BMC Microbiology

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The role of MglA for adaptation to oxidative stress of Francisella tularensis LVS
BMC Microbiology - Tập 12 - Trang 1-11 - 2012
Marie Honn, Helena Lindgren, Anders Sjöstedt
The Francisella tularensis protein MglA performs complex regulatory functions since it influences the expression of more than 100 genes and proteins in F. tularensis. Besides regulating the igl operon, it has been suggested that it also regulates several factors such as SspA, Hfq, CspC, and UspA, all important to stress adaptation. Therefore, it can be hypothesized that MglA plays an important rol...... hiện toàn bộ
The temporal and spatial endophytic fungal community of Huperzia serrata: diversity and relevance to huperzine A production by the host
BMC Microbiology - Tập 22 - Trang 1-13 - 2022
Zhuhui Shen, Xubing Liu, Jia Yang, Yanli Wang, Kai Yao, Qingmiao Huo, Yanping Fu, Yahui Wei, Bin Guo
Plants maintain the steady-state balance of the mutually beneficial symbiosis relationship with their endophytic fungi through secondary metabolites. Meanwhile endophytic fungi can serve as biological inducers to promote the biosynthesis and accumulation of valuable secondary metabolites in host plants through a variety of ways. The composition and structure of endophytic fungal community are affe...... hiện toàn bộ
Regulation of bacteria population behaviors by AI-2 “consumer cells” and “supplier cells”
BMC Microbiology - Tập 17 - Trang 1-9 - 2017
Yufen Quan, Fankang Meng, Xinyu Ma, Xinhao Song, Xiao Liu, Weixia Gao, Yulei Dang, Yao Meng, Mingfeng Cao, Cunjiang Song
Autoinducer-2 (AI-2) is a universal signal molecule and enables an individual bacteria to communicate with each other and ultimately control behaviors of the population. Harnessing the character of AI-2, two kinds of AI-2 “controller cells” (“consumer cells” and “supplier cells”) were designed to “reprogram” the behaviors of entire population. For the consumer cells, genes associated with the upta...... hiện toàn bộ
A large scale comparative genomic analysis reveals insertion sites for newly acquired genomic islands in bacterial genomes
BMC Microbiology - Tập 11 - Trang 1-7 - 2011
Pengcheng Du, Yinxue Yang, Haiying Wang, Di Liu, George F Gao, Chen Chen
Bacterial virulence enhancement and drug resistance are major threats to public health worldwide. Interestingly, newly acquired genomic islands (GIs) from horizontal transfer between different bacteria strains were found in Vibrio cholerae, Streptococcus suis, and Mycobacterium tuberculosis, which caused outbreak of epidemic diseases in recently years. Using a large-scale comparative genomic analy...... hiện toàn bộ
Ecology impacts the decrease of Spirochaetes and Prevotella in the fecal gut microbiota of urban humans
BMC Microbiology -
Louise B. Thingholm, Corinna Bang, Malte C. Rühlemann, Annika Starke, Florian Sicks, Verena Kaspari, Anabell Jandowsky, Kai Frölich, Gabriele Ismer, Andreas Bernhard, Claudia Bombis, Barbara Struve, Philipp Rausch, André Franke
AbstractCompared to the huge microbial diversity in most mammals, human gut microbiomes have lost diversity while becoming specialized for animal-based diets – especially compared to chimps, their genetically closest ancestors. The lowered microbial diversity within the gut of westernized populations has also been associated with different kinds of chronic inflamma...... hiện toàn bộ
Oral microbiome homogeneity across diverse human groups from southern Africa: first results from southwestern Angola and Zimbabwe
BMC Microbiology - Tập 23 Số 1
Vı́tor Araújo, Anne-Maria Fehn, Admire Phiri, Jeffrey Wills, Jorge Rocha, Magdalena Gayà-Vidal
Abstract Background While the human oral microbiome is known to play an important role in systemic health, its average composition and diversity patterns are still poorly understood. To gain better insights into the general composition of the microbiome on a global scale, the characterization of mic...... hiện toàn bộ
Broad-range potential of Asphodelus microcarpus leaves extract for drug development
BMC Microbiology - Tập 17 - Trang 1-9 - 2017
Amalia Di Petrillo, Antonella Fais, Francesca Pintus, Celestino Santos-Buelga, Ana M. González-Paramás, Vincenzo Piras, Germano Orrù, Antonello Mameli, Enzo Tramontano, Aldo Frau
Many plants have been used in traditional medicine for their antibacterial, antifungal, antiprotozoal, antiviral, antidiarrhoeal, analgesic, antimalarial, antioxidant, anti-inflammatory and anticancer activities. In order to find novel antimicrobial and antiviral agents, the aim of the present study was the evaluation of the antibacterial and antibiofilm susceptibility of Asphodelus microcarpus le...... hiện toàn bộ
Flavaspidic acid BB combined with mupirocin improves its anti-bacterial and anti-biofilm activities against Staphylococcus epidermidis
BMC Microbiology - Tập 22 - Trang 1-13 - 2022
Zhiling Cai, Zitong Mo, Shiqian Zheng, Shihua Lan, Shengjun Xie, Jinghui Lu, Chunping Tang, Zhibin Shen
The increase in drug-resistant opportunistic pathogenic bacteria, especially of antibiotic-resistant Staphylococcus epidermidis (S. epidermidis), has led to difficulties in the treatment of skin and soft tissue infections (SSTI). The major reason for bacterial resistance is the formation of bacterial biofilm. Here, we report a promising combination therapy of flavaspidic acid BB (BB) and mupirocin...... hiện toàn bộ
Morphology and molecular phylogeny of a marine interstitial tetraflagellate with putative endosymbionts: Auranticordis quadriverberis n. gen. et sp. (Cercozoa)
BMC Microbiology - Tập 8 Số 1 - Trang 1-16 - 2008
Chantangsi, Chitchai, Esson, Heather J, Leander, Brian S
Comparative morphological studies and environmental sequencing surveys indicate that marine benthic environments contain a diverse assortment of microorganisms that are just beginning to be explored and characterized. The most conspicuous predatory flagellates in these habitats range from about 20–150 μm in size and fall into three major groups of eukaryotes that are very distantly related to one ...... hiện toàn bộ
PCR-based rapid genotyping of Stenotrophomonas maltophiliaisolates
BMC Microbiology - Tập 8 - Trang 1-9 - 2008
Emanuela Roscetto, Francesco Rocco, M Stella Carlomagno, Mariassunta Casalino, Bianca Colonna, Raffaele Zarrilli, Pier Paolo Di Nocera
All bacterial genomes contain repetitive sequences which are members of specific DNA families. Such repeats may occur as single units, or found clustered in multiple copies in a head-to-tail configuration at specific loci. The number of clustered units per locus is a strain-defining parameter. Assessing the length variability of clusters of repeats is a versatile typing methodology known as multil...... hiện toàn bộ
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