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Changes in transmission across synapses of Ia afferents in spastic patients
Brain - Tập 118 Số 4 - Trang 995-1004 - 1995
Jens Bo Nielsen, N. Petersen, C Crone
Modulation of presynaptic inhibition and disynaptic reciprocal Ia inhibition during voluntary movement in spasticity
Brain - Tập 124 Số 4 - Trang 826-837 - 2001
Hiroshi Morita, C Crone, D Christenhuis, N. Petersen, Jens Bo Nielsen
Evidence for label-retaining tumour-initiating cells in human glioblastoma
Brain - Tập 134 Số 5 - Trang 1331-1343 - 2011
Loic P. Deleyrolle, Angus Harding, Kathleen Cato, Florian A. Siebzehnrübl, Maryam Rahman, Hassan Azari, Sarah Olson, Brian Gabrielli, Geoffrey W. Osborne, Angelo L. Vescovi, Brent A. Reynolds
CYP7B1 mutations in pure and complex forms of hereditary spastic paraplegia type 5
Brain - Tập 132 Số 6 - Trang 1589-1600 - 2009
Cyril Goizet, A. Boukhris, A. Dürr, Christian Beetz, Jérémy Truchetto, Christelle Tesson, Maria K. Tsaousidou, Sylvie Forlani, Lucie Guyant‐Maréchal, B. Fontaine, João Tiago Guimarães, Bertrand Isidor, O. Chazouillères, Dominique Wendum, D. Grid, Françoise Chevy, Patrick F. Chinnery, Paula Coutinho, Jean‐Philippe Azulay, Imed Feki, Fanny Mochel, Francesco Visioli, Chokri Mhiri, Andrew H. Crosby, Alexis Brice, Giovanni Stevanin
Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease
Brain - Tập 131 Số 11 - Trang 2851-2859 - 2008
Valerio Leoni, Caterina Mariotti, Sarah J. Tabrizi, Marta Valenza, Edward J. Wild, Susie M.D. Henley, Nicola Z. Hobbs, Maria Luisa Mandelli, Marina Grisoli, Ingemar Björkhem, Elena Cattaneo, Stefano Di Donato
Intracellular phospholipase A2 group IVA and group VIA play important roles in Wallerian degeneration and axon regeneration after peripheral nerve injury
Brain - Tập 131 Số 10 - Trang 2620-2631 - 2008
Rubèn López‐Vales, Xavier Navarro, Takao Shimizu, Constantinos Baskakis, George Kokotos, Violetta Constantinou‐Kokotou, Daren Stephens, Edward A. Dennis, Samuel David
KONZO, AN EPIDEMIC UPPER MOTOR NEURON DISEASE STUDIED IN TANZANIA
Brain - Tập 113 Số 1 - Trang 223-235 - 1990
William P. Howlett, G. Brubaker, N. Mlingi, Hans Rosling
The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings
Brain - Tập 143 Số 10 - Trang 3104-3120 - 2020
Ross W. Paterson, Rachel Brown, Laura Benjamin, Ross Nortley, Sarah Wiethoff, Tehmina Bharucha, Dipa Jayaseelan, Guru Kumar, Rhian Raftopoulos, L. Zambreanu, Vinojini Vivekanandam, Anthony Khoo, Ruth Geraldes, Krishna Chinthapalli, Elena Boyd, Hatice Tuzlalı, Gary Price, Gerry Christofi, Jasper M. Morrow, Patricia McNamara, Benjamin C. Mcloughlin, Soon Tjin Lim, Puja R. Mehta, Viva Levee, Stephen Keddie, Wisdom Yong, S. Anand Trip, Alexander Foulkes, Gary Hotton, Thomas D. Miller, Alex Everitt, Christopher Carswell, Nicholas Davies, Michael Yoong, David Attwell, Jemeen Sreedharan, Eli Silber, Thomas K. Karikari, Arvind Chandratheva, Richard Perry, Robert Simister, Anna M. Checkley, Nicky Longley, Simon F. Farmer, Francesco Carletti, Catherine Houlihan, Maria Thom, Michael P. Lunn, Jennifer Spillane, Robin Howard, Angela Vincent, David J. Werring, Chandrashekar Hoskote, Hans Rolf Jäger, Hadi Manji, Michael S. Zandi
Abstract Preliminary clinical data indicate that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with neurological and neuropsychiatric illness. Responding to this, a weekly virtual coronavirus disease 19 (COVID-19) neurology multi-disciplinary meeting was established at the National Hospital, Queen Square, in early March 2020 in order to discuss and begin to understand neurological presentations in patients with suspected COVID-19-related neurological disorders. Detailed clinical and paraclinical data were collected from cases where the diagnosis of COVID-19 was confirmed through RNA PCR, or where the diagnosis was probable/possible according to World Health Organization criteria. Of 43 patients, 29 were SARS-CoV-2 PCR positive and definite, eight probable and six possible. Five major categories emerged: (i) encephalopathies (n = 10) with delirium/psychosis and no distinct MRI or CSF abnormalities, and with 9/10 making a full or partial recovery with supportive care only; (ii) inflammatory CNS syndromes (n = 12) including encephalitis (n = 2, para- or post-infectious), acute disseminated encephalomyelitis (n = 9), with haemorrhage in five, necrosis in one, and myelitis in two, and isolated myelitis (n = 1). Of these, 10 were treated with corticosteroids, and three of these patients also received intravenous immunoglobulin; one made a full recovery, 10 of 12 made a partial recovery, and one patient died; (iii) ischaemic strokes (n = 8) associated with a pro-thrombotic state (four with pulmonary thromboembolism), one of whom died; (iv) peripheral neurological disorders (n = 8), seven with Guillain-Barré syndrome, one with brachial plexopathy, six of eight making a partial and ongoing recovery; and (v) five patients with miscellaneous central disorders who did not fit these categories. SARS-CoV-2 infection is associated with a wide spectrum of neurological syndromes affecting the whole neuraxis, including the cerebral vasculature and, in some cases, responding to immunotherapies. The high incidence of acute disseminated encephalomyelitis, particularly with haemorrhagic change, is striking. This complication was not related to the severity of the respiratory COVID-19 disease. Early recognition, investigation and management of COVID-19-related neurological disease is challenging. Further clinical, neuroradiological, biomarker and neuropathological studies are essential to determine the underlying pathobiological mechanisms that will guide treatment. Longitudinal follow-up studies will be necessary to ascertain the long-term neurological and neuropsychological consequences of this pandemic.
Anti-Hu-associated paraneoplastic encephalomyelitis: analysis of 200 patients
Brain - Tập 124 Số 6 - Trang 1138-1148 - 2001
Francesc Graus
Progressive non-fluent aphasia is associated with hypometabolism centred on the left anterior insula
Brain - Tập 126 Số 11 - Trang 2406-2418 - 2003
Peter J. Nestor
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