Spiropyran as a potential molecular diagnostic tool for double-stranded RNA detectionBMC Biomedical Engineering - Tập 1 - Trang 1-13 - 2019
Ahsan Ausaf Ali, Minjeong Kang, Raisa Kharbash, Yoosik Kim
Long double-stranded RNAs (dsRNAs) are duplex RNAs that can induce immune
response when present in mammalian cells. These RNAs are historically associated
with viral replication, but recent evidence suggests that human cells naturally
encode endogenous dsRNAs that can regulate antiviral machineries in cellular
contexts beyond immune response. In this study, we use photochromic organic
compound spi... hiện toàn bộ
A novel suprachoroidal microinvasive glaucoma implant: in vivo biocompatibility and biointegrationBMC Biomedical Engineering - - 2020
Ian Grierson, Don S. Minckler, Marian K. Rippy, Andrew J. Marshall, Nathalie Collignon, Jessica Bianco, Bruno Detry, Murray Johnstone
Abstract Background A major challenge for any glaucoma implant is their ability
to provide long-term intraocular pressure lowering efficacy. The formation of a
low-permeability fibrous capsule around the device often leads to obstructed
drainage channels, which may impair the drainage function of devices. These
foreign body-related limitations point to the need to develop biologically inert
biomat... hiện toàn bộ
Electric field stimulation for tissue engineering applicationsBMC Biomedical Engineering - Tập 3 - Trang 1-9 - 2021
Christina N. M. Ryan, Meletios N. Doulgkeroglou, Dimitrios I. Zeugolis
Electric fields are involved in numerous physiological processes, including
directional embryonic development and wound healing following injury. To study
these processes in vitro and/or to harness electric field stimulation as a
biophysical environmental cue for organised tissue engineering strategies
various electric field stimulation systems have been developed. These systems
are overall simila... hiện toàn bộ
A portable assist-as-need upper-extremity hybrid exoskeleton for FES-induced muscle fatigue reduction in stroke rehabilitationBMC Biomedical Engineering - Tập 1 - Trang 1-17 - 2019
Ashley Stewart, Christopher Pretty, Xiaoqi Chen
Hybrid exoskeletons are a recent development which combine Functional Electrical
Stimulation with actuators to improve both the mental and physical
rehabilitation of stroke patients. Hybrid exoskeletons have been shown capable
of reducing the weight of the actuator and improving movement precision compared
to Functional Electrical Stimulation alone. However little attention has been
given towards ... hiện toàn bộ
An open-access plug-in program for 3D modelling distinct material properties of cortical and trabecular boneBMC Biomedical Engineering - Tập 4 - Trang 1-6 - 2022
Gregory R. Roytman, Matan Cutler, Kenneth Milligan, Steven M. Tommasini, Daniel H. Wiznia
Finite element modelling the material behavior of bone in-silico is a powerful
tool to predict the best suited surgical treatment for individual patients. We
demonstrate the development and use of a pre-processing plug-in program with a
3D modelling image processing software suite (Synopsys Simpleware, ScanIP) to
assist with identifying, isolating, and defining cortical and trabecular bone
materia... hiện toàn bộ
An automatic nuclei segmentation method based on deep convolutional neural networks for histopathology imagesBMC Biomedical Engineering - Tập 1 - Trang 1-12 - 2019
Hwejin Jung, Bilal Lodhi, Jaewoo Kang
Since nuclei segmentation in histopathology images can provide key information
for identifying the presence or stage of a disease, the images need to be
assessed carefully. However, color variation in histopathology images, and
various structures of nuclei are two major obstacles in accurately segmenting
and analyzing histopathology images. Several machine learning methods heavily
rely on hand-cra... hiện toàn bộ