Cerebellar neuromodulation improves naming in post-stroke aphasia Tập 2 Số 2 - 2020
Rajani Sebastian, Ji Hyun Kim, Rachel Brenowitz, Donna Tippett, John E. Desmond, Pablo Celnik, Argye E. Hillis
AbstractTranscranial direct current stimulation has been shown to increase the
efficiency of language therapy in chronic aphasia; however, to date, an optimal
stimulation site has not been identified. We investigated whether
neuromodulation of the right cerebellum can improve naming skills in chronic
aphasia. Using a randomized, double-blind, sham-controlled, within-subject
crossover study design,... hiện toàn bộ
Evaluation of [18F]PI-2620, a second-generation selective tau tracer, for assessing four-repeat tauopathies Tập 3 Số 4 - 2021
Toshiki Tezuka, Keisuke Takahata, Morinobu Seki, Hajime Tabuchi, Yuki Momota, Mika Shiraiwa, Natsumi Suzuki, Ayaka Morimoto, Tadaki Nakahara, Yu Iwabuchi, Eisuke Miura, Yasuharu Yamamoto, Yasunori Sano, Kei Funaki, Bun Yamagata, Ryo Ueda, Takahito Yoshizaki, Kyoko Mashima, Mamoru Shibata, Munenori Oyama, Kensuke Okada, Masahito Kubota, Hajime Okita, Masaki Takao, Masahiro Jinzaki, Jin Nakahara, Masaru Mimura, Daisuke Ito
Abstract Tau aggregates represent a key pathologic feature of Alzheimer’s
disease and other neurodegenerative diseases. Recently, PET probes have been
developed for in vivo detection of tau accumulation; however, they are limited
because of off-target binding and a reduced ability to detect tau in
non-Alzheimer’s disease tauopathies. The novel tau PET tracer, [18F]PI-2620, has
a high binding affin... hiện toàn bộ
Long-term motor deficit in brain tumour surgery with preserved intra-operative motor-evoked potentials Tập 3 Số 1 - 2021
Davide Giampiccolo, Cristiano Parisi, Pietro Meneghelli, Vincenzo Tramontano, Federica Basaldella, M. Pasetto, Giampietro Pinna, Luigi Cattaneo, Francesco Sala
Abstract Muscle motor-evoked potentials are commonly monitored during brain
tumour surgery in motor areas, as these are assumed to reflect the integrity of
descending motor pathways, including the corticospinal tract. However, while the
loss of muscle motor-evoked potentials at the end of surgery is associated with
long-term motor deficits (muscle motor-evoked potential-related deficits), there
is... hiện toàn bộ
Exploring white matter functional networks in children with attention-deficit/hyperactivity disorder Tập 2 Số 2 - 2020
Xuan Bu, Kaili Liang, Qingxia Lin, Yingxue Gao, Andan Qian, Hong Chen, Wanying Chen, Meihao Wang, Chuang Yang, Xiaoqi Huang
AbstractAttention-deficit/hyperactivity disorder has been identified to involve
the impairment of large-scale functional networks within grey matter, and recent
studies have suggested that white matter, which also encodes neural activity,
can manifest intrinsic functional organization similar to that of grey matter.
However, the alterations in white matter functional networks in
attention-deficit/... hiện toàn bộ
APOE ε4 alters associations between docosahexaenoic acid and preclinical markers of Alzheimer’s disease Tập 3 Số 2 - 2021
Gillian Coughlan, Ryan Larsen, Min Kim, David White, Rachel Gillings, Michael A. Irvine, Andrew Scholey, Neal J. Cohen, Cristina Legido‐Quigley, Michael Hornberger, Anne Marie Minihane
Abstract Docosahexaenoic acid is the main long-chain omega-3 polyunsaturated
fatty acids in the brain and accounts for 30−40% of fatty acids in the grey
matter of the human cortex. Although the influence of docosahexaenoic acid on
memory function is widely researched, its association with brain volumes is
under investigated and its association with spatial navigation is virtually
unknown. This is ... hiện toàn bộ
Epileptic discharges initiate from brain areas with elevated accumulation of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors Tập 4 Số 2 - 2022
Tomoyuki Miyazaki, Yutaro Takayama, Masaki Iwasaki, Mai Hatano, Waki Nakajima, Naoki Ikegaya, Tetsuya Yamamoto, Shohei Tsuchimoto, Hiroki Kato, Takuya Takahashi
AbstractPresurgical identification of the epileptogenic zone is a critical
determinant of seizure control following surgical resection in epilepsy.
Excitatory glutamate α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid
receptor is a major component of neurotransmission. Although elevated
α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor levels are
observed in surgically resected b... hiện toàn bộ