Carbamazepine reduces memory induced activation of mesial temporal lobe structures: a pharmacological fMRI-studyBMC Neurology - Tập 1 - Trang 1-6 - 2001
Hennric Jokeit, Michael Okujava, Friedrich G Woermann
It is not known whether carbamazepine (CBZ; a drug widely used in neurology and psychiatry) influences the blood oxygenation level dependent (BOLD) contrast changes induced by neuronal activation and measured by functional MRI (fMRI). We aimed to investigate the influence of CBZ on memory induced activation of the mesial temporal lobes in patients with symptomatic temporal lobe epilepsy (TLE). Twe...... hiện toàn bộ
Intrafamilial phenotypic heterogeneity in a Taiwanese family with a MAPT p.R5H mutation: a case report and literature reviewBMC Neurology - Tập 17 - Trang 1-7 - 2017
Hui-Chi Lin, Chin-Hsien Lin, Pei-Lung Chen, Shih-Jung Cheng, Pei-Hao Chen
Frontotemporal degeneration (FTD) is a clinically and genetically heterogeneous neurodegenerative disorder characterized by deficits in executive function that frequently overlaps with parkinsonism and motor neuron disorders. Several genes have been identified to cause autosomal dominant forms of FTD, including the gene coding for the protein associated with microtubule tau (MAPT). While most repo...... hiện toàn bộ
Protocol of a randomized open label multicentre trial comparing continuous intrajejunal levodopa infusion with deep brain stimulation in Parkinson’s disease - the INfusion VErsus STimulation (INVEST) studyBMC Neurology - Tập 20 - Trang 1-9 - 2020
D. van Poppelen, V. Sisodia, R. J. de Haan, M. G. W. Dijkgraaf, P. R. Schuurman, G. J. Geurtsen, A. E. M. Berk, R. M. A. de Bie, J. M. Dijk
Both Deep Brain Stimulation (DBS) and Continuous intrajejunal Levodopa Infusion (CLI) are effective therapies for the treatment of Parkinson’s disease (PD). To our knowledge, no direct head-to-head comparison of DBS and CLI has been performed, whilst the costs probably differ significantly. In the INfusion VErsus STimulation (INVEST) study, costs and effectiveness of DBS and CLI are compared in a ...... hiện toàn bộ
Impact of neurofibromatosis type 1 with plexiform neurofibromas on the health-related quality of life and work productivity of adult patients and caregivers in the UK: a cross-sectional surveyBMC Neurology -
Hyun Kyoo Yoo, A Porteous, Alvin Wei Tian Ng, Keval Haria, A Griffiths, Andrew Lloyd, Xiaoqin Yang, Gbenga Kazeem, Volkan Barut
Abstract
Background
Plexiform neurofibromas (PN) are complex, benign nerve-sheath tumours that occur in 30–50% of patients with neurofibromatosis type 1 (NF1), a rare, genetic disorder. PN are associated with substantial, heterogeneous morbidities that impact health-related quality of life (HRQoL), ...... hiện toàn bộ
Performance on the Frontal Assessment Battery is sensitive to frontal lobe damage in stroke patientsBMC Neurology - Tập 13 - Trang 1-10 - 2013
Bruno Kopp, Nina Rösser, Sandra Tabeling, Hans Jörg Stürenburg, Bianca de Haan, Hans-Otto Karnath, Karl Wessel
The Frontal Assessment Battery (FAB) is a brief battery of six neuropsychological tasks designed to assess frontal lobe function at bedside [Neurology 55:1621-1626, 2000]. The six FAB tasks explore cognitive and behavioral domains that are thought to be under the control of the frontal lobes, most notably conceptualization and abstract reasoning, lexical verbal fluency and mental flexibility, moto...... hiện toàn bộ
The efficacy of transdiagnostic cognitive behavioral therapy on migraine headache: a pilot, feasibility studyBMC Neurology - Tập 22 - Trang 1-13 - 2022
Forouzandeh Soleimanian-Boroujeni, Negin Badihian, Shervin Badihian, Vahid Shaygannejad, Yousef Gorji
Psychological interventions are shown to be effective in migraine, but not utilized routinely yet. We aimed to evaluate the efficacy of transdiagnostic cognitive behavioral therapy (TCBT) on people with migraine (PwM). This study was conducted on 40 PwM aged 20–50 years. We randomly assigned participants to two groups of intervention, receiving 10 sessions of TCBT, and control, attending one sessi...... hiện toàn bộ