Cell Stress and Chaperones

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Downstream caspases are novel targets for the antiapoptotic activity of the molecular chaperone Hsp70
Cell Stress and Chaperones - Tập 9 Số 3 - Trang 265 - 2004
Elena Y. Komarova, Elena Afanasyeva, Marina M. Bulatova, Michael E. Cheetham, Boris A. Margulis, Irina V. Guzhova
The involvement of homocysteine in stress-induced Aβ precursor protein misprocessing and related cognitive decline in rats
Cell Stress and Chaperones - Tập 21 - Trang 915-926 - 2016
Fang Xie, Yun Zhao, Jing Ma, Jing-Bo Gong, Shi-Da Wang, Liang Zhang, Xiu-Jie Gao, Ling-Jia Qian
Chronic stress is a risk factor in the development of cognitive decline and even Alzheimer’s disease (AD), although its underlying mechanism is not fully understood. Our previous data demonstrated that the level of homocysteine (Hcy) was significantly elevated in the plasma of stressed animals, which suggests the possibility that Hcy is a link between stress and cognitive decline. To test this hyp...... hiện toàn bộ
Development of rapid and highly sensitive HSPA1A promoter-driven luciferase reporter system for assessing oxidative stress associated with low-dose photodynamic therapy
Cell Stress and Chaperones - Tập 18 - Trang 203-213 - 2012
Yuanhong Zheng, Vanminh Le, Zhuoan Cheng, Sheng Xie, Hegeng Li, Jianhui Tian, Jianwen Liu
Photodynamic therapy (PDT) is a regulatory-approved modality for treating a variety of malignant tumors. It induces tumor tissue damage via photosensitizer-mediated oxidative cytotoxicity. The heat shock protein 70 (HSP70-1) is a stress protein encoded by the HSPA1A gene and is significantly induced by oxidative stress associated with PDT. The aim of this study was to identify the functional regio...... hiện toàn bộ
Serum levels of HSP70 and other DAMP proteins can aid in patient diagnosis after traumatic injury
Cell Stress and Chaperones - Tập 21 Số 4 - Trang 677-686 - 2016
Baizhao Ren, Guoying Zou, Yiran Huang, Guofeng Xu, Fei Xu, Junyu He, Hongli Zhu, Ping Yu
Unfolding the complexities of ER chaperones in health and disease: report on the 11th international calreticulin workshop
Cell Stress and Chaperones - Tập 20 - Trang 875-883 - 2015
Leslie Gold, David Williams, Jody Groenendyk, Marek Michalak, Paul Eggleton
The 11th International Calreticulin workshop was held May 15–18, 2015 at New York University School of Medicine-Langone Medical Center, New York. The meeting highlighted many of the new discoveries in the past 2 years involving the important role of molecular chaperones in physiological and pathological processes. Crucial to the understanding of these disease processes was the role of chaperones i...... hiện toàn bộ
Choosing an appropriate glucose concentration according to different cell types and experimental purposes is very important
Cell Stress and Chaperones - - 2015
Yan Huang, Zhi‐Gang Xiong
The expression of DAMP proteins HSP70 and cancer-testis antigen SPAG9 in peripheral blood of patients with HCC and lung cancer
Cell Stress and Chaperones - Tập 22 - Trang 237-244 - 2016
Biqiong Ren, Shudi Luo, Fei Xu, Guoying Zou, Guofeng Xu, Junyu He, Yiran Huang, Haowen Zhu, Yong Li
There are different views of how the immune system participates in the reaction to cancer. Here, we evaluated expression of DAMP proteins HSP70 and cancer-testis antigen SPAG9 in patients with hepatocellular carcinoma (HCC) and lung cancer to explore tumor immunity. Our analysis showed that levels of HSP70 and SPAG9 antibody were significantly higher in the serum of lung cancer and HCC patients th...... hiện toàn bộ
Guidelines for the nomenclature of the human heat shock proteins
Cell Stress and Chaperones - Tập 14 - Trang 105-111 - 2008
Harm H. Kampinga, Jurre Hageman, Michel J. Vos, Hiroshi Kubota, Robert M. Tanguay, Elspeth A. Bruford, Michael E. Cheetham, Bin Chen, Lawrence E. Hightower
The expanding number of members in the various human heat shock protein (HSP) families and the inconsistencies in their nomenclature have often led to confusion. Here, we propose new guidelines for the nomenclature of the human HSP families, HSPH (HSP110), HSPC (HSP90), HSPA (HSP70), DNAJ (HSP40), and HSPB (small HSP) as well as for the human chaperonin families HSPD/E (HSP60/HSP10) and CCT (TRiC)...... hiện toàn bộ
Autophagy inhibition by biotin elicits endoplasmic reticulum stress to differentially regulate adipocyte lipid and protein synthesis
Cell Stress and Chaperones - Tập 24 - Trang 343-350 - 2019
Senthilraja Selvam, Anand Ramaian Santhaseela, Dhasarathan Ganesan, Sudarshana Rajasekaran, Tamilselvan Jayavelu
Biotin is an indispensable adipogenic agent, and its ability to coordinate carbohydrate, lipid, and amino acid metabolism sensitizes insulin signaling in adipocytes. This enables the organism to adapt and survive under nutrient stress by synthesis and storage of lipids. Biotin deficiency mimics insulin resistance with alterations in cellular intermediary metabolism. Though the mechanism of lipogen...... hiện toàn bộ
Expression status of heat shock proteins in response to cold, heat, or insecticide exposure in the Colorado potato beetle Leptinotarsa decemlineata
Cell Stress and Chaperones - Tập 24 - Trang 539-547 - 2019
Pascal Dumas, Mathieu D. Morin, Sébastien Boquel, Chandra E. Moffat, Pier Jr Morin
The Colorado potato beetle (Leptinotarsa decemlineata (Say)) is an agricultural pest that threatens the potato industry worldwide. This insect is widely regarded as one of the most difficult-to-control pests, as it can thrive in a wide range of temperature conditions and routinely develops resistance towards various insecticides. The molecular changes associated with response to these challenges h...... hiện toàn bộ
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