British Journal of Ophthalmology
1468-2079
0007-1161
Anh Quốc
Cơ quản chủ quản: BMJ Publishing Group
Lĩnh vực:
Cellular and Molecular NeuroscienceOphthalmologySensory Systems
Phân tích ảnh hưởng
Thông tin về tạp chí
The British Journal of Ophthalmology (BJO) is an international peer-reviewed journal for ophthalmologists and visual science specialists describing clinical investigations, clinical observations, and clinically relevant laboratory investigations related to ophthalmology. Main features include articles on both clinical and laboratory sciences, up to date major reviews, editorials, education articles and letters. There are sections for "Innovations" and "Global issues" where surgical, diagnositic and therapeutic innovations and manuscripts of regional interest to geographic areas of the world respectively, are published.
Các bài báo tiêu biểu
High dose rate and low dose rate ruthenium brachytherapy for uveal melanoma. No association with ocular outcome
Tập 98 Số 10 - Trang 1349-1354 - 2014
Prognosis of choroidal melanoma and the result of ruthenium brachytherapy combined with transpupillary thermotherapy in Korean patients
Tập 97 Số 5 - Trang 653-658 - 2013
Predicting local control of choroidal melanomas following 106Ru plaque brachytherapy
Tập 95 Số 2 - Trang 166-170 - 2011
Ruthenium-106 versus iodine-125 plaque brachytherapy of 571 choroidal melanomas with a thickness of ≥5.5 mm Background Episcleral brachytherapy is the most common eye-preserving treatment for medium-sized choroidal melanomas. γ-emitting iodine-125 (125 I) and β-emitting ruthenium-106 (106 Ru) are widely used. The latter is however generally reserved for thinner tumours (<6 mm). In this study, we compare ocular and patient survival in thicker tumours treated with the respective radioisotope. Methods All patients with ≥5.5 mm thick choroidal melanomas who were treated with plaque brachytherapy at a single institution between 1 November 1979 and 31 December 2015 were included (n=571). Size-controlled Cox regression HRs for postbrachytherapy enucleation, repeated brachytherapy and melanoma-related mortality were calculated, as well as Kaplan-Meier disease-specific survival and relative 10-year survival in matched subgroups. Results 317 patients were treated with 106 Ru and 254 with 125 I. The rate of repeated brachytherapy was significantly higher among patients treated with 106 Ru (8%) than with 125 I (1%, p<0.001). Size-controlled Cox regression HRs for postbrachytherapy enucleation (125 I vs 106 Ru 0.7, p=0.083) and melanoma-related mortality were not significant (125 I vs 106 Ru 1.1, p=0.63). Similarly, Kaplan-Meier disease-specific and relative 10-year survival was comparable in matched groups of 5.5–7.4 mm (relative survival 106 Ru 59%, 125 I 56%) and ≥7.5 mm thick tumours (relative survival 106 Ru 46%, 125 I 44%). Conclusions Rates of repeated brachytherapy were significantly higher among patients treated with 106 Ru versus 125 I for thick choroidal melanomas. There were, however, no significant differences in rates of enucleation or patient survival.
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Episcleral brachytherapy of uveal melanoma: role of intraoperative echographic confirmation
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Brachytherapy and endoresection for choroidal melanoma: a cohort study
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Ruthenium-106 plaque brachytherapy for thick posterior uveal melanomas
Tập 93 Số 9 - Trang 1167-1171 - 2009
Posterior subcapsular cataracts and glaucoma associated with long-term oral corticosteroid therapy. In patients with rheumatoid arthritis and related conditions.
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Incidence and severity of keratoconus in Asir province, Saudi Arabia
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