Archiv für pathologische Anatomie und Physiologie und für klinische Medicin
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Ueber Mycosis fungoides (Granuloma fungoides)
Archiv für pathologische Anatomie und Physiologie und für klinische Medicin - Tập 116 - Trang 301-309 - 1889
Book Review—Practical Hepatic Pathology: A Diagnostic Approach, 2nd Edition
Archiv für pathologische Anatomie und Physiologie und für klinische Medicin - Tập 471 - Trang 819-820 - 2017
Breast tissue imaging atlas using ultra-fast confocal microscopy to identify cancer lesions
Archiv für pathologische Anatomie und Physiologie und für klinische Medicin - - 2024
New generation ultra-fast fluorescence confocal microscopy (UFCM) allows to image histological architecture of fresh breast tissue and may be used for ex vivo intraoperative analysis for margin status. The criteria to identify breast tumoral and non-tumoral tissues in UFCM images are still objects of investigation. The objective of the study was to create an atlas of ex vivo UFCM images of breast tissues and breast carcinomas based on the first extensive collection of large field-of-view UFCM breast images. One hundred sixty patients who underwent conserving surgery for breast cancer were included. Their fresh surgical specimens were sliced, stained with acridine orange, and imaged at high resolution with large-field-of-view UFCM. The resulting images were digitally false colored to resemble frozen sections. Each UFCM image was correlated with the corresponding definitive histology. Representative images of normal tissue, inflammation, benign lesions, invasive carcinoma (IC), and ductal carcinoma in situ (DCIS) were collected. A total of 320 large-field images were recorded from 58 IC of no special type, 44 invasive lobular carcinomas, 1 invasive mucinous carcinoma, 47 DCIS, 2 lobular carcinomas in situ, and 8 specimens without cancer. Representative images of the main components of the normal breast and the main types of ICs and DCIS were annotated to establish an UFCM atlas. UFCM enables the imaging of the fresh breast tissue sections. Main morphological criteria defined in traditional histopathology such as tissue architecture and cell features can be applied to describe UFCM images content. The generated atlas of the main normal or tumoral tissue features will support the adoption of this optical technology for the intraoperative examination of breast specimens in clinical practice as it can be used to train physicians on UFCM images and develop artificial intelligence algorithms. Further studies are needed to document rare breast lesions.
Invitation of the 19th European Congress of Pathology
Archiv für pathologische Anatomie und Physiologie und für klinische Medicin - Tập 442 - Trang 527-528 - 2003
Postmodernism and the decline of the clinical autopsy
Archiv für pathologische Anatomie und Physiologie und für klinische Medicin - Tập 479 Số 4 - Trang 861-863 - 2021
Zum 100. geburtstag Robert Rössles
Archiv für pathologische Anatomie und Physiologie und für klinische Medicin - Tập 371 - Trang 1-4 - 1976
Zur Anatomie der Nebennieren
Archiv für pathologische Anatomie und Physiologie und für klinische Medicin - Tập 109 - Trang 324-346 - 1887
Early histologic findings of pulmonary SARS-CoV-2 infection detected in a surgical specimen
Archiv für pathologische Anatomie und Physiologie und für klinische Medicin - - 2020
Despite the current pandemic season, reports on pathologic features of coronavirus disease 19 (Covid-19) are exceedingly rare at the present time. Here we describe the pathologic features of early lung involvement by Covid-19 in a surgical sample resected for carcinoma from a patient who developed SARS-CoV-2 infection soon after surgery. The main histologic findings observed were pneumocyte damage, alveolar hemorrhages with clustering of macrophages, prominent and diffuse neutrophilic margination within septal vessels, and interstitial inflammatory infiltrates, mainly represented by CD8+ T lymphocytes. These features are similar to those previously described in SARS-CoV-1 infection. Subtle histologic changes suggestive pulmonary involvement by Covid-19 may be accidentally encountered in routine pathology practice, especially when extensive sampling is performed for histology. These findings should be carefully interpreted in light of the clinical context of the patient and could prompt a pharyngeal swab PCR test to rule out the possibility of SARS-CoV-2 infection in asymptomatic patients.
Die Harnbestandtheile bei Morb. Addisonii
Archiv für pathologische Anatomie und Physiologie und für klinische Medicin - Tập 56 - Trang 27-37 - 1872
Ueber die chemische Zusammensetzung der Echinococcenflüssigkeit
Archiv für pathologische Anatomie und Physiologie und für klinische Medicin - Tập 63 Số 3-4 - Trang 560-564 - 1875
Tổng số: 14,445
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