Morphofunctional Characteristics of the Immune System in CBA and C57Bl/6g MiceBulletin of Experimental Biology and Medicine - Tập 150 - Trang 725-728 - 2011
V. A. Shkurupiy, V. O. Tkachev, O. V. Potapova, N. G. Luzgina, J. S. Bugrimova, K. S. Obedinskaya, N. S. Zaiceva, A. V. Chechushkov
We studied peculiarities of morphofunctional organization of the immune system in C57Bl/6g and CBA mice differing by their susceptibility to various types of infectious agents. The revealed differences in the structure of lymphoid organs, T lymphocyte subpopulation ratio and their differentiation into Th1/Th2 cells after mitogen stimulation drove us to a conclusion on genetically determined regula...... hiện toàn bộ
Status of Free-Radical Oxidation and Proliferation Processes in Patients with Atopic Dermatitis and Lichen PlanusBulletin of Experimental Biology and Medicine - Tập 150 - Trang 690-692 - 2011
S. G. Sapuntsova, O. A. Lebed’ko, M. V. Shchetkina, M. Yu. Fleyshman, E. A. Kozulin, S. S. Timoshin
We studied the status of proliferation processes (by Ki-67 expression) and biogenesis of free radicals (by chemiluminescence method) in skin biopsy specimens from patients with atopic dermatitis and lichen planus. The index of Ki-67-positive nuclei significantly (p<0.05) increased to 28.40±2.00% in patients with dermatitis and to 32.6±1.9% in patients with lichen planus vs. 8.65±1.31% in the refer...... hiện toàn bộ
Morphological Changes in the Brain of Mice with Systemic Candidiasis Treated with Composition of Amphotericin B and Oxidized DextranBulletin of Experimental Biology and Medicine - Tập 151 - Trang 95-98 - 2011
V. A. Shkurupiy, E. V. Guseva, O. V. Potapova, A. P. Nadeev
We observed morphological manifestation of encephalitis 3, 7, 10 and 28 days after intravenous infection of adult male CBA mice with Candida albicans. Compounds were administered intraperitoneally every other day starting from the next day postinfection. Untreated animals (100%) died over the period between days 18 and 20 postinfection; 60% animals receiving oxidized dextran alone survived by day ...... hiện toàn bộ
Involvement of Autonomic Nervous System in Antiarrhythmic Effect of Intermittent Hypobaric HypoxiaBulletin of Experimental Biology and Medicine - Tập 163 - Trang 299-301 - 2017
N. V. Naryzhnaya, A. V. Mukhamedzyanov, T. V. Lasukova, L. N. Maslov
We studied the involvement of the autonomic nervous system in the antiarrhythmic effect of intermittent hypobaric hypoxia modeled by daily placing the rats into an altitude chamber at 405 mm Hg (5000 m above sea level). The antiarrhythmic effect of hypoxia was observed on the model of acute coronary occlusion/reperfusion in vivo, but not during simulation of total ischemia/reperfusion of the isola...... hiện toàn bộ
Effect of HLA-compatibility in married couples on the development and severity of gestosisBulletin of Experimental Biology and Medicine - Tập 143 - Trang 222-224 - 2007
G. T. Sukhikh, R. A. Nurutdinova, L. E. Murashko, L. Z. Faizullin
We studied the effect of histocompatibility in married couples on the development and severity of gestosis. It was found that gestosis more often develops in women with two common HLA alleles of class II major histocompatibility complex with her husband. The greatest number of coincidences was detected in subgroups with medium and severe gestosis. Perinatal outcomes in women with medium-severe ges...... hiện toàn bộ