Spiropyran as a potential molecular diagnostic tool for double-stranded RNA detectionBMC Biomedical Engineering - Tập 1 - Trang 1-13 - 2019
Ahsan Ausaf Ali, Minjeong Kang, Raisa Kharbash, Yoosik Kim
Long double-stranded RNAs (dsRNAs) are duplex RNAs that can induce immune response when present in mammalian cells. These RNAs are historically associated with viral replication, but recent evidence suggests that human cells naturally encode endogenous dsRNAs that can regulate antiviral machineries in cellular contexts beyond immune response. In this study, we use photochromic organic compound spi...... hiện toàn bộ
A novel suprachoroidal microinvasive glaucoma implant: in vivo biocompatibility and biointegrationBMC Biomedical Engineering - - 2020
Ian Grierson, Don S. Minckler, Marian K. Rippy, Andrew J. Marshall, Nathalie Collignon, Jessica Bianco, Bruno Detry, Murray Johnstone
Abstract
Background
A major challenge for any glaucoma implant is their ability to provide long-term intraocular pressure lowering efficacy. The formation of a low-permeability fibrous capsule around the device often leads to obstructed drainage channels, which may impair the drainage function of de...... hiện toàn bộ
Electric field stimulation for tissue engineering applicationsBMC Biomedical Engineering - Tập 3 - Trang 1-9 - 2021
Christina N. M. Ryan, Meletios N. Doulgkeroglou, Dimitrios I. Zeugolis
Electric fields are involved in numerous physiological processes, including directional embryonic development and wound healing following injury. To study these processes in vitro and/or to harness electric field stimulation as a biophysical environmental cue for organised tissue engineering strategies various electric field stimulation systems have been developed. These systems are overall simila...... hiện toàn bộ
A portable assist-as-need upper-extremity hybrid exoskeleton for FES-induced muscle fatigue reduction in stroke rehabilitationBMC Biomedical Engineering - Tập 1 - Trang 1-17 - 2019
Ashley Stewart, Christopher Pretty, Xiaoqi Chen
Hybrid exoskeletons are a recent development which combine Functional Electrical Stimulation with actuators to improve both the mental and physical rehabilitation of stroke patients. Hybrid exoskeletons have been shown capable of reducing the weight of the actuator and improving movement precision compared to Functional Electrical Stimulation alone. However little attention has been given towards ...... hiện toàn bộ
An open-access plug-in program for 3D modelling distinct material properties of cortical and trabecular boneBMC Biomedical Engineering - Tập 4 - Trang 1-6 - 2022
Gregory R. Roytman, Matan Cutler, Kenneth Milligan, Steven M. Tommasini, Daniel H. Wiznia
Finite element modelling the material behavior of bone in-silico is a powerful tool to predict the best suited surgical treatment for individual patients. We demonstrate the development and use of a pre-processing plug-in program with a 3D modelling image processing software suite (Synopsys Simpleware, ScanIP) to assist with identifying, isolating, and defining cortical and trabecular bone materia...... hiện toàn bộ
An automatic nuclei segmentation method based on deep convolutional neural networks for histopathology imagesBMC Biomedical Engineering - Tập 1 - Trang 1-12 - 2019
Hwejin Jung, Bilal Lodhi, Jaewoo Kang
Since nuclei segmentation in histopathology images can provide key information for identifying the presence or stage of a disease, the images need to be assessed carefully. However, color variation in histopathology images, and various structures of nuclei are two major obstacles in accurately segmenting and analyzing histopathology images. Several machine learning methods heavily rely on hand-cra...... hiện toàn bộ
Approaches in cooling of resistive coil-based low-field Magnetic Resonance Imaging (MRI) systems for application in low resource settingsBMC Biomedical Engineering - Tập 3 - Trang 1-11 - 2021
Faith Natukunda, Theodora M. Twongyirwe, Steven J. Schiff, Johnes Obungoloch
Magnetic Resonance Imaging (MRI), a non-invasive method for the diagnosis of diverse health conditions has experienced growing popularity over other imaging modalities like ultrasound and Computer Tomography. Initially, proof-of-concept and earlier MRI systems were based on resistive and permanent magnet technology. However, superconducting magnets have long held monopoly of the market for MRI sys...... hiện toàn bộ