BMC Endocrine Disorders

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Increased circulating FGF21 level predicts the burden of metabolic demands and risk of vascular diseases in adults with type 2 diabetes
BMC Endocrine Disorders - Tập 23 Số 1
Zhen Liu, Yue Peng, Supeng Li, Yu‐Sheng Lin, Yunfeng Huang, Wenting Chen, Chunhua Bao, Zengxian Zhou, Lin Zeng, Liangmiao Chen
Abstract Objectives Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by chronic hyperglycemia and metabolic stress, involved in the stepwise development of cardiovascular complications. Fibroblast growth factor 21 (FGF21) is a novel hepatokine involved in regulating gluc...... hiện toàn bộ
Diagnosis and treatment of primary central nervous system lymphoma with the primary lesion in the hypothalamus: a case report
BMC Endocrine Disorders - Tập 21 - Trang 1-6 - 2021
Ken Takao, Ayaka Tani, Tetsuya Suwa, Yayoi Kuwabara-Ohmura, Kenta Nonomura, Yanyan Liu, Takehiro Kato, Masami Mizuno, Takuo Hirota, Mayumi Enya, Katsumi Iizuka, Yukio Horikawa, Chiemi Saigo, Yusuke Kito, Tatsuhiko Miyazaki, Naoyuki Ohe, Toru Iwama, Daisuke Yabe
Primary central nervous system lymphoma is a rare extra-nodal lymphoma of the central nervous system. Primary central nervous system lymphoma lesions usually appear in the vicinity of the ventricle, and there are few reports of primary central nervous system lymphoma with hypothalamic-pituitary lesions. We treated a 56-year-old male with primary central nervous system lymphoma with the primary les...... hiện toàn bộ
Brown tumor due to primary hyperparathyroidism in a familial case: a case report
BMC Endocrine Disorders - Tập 23 - Trang 1-8 - 2023
Zongping Diao, Jianquan Zhang, Jiaqi Zhao, Weihu Sun, Zhengguo Pu
Primary hyperparathyroidism (PHPT) is an uncommon disorder characterised by hypercalcemia with an increased parathyroid hormone level. We reported a PHPT familial case with two subjects, a father and a daughter, and both of them had suffered from the brown tumor. The proband, a 43-year-old patient, developed parathyroid adenomas at the age of 15; a histologically confirmed right parathyroid adenom...... hiện toàn bộ
Magnitude of erectile dysfunction and associated factors among adult diabetic men on follow-up at Goba and Robe hospitals, Bale Zone, South East Ethiopia: hospital-based cross-sectional study
BMC Endocrine Disorders - Tập 23 - Trang 1-10 - 2023
Telila Mesfin, Yohannes Tekalegn, Ahmednur Adem, Kenbon Seyoum, Girma Geta, Biniyam Sahiledengle, Eshetu Mesfin, Demisu Zenbaba, Fikreab Desta, Girma Beressa, Mesfin Tsegaye, Neway Ejigu, Degefa Gomora
Erectile dysfunction is defined as the inability to achieve and/or maintain an erection of sufficient rigidity and duration to permit satisfactory sexual performance. The purpose of this study is to assess the prevalence of erectile dysfunction and associated factors among adult diabetic men on follow-up at Goba and Robe hospitals, Bale Zone, South East Ethiopia,2022. Hospital-based cross-sectiona...... hiện toàn bộ
Frequency and determinants of thyroid autoimmunity in Ghanaian type 2 diabetes patients: a case-control study
BMC Endocrine Disorders - - 2017
Osei Sarfo-Kantanka, Fred Stephen Sarfo, Eunice Oparebea Ansah, Ernest Yorke, Josephine Akpalu, Bernard C. Nkum, Benjamin Eghan
The link between type 1 diabetes and thyroid autoimmunity is well described. The same cannot be said for type 2 diabetes where results have been mixed so far. We investigated the prevalence and determinants of thyroid autoimmunity among Ghanaian type 2 diabetes patients. This was a case-control study involving 302 type 2 diabetes patients and 310 non - diabetic controls aged 40–80 years. Anthropom...... hiện toàn bộ
Characteristics and outcomes of patients with type 2 diabetes mellitus treated with canagliflozin: a real-world analysis
BMC Endocrine Disorders - Tập 15 - Trang 1-10 - 2015
Erin K. Buysman, Wing Chow, Henry J. Henk, Marcia F. T. Rupnow
Canagliflozin, an oral agent that inhibits sodium glucose co-transporter 2, improves glycemic control, body weight, and blood pressure and is generally well tolerated in patients with type 2 diabetes mellitus (T2DM). This study extends the scope of previous analyses by evaluating outcomes associated with the use of canagliflozin over a 6-month period in a real-world setting. This retrospective coh...... hiện toàn bộ
Oxytocin and cardioprotection in diabetes and obesity
BMC Endocrine Disorders - Tập 16 - Trang 1-9 - 2016
Marek Jankowski, Tom L. Broderick, Jolanta Gutkowska
Oxytocin (OT) emerges as a drug for the treatment of diabetes and obesity. The entire OT system is synthesized in the rat and human heart. The direct myocardial infusion with OT into an ischemic or failing heart has the potential to elicit a variety of cardioprotective effects. OT treatment attenuates cardiomyocyte (CMs) death induced by ischemia-reperfusion by activating pro-survival pathways wit...... hiện toàn bộ
Association of apolipoproteins A1 and B with type 2 diabetes and fasting blood glucose: a cross-sectional study
BMC Endocrine Disorders - Tập 21 - Trang 1-11 - 2021
Liang Gao, Yaju Zhang, Xingmin Wang, Hongli Dong
Apolipoprotein (Apo) may be associated with type 2 diabetes (T2D), however, little is known whether or not serum apolipoproteins are correlated with fasting blood glucose (FBG) and the prevalence of T2D in Chinese populations. In this study, we examined the association of serum ApoA1, ApoB, and the ratio of ApoB/ApoA1 (ApoB/A1 ratio) with T2D and FBG level, and compared apolipoprotein indicators i...... hiện toàn bộ
Alterations of SOCS1 and SOCS3 transcript levels, but not promoter methylation levels in subcutaneous adipose tissues in obese women
BMC Endocrine Disorders - Tập 23 - Trang 1-12 - 2023
Solaleh Emamgholipour, Fataneh Esmaeili, Maryam Shabani, Seyedeh Zahra Hasanpour, Mahsa Pilehvari, Hossein Zabihi-Mahmoudabadi, Meysam Motevasseli, Mehrnoosh Shanaki
Animal model studies suggest that change in the members of the suppressor of the cytokine signaling (SOCS) family (mainly SOCS1 and SOCS3) is linked to the pathogenesis of obesity-related metabolic disorders. Moreover, epigenetic modification is involved in the transcriptional regulation of the SOCS gene family. Here, we aimed to evaluate the mRNA expression as well as gene promoter methylation of...... hiện toàn bộ
Diabetic ketoacidosis and hyperglycemic hyperosmolar syndrome after renal transplantation in the United States
BMC Endocrine Disorders - - 2003
Kevin C. Abbott, Victor Bernet, Lawrence Y. Agodoa, Christina M. Yuan
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