BMC Biomedical Engineering
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Spiropyran as a potential molecular diagnostic tool for double-stranded RNA detection
BMC Biomedical Engineering - Tập 1 - Trang 1-13 - 2019
Long double-stranded RNAs (dsRNAs) are duplex RNAs that can induce immune response when present in mammalian cells. These RNAs are historically associated with viral replication, but recent evidence suggests that human cells naturally encode endogenous dsRNAs that can regulate antiviral machineries in cellular contexts beyond immune response. In this study, we use photochromic organic compound spi......
A portable assist-as-need upper-extremity hybrid exoskeleton for FES-induced muscle fatigue reduction in stroke rehabilitation
BMC Biomedical Engineering - Tập 1 - Trang 1-17 - 2019
Hybrid exoskeletons are a recent development which combine Functional Electrical Stimulation with actuators to improve both the mental and physical rehabilitation of stroke patients. Hybrid exoskeletons have been shown capable of reducing the weight of the actuator and improving movement precision compared to Functional Electrical Stimulation alone. However little attention has been given towards ......
Skin substitutes are more potent than dermal or epidermal substitutes in stimulating endothelial cell sprouting
BMC Biomedical Engineering - Tập 1 - Trang 1-7 - 2019
Therapy resistant ulcers are wounds that remain open for a long time period and often arise from chronic venous disease, prolonged pressure or diabetes. For healing of chronic wounds, revitalization of the inert wound bed, which is achieved by angiogenic sprouting of new blood vessels is of great importance. An alternative treatment option to conventional therapies is the use of skin substitutes: ......
Mechanisms of action, chemical characteristics, and model systems of obesogensAbstract There is increasing evidence for the role of environmental endocrine disrupting contaminants, coined obesogens, in exacerbating the rising obesity epidemic. Obesogens can be found in everyday items ranging from pesticides to food packaging. Although research shows that obesogens can have effects on adipocyte size, phenotype, metabolic activity, and hormone ... ...
BMC Biomedical Engineering - Tập 2 Số 1 - 2020
3D Printed frames to enable reuse and improve the fit of N95 and KN95 respirators
BMC Biomedical Engineering - Tập 3 - Trang 1-14 - 2021
In response to supply shortages caused by the COVID-19 pandemic, N95 filtering facepiece respirators (FFRs or “masks”), which are typically single-use devices in healthcare settings, are routinely being used for prolonged periods and in some cases decontaminated under “reuse” and “extended use” policies. However, the reusability of N95 masks is limited by degradation of fit. Possible substitutes, ......
Exploring the role of transtibial prosthetic use in deep tissue injury development: a scoping review
BMC Biomedical Engineering - Tập 2 - Trang 1-17 - 2020
The soft tissue of the residual limb in transtibial prosthetic users encounters unique biomechanical challenges. Although not intended to tolerate high loads and deformation, it becomes a weight-bearing structure within the residuum-prosthesis-complex. Consequently, deep soft tissue layers may be damaged, resulting in Deep Tissue Injury (DTI). Whilst considerable effort has gone into DTI research ......
An upper body garment with integrated sensors for people with neurological disorders – early development and evaluation
BMC Biomedical Engineering - Tập 1 - Trang 1-13 - 2019
In neurology and rehabilitation the primary interest for using wearables is to supplement traditional patient assessment and monitoring in hospital settings with continuous data collection at home and in community settings. The aim of this project was to develop a novel wearable garment with integrated sensors designed for continuous monitoring of physiological and movement related variables to ev......
Correction to: Osteogenic potential of heterogeneous and CD271-enriched mesenchymal stromal cells cultured on apatite-wollastonite 3D scaffolds
BMC Biomedical Engineering - Tập 1 - Trang 1-6 - 2019
In the original publication of this article [1] the figures and captions were linked incorrectly. In this correction article the figures & captions are correctly published.
A carbon nanotubes based in situ multifunctional power assist system for restoring failed heart function
BMC Biomedical Engineering - Tập 3 - Trang 1-13 - 2021
End-stage heart failure is a major risk of mortality. The conductive super-aligned carbon nanotubes sheets (SA-CNTs) has been applied to restore the structure and function of injured myocardium through tissue engineering, and developed as efficient cardiac pacing electrodes. However, the interfacial interaction between SA-CNTs and the surface cells is unclear, and it remains challenge to restore t......
Fourteen days free-living evaluation of an open-source algorithm for counting steps in healthy adults with a large variation in physical activity levelAbstract Background The number of steps by an individual, has traditionally been assessed with a pedometer, but increasingly with an accelerometer. The ActiLife software (AL) is the most common way to process accelerometer data to steps, but it is not open source which could aid understanding of measurement errors. The aim of this s...
BMC Biomedical Engineering - Tập 5 Số 1
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