Anti-Cancer Agents in Medicinal Chemistry

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Marine Peptides and Related Compounds in Clinical Trial+
Anti-Cancer Agents in Medicinal Chemistry - Tập 6 Số 1 - Trang 33-40 - 2006
Diwan S. Rawat, Mukesh C. Joshi, Penny Joshi, Himanshu Atheaya
Advances in the sophisticated instruments for the isolation and characterization of marine natural products, and development in the biological assay systems, have resulted in the discovery of various compounds of biomedical application. Marine natural products have been a source of new leads for the treatment of many deadly diseases such as cancer, acquired immuno-deficiency syndrome (AIDS) etc. T... hiện toàn bộ
TPEN Exerts Antitumor Efficacy in Murine Mammary Adenocarcinoma Through an H2O2 Signaling Mechanism Dependent on Caspase-3
Anti-Cancer Agents in Medicinal Chemistry - Tập 18 Số 11 - Trang 1617-1628 - 2019
Viviana Soto‐Mercado, Miguel Mendivil‐Perez, Claudia Urueña-Pinzon, Susana Fiorentino, Carlos Vélez-Pardo, Marlene Jiménez-Del-Río
Background: Breast cancer is the second most common cancer worldwide. N, N, N’, N’-Tetrakis (2-pyridylmethyl)-ethylenediamine (TPEN) is a lipid-soluble zinc metal chelator that induces apoptosis in cancer cells through oxidative stress (OS). However, the effectiveness and the mechanisms involved in TPENinduced cell death in mammary adenocarcinoma cells in vitro and in vivo are still unclear. Objec... hiện toàn bộ
Plant Coumestans: Recent Advances and Future Perspectives in Cancer Therapy
Anti-Cancer Agents in Medicinal Chemistry - Tập 14 Số 10 - Trang 1351-1362 - 2014
Tereza Nehybová, Jan Šmarda, Petr Beneš
Brachytherapy: State of the Art and Possible Improvements
Anti-Cancer Agents in Medicinal Chemistry - Tập 7 Số 4 - Trang 411-424 - 2007
S. Buono, N. Burgio, Misara Hamoudeh, Hatem Fessi, E. Hiltbrand, Luca Maciocco, S. Mehier-Humbert
Cancer often remains an incurable disease, despite significant progresses in diagnosis and treatment that have been made. Specifically, the use of nuclear medicine in oncology is greatly contributing to both imaging and therapy aspects. Targeted therapies are a major field of interest since it increases efficiency and reduces side effects. Brachytherapy is among the most valuable of recent develop... hiện toàn bộ
Recent Researches in Metal Supramolecular Complexes as Anticancer Agents
Anti-Cancer Agents in Medicinal Chemistry - Tập 10 Số 5 - Trang 371-395 - 2010
Cheng‐He Zhou, Yiyi Zhang, Cong-Yan Yan, Kun Wan, Lin‐Ling Gan, Yuan Shi
The research and development of metal supramolecular complexes as anticancer supramolecular drugs, which are aggregates mainly formed by one or more inorganic metal compounds with one or more either inorganic or organic molecules in general via coordination bonds, has been a quite rapidly developing, increasingly active and newly rising highlight interdisciplinary field. Numerous efforts have been... hiện toàn bộ
Antidepressant Desipramine Leads to C6 Glioma Cell Autophagy: Implication for the Adjuvant Therapy of Cancer
Anti-Cancer Agents in Medicinal Chemistry - Tập 13 Số 2 - Trang 254-260 - 2013
Jin Ma, Lina Hou, Zhengxing Rong, Liang Peng, Chao Fang, Huafang Li, Hong Qi, Hongzhuan Chen
Urea Derivatives as Anticancer Agents
Anti-Cancer Agents in Medicinal Chemistry - Tập 9 Số 4 - Trang 471-480 - 2009
Huan‐Qiu Li, Peng‐Cheng Lv, Tao Yan, Hai‐Liang Zhu
Within the past ten years, a huge volume of research on the synthesis, structure-activity relationships (SAR), and anticancer activities of the urea derivatives was reported. Many aromatic urea derivatives such as N-phenyl-N-(2-chloroethyl)ureas (CEUs) and benzoylureas (BUs) show good anticancer activity, and these compounds have mainly been proved to be tubulin ligands that inhibit the polymeriza... hiện toàn bộ
Peptide Phage Display: Opportunities for Development of Personalized Anti-Cancer Strategies
Anti-Cancer Agents in Medicinal Chemistry - Tập 6 Số 1 - Trang 9-17 - 2002
Tatiana I. Samoylova, Nancy E. Morrison, Ludmila Globa, Nancy R. Cox
Personalized medicine is critical for cancer patients, because (1) cancer is a highly heterogeneous disease with major molecular differences in the expression and distribution of tumor cell surface markers among patients with the same type and grade of cancer, (2) cellular mutations tend to accumulate as cancer progresses, further increasing tumor heterogeneity, and (3) currently used cancer thera... hiện toàn bộ
The Use of Lentinan for Treating Gastric Cancer
Anti-Cancer Agents in Medicinal Chemistry - Tập 13 Số 5 - Trang 681-688 - 2013
Kenji Ina, Takae Kataoka, Takafumi Ando
Synthesis and Antiproliferative Effects of 5,6-Disubstituted Pyridazin-3(2H)-ones Designed as Conformationally Constrained Combretastatin A-4 Analogues
Anti-Cancer Agents in Medicinal Chemistry - Tập 13 Số 7 - Trang 1133-1140 - 2013
Mohamed Elagawany, Martine Schmitt, Adel Ghiaty, Abd-Allah S. El-Etrawy, M. K. A. IBRAHIM, Frédéric Bihel, Aline Borba Sbardelotto, Cláudia Pessoa, Tam Nguyen, Ernest Hamel, Jean Bourguignon
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