Biochemical Genetics
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Molecular and tissue-specific heterogeneity in HPRT deficiency
Biochemical Genetics - Tập 16 - Trang 1187-1202 - 1978
In several patients with different degrees of HPRT deficiencies, residual activities have been determined in both lysed and intact erythrocytes. No close correlation could be found between the degree of HPRT deficiency and the severity of the clinical expression. Unless HPRT activity in both intact and lysed erythrocytes was below detection level, the residual activity in intact red blood cells wa...... hiện toàn bộ
Molecular structure of a naturally occurring alcoholdehydrogenase null activity allele inDrosophilamelanogaster
Biochemical Genetics - Tập 28 - Trang 443-443 - 1990
EGR1/2 Inhibits Papillary Thyroid Carcinoma Cell Growth by Suppressing the Expression of PTEN and BAX
Biochemical Genetics - - 2021
Synchronous allelic expression at the glucosephosphate isomerase A and B loci in interspecific sunfish hybrids
Biochemical Genetics - Tập 14 - Trang 723-737 - 1976
Allelic isozymes of glucosephosphate isomerase at the Gpi-A and -B loci were separated by starch gel electrophoresis in the warmouth (Lepomis gulosus) and green sunfish (L. cyanellus). The specific tissue distributions and developmental expressions of the GPI-A2, -AB, and -B2 isozymes were not different between these two species. The synchrony of allelic expression in normal intraspecific sunfish ...... hiện toàn bộ
Opioid Exposure is Associated with Aberrant DNA Methylation of OPRM1 Promoter Region in a Chinese Han Population
Biochemical Genetics - Tập 56 - Trang 451-458 - 2018
The μ-opioid receptor (OPRM1) plays an important role in opiate addiction. The OPRM1 gene promoter showed hypermethylation in lymphocytes of opiate addicts as well as opioid medications users, while the methylation status displayed ethnic diversity. The purpose of the study was to investigate the methylation pattern of OPRM1 promoter in the Han Chinese population. We analyzed 22 CpG sites located ...... hiện toàn bộ
The structure of two distinct pancreatic amylase genes in mouse strain YBR
Biochemical Genetics - Tập 23 Số 7-8 - Trang 511-524 - 1985
The suppressor of forked mutation in Drosophila melanogaster: Interactions with the lozenge gene
Biochemical Genetics - - 1976
Circ-NUP98 Promotes Lung Adenocarcinoma Development Through Regulating CBX1 by miR-188-3p
Biochemical Genetics - - Trang 1-19 - 2023
Lung cancer has a high morbidity and mortality among malignant tumors, and lung adenocarcinoma (LUAD) is the main type of lung cancer. In recent years, circular RNAs (circRNAs) have been confirmed to play an important role in the generation and development of human cancer. However, the specific role and mechanism of circ-NUP98 in LUAD are still unclear and need to be further investigated. Circ-NUP...... hiện toàn bộ
Two MicroRNAs, miR-34a and miR-125a, Are Implicated in Bicuspid Aortopathy by Modulating Metalloproteinase 2
Biochemical Genetics - Tập 60 - Trang 286-302 - 2021
It has been recognized that wall shear stress plays an important role in the development of Bicuspid Aortopathy (BA), but the intrinsic mechanism is not well elucidated. This study aims to explore the underlying relationship between hemodynamical forces and pathological phenomenon. Total RNA was prepared from aortic wall tissues collected from 20 BA patients. RNA sequencing, bioinformatic analysis...... hiện toàn bộ
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