Breast Cancer
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The efficacy and feasibility of dose-dense sequential chemotherapy for Japanese patients with breast cancer
Breast Cancer - Tập 25 - Trang 717-722 - 2018
Perioperative dose-dense chemotherapy (DDCT) with granulocyte-colony stimulating factor (G-CSF) prophylaxis is a standard treatment for patients with high-risk breast cancer. The approval of this approach in Japan led to the widespread adoption of DDCT, despite limited efficacy and safety data among Japanese patients. We evaluated the efficacy and safety of neoadjuvant DDCT for Japanese patients w......
Correction to: Validation of a nuclear grading system for resected stage I–IIIA, high-risk, node-negative invasive breast carcinoma in the N·SAS-BC 01 trial
Breast Cancer - Tập 29 Số 4 - Trang 730-730 - 2022
Benefits of using the cell block method to determine the discordance of the HR/HER2 expression in patients with metastatic breast cancer
Breast Cancer - Tập 23 - Trang 633-639 - 2015
The discordance of the hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) expressions between primary cancer and metastatic lesions is an important issue when selecting the optimal treatments for patients with metastatic breast cancer. A rebiopsy for the metastatic cancer is recommended before selecting the treatment; however, it is not easy to take a tissue sample for all m......
Association of molecular subtypes and treatment with survival in invasive micropapillary breast cancer: an analysis of the Surveillance, Epidemiology, and End Results database
Breast Cancer - - Trang 1-12 - 2023
This study aims to examine the features, treatments, and survival of invasive micropapillary carcinoma (IMPC) according to different molecular subtypes. In this cohort study, data between 2010 and 2018 were retrospectively reviewed from the Surveillance, Epidemiology, and End Results database. Molecular subtypes were categorized into four varieties: hormone receptor (HR)+/HER2− (Luminal A), HR+/HE......
Sentinel lymph node biopsy in patients with breast cancer using superparamagnetic iron oxide and a magnetometer
Breast Cancer - Tập 20 - Trang 223-229 - 2012
Some hospitals lack facilities for radioisotopes in sentinel node biopsy. A novel method is used with a superparamagnetic tracer and a magnetometer instead of a radioisotope. Thirty patients were included in the study after obtaining IRB approval. Superparamagnetic iron oxide and patent blue dye were injected in the subareolar breast tissue. Following a few minutes of massage to promote migration ......
Morphological characteristics of basal-like subtype of breast carcinoma with special reference to cytopathological features
Breast Cancer - Tập 16 - Trang 179-185 - 2009
Expression profiling of invasive breast carcinomas by DNA microarray techniques has identified five distinct subtypes of tumors (luminal A, luminal B, normal breast-like, HER2 overexpression, and basal-like) that are associated with different clinical outcomes and with different chemotherapy. Basal-like carcinoma is associated with younger patient age, high histological grade, aggressive clinical ......
Simultaneous comparison between strain and shear wave elastography of breast masses for the differentiation of benign and malignant lesions by qualitative and quantitative assessments
Breast Cancer - Tập 26 - Trang 792-798 - 2019
To compare the addition of diagnostic strain elastography (SE) and shear wave elastography (SWE) values to the conventional B-mode ultrasonography in differentiating between benign and malignant breast masses by qualitative and quantitative assessments. B-mode ultrasound, SE, and SWE were simultaneously performed using one ultrasound system in 148 breast masses; 88 of them were malignant. The brea......
Apogossypolone induces autophagy and apoptosis in breast cancer MCF-7 cells in vitro and in vivo
Breast Cancer - Tập 21 - Trang 223-230 - 2012
Apogossypolone (ApoG2), a new derivative of gossypol, is a potent cell-growth inhibitor. ApoG2 has been demonstrated to have superior anti-tumor activity than gossypol in Bcl-2 transgenic mice. The purpose of this study was to investigate the inhibitory effect of ApoG2 on breast cancer cell line MCF-7 in vitro and in vivo, and to investigate its anti-tumor mechanism. MCF-7 cell line in culture was......
Pathological lymph node involvement at surgery is a significant predictive factor of recurrence in locally advanced breast cancer treated with concomitant epirubicin–docetaxel neoadjuvant chemotherapy: a cohort study
Breast Cancer - Tập 16 Số 1 - Trang 42-48 - 2009
Ti Breast Cancer Associated with Von Recklinghausen’s Neurofibromatosis
Breast Cancer - Tập 6 - Trang 227-230 - 1999
A rare case of breast cancer associated with von Recklinghausen’s neurofibromatosis is reported. This case and review of the literature illustrate the problems of clinical diagnosis. A 66-year-old woman who had undergone sigmoidectomy for sigmoid colon cancer two years previously, was admitted to the hospital because of a left breast skin retraction in October, 1998. The patient had von Recklingha......
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