Carbamazepine reduces memory induced activation of mesial temporal lobe structures: a pharmacological fMRI-studyBMC Neurology - Tập 1 - Trang 1-6 - 2001
Hennric Jokeit, Michael Okujava, Friedrich G Woermann
It is not known whether carbamazepine (CBZ; a drug widely used in neurology and psychiatry) influences the blood oxygenation level dependent (BOLD) contrast changes induced by neuronal activation and measured by functional MRI (fMRI). We aimed to investigate the influence of CBZ on memory induced activation of the mesial temporal lobes in patients with symptomatic temporal lobe epilepsy (TLE). Twe...... hiện toàn bộ
Intrafamilial phenotypic heterogeneity in a Taiwanese family with a MAPT p.R5H mutation: a case report and literature reviewBMC Neurology - Tập 17 - Trang 1-7 - 2017
Hui-Chi Lin, Chin-Hsien Lin, Pei-Lung Chen, Shih-Jung Cheng, Pei-Hao Chen
Frontotemporal degeneration (FTD) is a clinically and genetically heterogeneous neurodegenerative disorder characterized by deficits in executive function that frequently overlaps with parkinsonism and motor neuron disorders. Several genes have been identified to cause autosomal dominant forms of FTD, including the gene coding for the protein associated with microtubule tau (MAPT). While most repo...... hiện toàn bộ
Protocol of a randomized open label multicentre trial comparing continuous intrajejunal levodopa infusion with deep brain stimulation in Parkinson’s disease - the INfusion VErsus STimulation (INVEST) studyBMC Neurology - Tập 20 - Trang 1-9 - 2020
D. van Poppelen, V. Sisodia, R. J. de Haan, M. G. W. Dijkgraaf, P. R. Schuurman, G. J. Geurtsen, A. E. M. Berk, R. M. A. de Bie, J. M. Dijk
Both Deep Brain Stimulation (DBS) and Continuous intrajejunal Levodopa Infusion (CLI) are effective therapies for the treatment of Parkinson’s disease (PD). To our knowledge, no direct head-to-head comparison of DBS and CLI has been performed, whilst the costs probably differ significantly. In the INfusion VErsus STimulation (INVEST) study, costs and effectiveness of DBS and CLI are compared in a ...... hiện toàn bộ
Association between serum triglycerides and stroke type, severity, and prognosis. Analysis in 6558 patientsBMC Neurology - - 2024
Naveed Akhtar, Rajvir Singh, Saadat Kamran, Sujatha Joseph, Deborah Morgan, Ryan Ty Uy, Sarah Treit, Ashfaq Shuaib
Hypertriglyceridemia (HT) may increase the risk of stroke. Limited studies have shown that stroke severity and infarction size are smaller in patients with HT. We explored the relationship between triglyceride levels and stroke risk factors, severity and outcome in a large prospective database. Prospective Cross-sectional study. We retrospectively interrogated the Qatar Stroke Database in all pati...... hiện toàn bộ
A survey of subjective constipation in Parkinson’s disease patients in shanghai and literature reviewBMC Neurology - Tập 18 - Trang 1-9 - 2018
Jing Gan, Ying Wan, Junjie Shi, Mingzhu Zhou, Zhiyin Lou, Zhenguo Liu
Constipation is one of the most frequent non-motor symptoms (NMS) in Parkinson’s disease (PD) and the prevalence of constipation in PD patients varies among different studies. We designed this study to survey the prevalence and clinical characteristics of subjective constipation and the appearance chronology between the emergence of constipation and onset of motor symptoms in PD patients from Shan...... hiện toàn bộ
Persistence with treatment for Wilson disease: a retrospective studyBMC Neurology - Tập 19 - Trang 1-6 - 2019
Wojciech Masełbas, Anna Członkowska, Tomasz Litwin, Maciej Niewada
Wilson disease (WD) is genetically induced failure of copper metabolism which can be successfully treated with pharmacological agents. The prognosis for survival in most WD patients is favorable if diagnosis and anti-copper treatment are provided early. Many observations imply that persistence with drug treatment is generally low in patients with chronic diseases, which impact the treatment effect...... hiện toàn bộ