Biopolymers

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

Sắp xếp:  
One hundred‐fold acceleration of DNA renaturation rates in solution
Biopolymers - Tập 20 Số 7 - Trang 1537-1547 - 1981
Robert Wieder, James G. Wetmur
AbstractSolvents which accelerate DNA renaturation rates have been investigated. Addition of NaCl or LiCl to DNA in 2.4M Et4NCl initially increases renaturation rates at 45°C and then leads to a loss of second‐order behavior. The greatest accelerations are seen with LiCl and dilute DNA. Volume exclusion by dextran sul...... hiện toàn bộ
Excluded volume as a determinant of macromolecular structure and reactivity
Biopolymers - Tập 20 Số 10 - Trang 2093-2120 - 1981
Allen P. Minton
AbstractThe effect of excluded volume on the thermodynamic activity of globular macromolecules and macromolecular complexes in solution is studied in the hard‐particle approximation. Activity coefficients are calculated as a function of the fraction of total volume occupied by macromolecules using relations obtained from scaled particle and lattice models. Signific...... hiện toàn bộ
The influence of macromolecular crowding on thermodynamic activity: Solubility and dimerization constants for spherical and dumbbell‐shaped molecules in a hard‐sphere mixture
Biopolymers - Tập 30 Số 11-12 - Trang 1027-1037 - 1990
Otto G. Berg
AbstractMacromolecules in solution can have large effects on the properties of other solutes through nonideal excluded‐volume (crowding) interactions. Minton [(1983) Mol. Cell. Biochem. 55, 119–140] has calculated such effects by treating the macromolecules as a hard‐sphere fluid in a background of an inert structur...... hiện toàn bộ
Bioencapsulation of apomyoglobin in nanoporous organosilica sol–gel glasses: Influence of the siloxane network on the conformation and stability of a model protein
Biopolymers - Tập 91 Số 11 - Trang 895-906 - 2009
Bouzid Menaa, Yuya Miyagawa, Masahide Takahashi, Mar Herrero, V. Rives, Farid Menaa, Daryl K. Eggers
AbstractNanoporous sol–gel glasses were used as host materials for the encapsulation of apomyoglobin, a model protein employed to probe in a rational manner the important factors that influence the protein conformation and stability in silica‐based materials. The transparent glasses were prepared from tetramethoxysilane (TMOS) and modified with a series of mono‐, d...... hiện toàn bộ
Synthesis of some amino acids, sugars, and peptides in cold plasma abiotic synthesis of some high‐molecular‐weight proteid‐like structures (V)
Biopolymers - Tập 13 Số 5 - Trang 943-954 - 1974
Cristofor I. Simionescu, F. Dénès, D. Onac, G. Bloos
AbstractThe synthesis of some high‐molecular‐weight protenoid structures in radiofrequency cold plasma conditions are discussed. The fractionation results of the raw product and the spectrum of free and protenoid‐bound amino acids are given. The uv analysis of these compounds is presented.A protein‐forming mechanism that might have existed on the p...
Poly(L‐lysyl‐L‐alanyl‐α‐L‐glutamic acid). II. Conformational studies
Biopolymers - Tập 16 Số 7 - Trang 1527-1540 - 1977
H. Joseph Goren, Carl R. McMillin, A. G. Walton
AbstractThe solution characterization of poly(Lys‐Ala‐Glu) is described. This polytripeptide is zwitterionic at neutral pH and is shown to take on a conformation which is dictated by the state of ionization, molecular weight, temperature, and solvent. The polypeptide is almost entirely α‐helical at low pH and temperature for polymers of greater than 25,000 molecula...... hiện toàn bộ
Gaussian docking functions
Biopolymers - Tập 68 Số 1 - Trang 76-90 - 2003
Mark McGann, Harold R. Almond, Anthony Nicholls, Jennifer Grant, Frank J. Schoenen
AbstractA shape‐based Gaussian docking function is constructed which uses Gaussian functions to represent the shapes of individual atoms. A set of 20 trypsin ligand–protein complexes are drawn from the Protein Data Bank (PDB), the ligands are separated from the proteins, and then are docked back into the active sites using numerical optimization of this function. I...... hiện toàn bộ
Surface plasmon resonance spectroscopy: An emerging tool for the study of peptide–membrane interactions
Biopolymers - Tập 66 Số 1 - Trang 3-18 - 2002
Henriette Mozsolits, Marie‐Isabel Aguilar
AbstractThe interactions between peptides and membranes mediate a wide variety of biological processes, and characterization of the molecular details of these interactions is central to our understanding of cellular events such as protein trafficking, cellular signaling and ion‐channel formation. A wide variety of biophysical techniques have been combined with the ...... hiện toàn bộ
Conformational transitions of a dipeptide in water: Effects of imposed pathways using umbrella sampling techniques
Biopolymers - Tập 34 Số 3 - Trang 347-355 - 1994
Franca Fraternali, Wilfred F. van Gunsteren
AbstractThe free energy difference between two states of a molecular system separated by an energy barrier can generally be computed using the technique of umbrella sampling along a chosen reaction coordinate or pathway. The effect of a particular choice of pathway upon the obtained free energy difference is investigated by molecular dynamics simulation of a model ...... hiện toàn bộ
Các mô hình nguyên tử chiếm chỗ chính xác Dịch bởi AI
Biopolymers - Tập 3 Số 6 - Trang 665-679 - 1965
Walter L. Koltun
Tóm tắtNói ngắn gọn, các mô hình nguyên tử chiếm chỗ nhẹ, giá rẻ, chính xác và phù hợp đặc biệt cho việc xây dựng các đại phân tử có liên quan đến sinh học sẽ được cung cấp đến cộng đồng khoa học. Việc cung cấp các mô hình này, các Mô hình Corey‐Pauling‐Koltun, hay còn gọi là Mô hình C‐P‐K, sẽ kết thúc một chương trình kéo dài năm năm, trong đó có sự hợp tác của cá...... hiện toàn bộ
Tổng số: 160   
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 10