BMC Genetics
Công bố khoa học tiêu biểu
* Dữ liệu chỉ mang tính chất tham khảo
Sắp xếp:
Comparison of weighting approaches for genetic risk scores in gene-environment interaction studies
BMC Genetics - Tập 18 - Trang 1-12 - 2017
Weighted genetic risk scores (GRS), defined as weighted sums of risk alleles of
single nucleotide polymorphisms (SNPs), are statistically powerful for detection
gene-environment (GxE) interactions. To assign weights, the gold standard is to
use external weights from an independent study. However, appropriate external
weights are not always available. In such situations and in the presence of
predo...
Power and sample size calculations in the presence of phenotype errors for case/control genetic association studies
BMC Genetics - Tập 6 - Trang 1-12 - 2005
Phenotype error causes reduction in power to detect genetic association. We
present a quantification of phenotype error, also known as diagnostic error, on
power and sample size calculations for case-control genetic association studies
between a marker locus and a disease phenotype. We consider the classic Pearson
chi-square test for independence as our test of genetic association. To
determine as...
Improving the efficiency of feed utilization in poultry by selection. 1. Genetic parameters of anatomy of the gastro-intestinal tract and digestive efficiency
BMC Genetics - Tập 12 - Trang 1-9 - 2011
Feed costs represent about 70% of the costs of raising broilers. The main way to
decrease these costs is to improve feed efficiency by modification of diet
formulation, but one other possibility would be to use genetic selection.
Understanding the genetic architecture of the gastro-intestinal tract (GIT) and
the impact of the selection criterion on the GIT would be of particular
interest. We there...
Recombination of the porcine X chromosome: a high density linkage map
BMC Genetics - Tập 15 - Trang 1-6 - 2014
Linkage maps are essential tools for the study of several topics in genome
biology. High density linkage maps for the porcine autosomes have been
constructed exploiting the high density data provided by the PorcineSNP60
BeadChip. However, a high density SSCX linkage map has not been reported up to
date. The aim of the current study was to build an accurate linkage map of SSCX
to provide precise es...
Genetic diversity among eight Dendrolimus species in Eurasia (Lepidoptera: Lasiocampidae) inferred from mitochondrial COI and COII, and nuclear ITS2 markers
BMC Genetics - Tập 17 Số S3 - 2016
Genome-wide deficiency screen for the genomic regions responsible for heat resistance in Drosophila melanogaster
BMC Genetics - - 2011
Genotyping human ancient mtDNA control and coding region polymorphisms with a multiplexed Single-Base-Extension assay: the singular maternal history of the Tyrolean Iceman
BMC Genetics - Tập 10 - Trang 1-14 - 2009
Progress in the field of human ancient DNA studies has been severely restricted
due to the myriad sources of potential contamination, and because of the
pronounced difficulty in identifying authentic results. Improving the robustness
of human aDNA results is a necessary pre-requisite to vigorously testing
hypotheses about human evolution in Europe, including possible admixture with
Neanderthals. T...
Comparison of missing data approaches in linkage analysis
BMC Genetics - Tập 4 - Trang 1-4 - 2003
Observational cohort studies have been little used in linkage analyses due to
their general lack of large, disease-specific pedigrees. Nevertheless, the
longitudinal nature of such studies makes them potentially valuable for
assessing the linkage between genotypes and temporal trends in phenotypes. The
repeated phenotype measures in cohort studies (i.e., across time), however, can
have extensive m...
Candidate genes in quantitative trait loci associated with absolute and relative kidney weight in rats with Inherited Stress Induced Arterial Hypertension
BMC Genetics - Tập 16 - Trang 1-13 - 2015
The kidney mass is significantly increased in hypertensive ISIAH rats with
Inherited Stress Induced Arterial Hypertension as compared with normotensive WAG
rats. The QTL/microarray approach was carried out to determine the positional
candidate genes in the QTL for absolute and relative kidney weight. Several
known and predicted genes differentially expressed in ISIAH and WAG kidney were
mapped to ...
Estimation of genetic parameters and detection of quantitative trait loci for minerals in Danish Holstein and Danish Jersey milk
BMC Genetics - Tập 16 - Trang 1-8 - 2015
Bovine milk provides important minerals, essential for human nutrition and dairy
product quality. For changing the mineral composition of the milk to improve
dietary needs in human nutrition and technological properties of milk, a
thorough understanding of the genetics underlying milk mineral contents is
important. Therefore the aim of this study was to 1) estimate the genetic
parameters for indiv...
Tổng số: 1,432
- 1
- 2
- 3
- 4
- 5
- 6
- 10