, Ya-Ling Han
AbstractSince the first report of a genome‐wide association study (GWAS) on human age‐related macular degeneration, GWAS has successfully been used to discover genetic variants for a variety of complex human diseases and/or traits, and thousands of associated loci have been identified. However, the underlying mechanisms for these loci remain largely unknown. To mak...... hiện toàn bộ
Effects of Jian Pi Qu Shi Formula on intestinal bacterial flora in patients with idiopathic membranous nephropathy: A prospective randomized controlled trial
Chronic Diseases and Translational Medicine - Tập 6 - Trang 124-133 - 2020
Rui Lang, Xin-Hui Wang, Ai-Feng Li, Ying Liang, Bao-Chen Zhu, Bin Shi, Yong-Qiu Zheng, Ren-Huan Yu
AbstractBackgroundThe incidence of idiopathic membranous nephropathy (IMN) has recently increased remarkably. Immune dysfunction caused by disordered intestinal flora might be an important factor affecting IMN. The Jian Pi Qu Shi Formula (JPQSF) shows promise in treating IMN. Here, we sequenced 16S rRNA genes to compare intestinal...... hiện toàn bộ
Role and mechanism of angiotensin‐converting enzyme 2 in acute lung injury in coronavirus disease 2019
Chronic Diseases and Translational Medicine - Tập 6 - Trang 98-105 - 2020
Meng-Yuan Liu, Bo Zheng, Yan Zhang, Jian-Ping Li
AbstractCoronavirus disease 2019 is a major threat to public health globally. Though its pathogenesis has not been fully elucidated, angiotensin‐converting enzyme 2 (ACE2) has been recently identified as a receptor for the entry of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) into the cell. Here, we aimed to clarify the potential role of ACE2 in SAR...... hiện toàn bộ
Ambient air quality and the risk for Chronic Obstructive Pulmonary Disease among Metro Manila Development Authority traffic enforcers in Metro Manila: An exploratory study
Chronic Diseases and Translational Medicine - Tập 7 Số 2 - Trang 117-124 - 2021
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