High-performance liquid chromatography of siderophores from fungiBiology of Metals - Tập 1 - Trang 9-17 - 1988
Silvia Konetschny-Rapp, Hans-Georg Huschka, Günther Winkelmanne, Günther Jung
A reversed-phase HPLC separation of iron(III) chelates of 16 representative fungal siderophores including ferrichromes, coprogens and triacetylfusarinine C was established in order to investigate siderophore production of fungi. For comparison purposes, the widely used bacterial siderophore ferrioxamine B was included. Culture filtrates of the fungiPenicillium resticulosum, Fusarium dimerum, Asper...... hiện toàn bộ
Sub-chronic iron overload triggers oxidative stress development in rat brain: implications for cell protectionBiology of Metals - Tập 29 - Trang 119-130 - 2015
Natacha E. Piloni, Juan C. Perazzo, Virginia Fernandez, Luis A. Videla, Susana Puntarulo
This work was aimed to test the hypothesis that sub-chronic administration of iron-dextran (Fe-dextran) (six doses of 50 mg Fe-dextran/kg) to rats triggers a transient oxidative stress in brain and mechanisms of cellular antioxidant defence. After 2 h of administration of the 6th dose, a significant increase of total Fe, the labile Fe pool (LIP), the lipid radical (LR•)/α-tocopherol (α-T) content...... hiện toàn bộ
Investigating the phytoavailability of metals in roots of Croton macrostachyus and Phytolacca dodecandra: induced rhizosphere processesBiology of Metals - Tập 36 - Trang 1347-1359 - 2023
Abebe Tsega Melese, Dessie Tibebe Ayele, Loai Aljerf, Dhia F. Al-Fekaiki, Mulugeta Legesse Akele
Medicinal plants are key component of complementary and alternative medicine, and constitute the first therapeutic strategy for majority of the global population, particularly in developing nations. Croton macrostachyus and Phytolacca dodecandra are among such plants, widely used to treat various diseases. The present study aimed at investigating the elemental composition of both plant root sample...... hiện toàn bộ
Mercury distribution and renal metallothionein induction after subchronic oral exposure in ratsBiology of Metals - Tập 9 - Trang 213-220 - 1996
Miguel Ángel Morcillo, Jesús Santamaria
The effects of long-term daily intake of low and high levels of mercury on its organ distribution and binding to renal metallothionein (MT) in male rats were studied. The animals were exposed to mercuric chloride labelled with203Hg via drinking water for 8 weeks (5, 50 and 500μ
m Hg). The greatest concentration of mercury was found in the kidneys. Similar levels of radioactivity in the buccal cavi...... hiện toàn bộ
Rhizoferrin — a novel siderophore from the fungusRhizopus microsporus var.rhizopodiformisBiology of Metals - Tập 4 - Trang 238-243 - 1991
Hartmut Drechsel, Jörg Metzger, Stefan Freund, Günther Jung, Johan R. Boelaert, Günther Winkelmann
From a strain ofRhizopus microsporus var.rhizopodiformis a novel siderophore, named rhizoferrin, was isolated by ion-exchange column chromatography, gel filtration and preparative HPLC. Hydrolysis with 6 M HCl and subsequent gas chromatography/mass spectrometry (GUMS) of the esterified/trifluoroacetylated derivatives indicated that citric acid and diaminobutane were the only constituents. From pos...... hiện toàn bộ
Uptake of copper from plasma proteins in cells where expression of CTR1 has been modulatedBiology of Metals - Tập 25 - Trang 697-709 - 2012
Theodros Z. Kidane, Ramin Farhad, Kyoung Jin Lee, Abraham Santos, Eric Russo, Maria C. Linder
Plasma proteins rather than amino acid chelates are the direct sources of copper for mammalian cells. In continuing studies on the mechanisms by which albumin and transcuprein deliver copper and the potential involvement of CTR1, rates of uptake from these proteins and Cu–histidine were compared in cells with/without CTR1 knockdown or knockout. siRNA knocked down expression of CTR1 mRNA 60–85% in ...... hiện toàn bộ
Dental amalgam and mercuryBiology of Metals - Tập 2 - Trang 25-30 - 1989
Ann Mari Aronsson, Birger Lind, Magnus Nylander, Monica Nordberg
Mercury concentration in intraoral air and urine of seven females with dental amalgam was measured before and after intake of one hard-boiled egg. A considerable decrease in mercury concentration in intraoral air was found. Twenty women with about equal dental amalgam status, with or without subjective symptoms related to dental amalgam, were also studied. Mercury concentrations in intraoral air a...... hiện toàn bộ