Chromosoma
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Scanning electron microscope analysis of structural changes and aberrations in human chromosomes associated with the inhibition and reversal of inhibition of ultraviolet light induced DNA repair
Chromosoma - Tập 96 - Trang 39-44 - 1987
Metaphase chromosomes appear decondensed in preparations from mitotic cells that have been irradiated with ultraviolet light (UV) and incubated with inhibitors of DNA synthesis; under these conditions DNA repair is inhibited and both single and double strand DNA breaks accumulate. After reversal of the inhibition chromosomes are condensed, but are often damaged. In this paper we show by scanning e......
Localization and characteristics of DNA underreplication zone in the 75C region of intercalary heterochromatin in Drosophila melanogaster polytene chromosomes
Chromosoma - - 2009
Localization of actin-related sequences by in situ hybridization to R-banded human chromosomes
Chromosoma - Tập 89 - Trang 163-167 - 1984
Using a cytoplasmic actin cDNA probe we have localized a number of actin sequences in the human genome using a novel in situ hybridization technique. Metaphase chromosomes treated to produce R-bands were directly annealed with 125I-labeled actin probe. Under these conditions many regions of the genome were apparently denatured enough to be capable of hybridizing with the probe. Most of the actin s......
The process of a Y-loss event in an XO/XO mammal, the Ryukyu spiny rat
Chromosoma - Tập 119 - Trang 519-526 - 2010
The Ryukyu spiny rat, Tokudaia osimensis, has an XO/XO sex chromosome constitution, lacking a Y chromosome and the mammalian sex-determining gene SRY. To investigate the Y-loss event, we traced three proto-Y-linked genes, RBMY1A1, EIF2S3Y, and KDM5D, in the genome. The original Y-linked RBMY1A1 was lost as well as SRY, and the remaining RBMY1A1 was a processed pseudogene on autosome. In contrast, ......
The labeling efficiency of human telomeres is increased by double-strand PRINS
Chromosoma - Tập 113 - Trang 204-209 - 2004
Telomeres are composed of tandem repeated sequences, TTAGGG, that can be detected either by fluorescence in situ hybridization (FISH), more efficiently by using a peptide nucleic acid (PNA) probe, or by the primed in situ (PRINS) technique. However, the efficiency of human telomere labeling using PRINS is somewhat lower than the efficiency using PNA-FISH. To solve this problem, we developed a doub......
Puffing in salivary gland chromosomes of picture-winged Hawaiian Drosophila
Chromosoma - Tập 41 - Trang 221-230 - 1973
A portion of the X chromosome was examined for puffing activity shortly before puparium formation in several species of Hawaiian Drosophila. A large puff was induced by incubating excised salivary glands with β ecdysone. In two of the seven species studied, the region in question has been moved by inversion to a new position relative to the banding sequence in the other species, but the reaction t......
In situ binding of AT-rich repetitive DNA to the centromeric heterochromatin in polytene chromosomes of chironomids
Chromosoma - - 1981
Pim-1 associates with protein complexes necessary for mitosis
Chromosoma - Tập 111 Số 2 - Trang 80-95 - 2002
Meiosis in autopolyploid Crepis capillaris
Chromosoma - Tập 102 - Trang 195-206 - 1993
Meiotic chromosome pairing of triploid and trisomic Crepis capillaris was analysed by electron microscopy in surface-spread prophase I nuclei and compared with light microscopic observations of metaphase I. This system allows identification and separate analysis of each chromosome of the C. capillaris genome. Prophase I trivalent frequencies are very high in all three trisomes and only slightly de......
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