Annual Review of Nutrition

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Single-Subject Studies in Translational Nutrition Research
Annual Review of Nutrition - Tập 37 Số 1 - Trang 395-422 - 2017
Nicholas J. Schork, Laura H. Goetz
There is a great deal of interest in personalized, individualized, or precision interventions for disease and health-risk mitigation. This is as true of nutrition-based intervention and prevention strategies as it is for pharmacotherapies and pharmaceutical-oriented prevention strategies. Essentially, technological breakthroughs have enabled researchers to probe an individual's unique gene...... hiện toàn bộ
TOXIC AND ESSENTIAL METAL INTERACTIONS
Annual Review of Nutrition - Tập 17 Số 1 - Trang 37-50 - 1997
Robert A. Goyer
▪ Abstract  Cadmium, lead, mercury, and aluminum are toxic metals that may interact metabolically with nutritionally essential metals. Iron deficiency increases absorption of cadmium, lead, and aluminum. Lead interacts with calcium in the nervous system to impair cognitive development. Cadmium and aluminum interact with calcium in the skeletal system to produce osteodystrophies. Lead repla...... hiện toàn bộ
Effects of Brain Evolution on Human Nutrition and Metabolism
Annual Review of Nutrition - Tập 27 Số 1 - Trang 311-327 - 2007
William R. Leonard, J. Josh Snodgrass, Marcia L. Robertson
The evolution of large human brain size has had important implications for the nutritional biology of our species. Large brains are energetically expensive, and humans expend a larger proportion of their energy budget on brain metabolism than other primates. The high costs of large human brains are supported, in part, by our energy- and nutrient-rich diets. Among primates, relative brain s...... hiện toàn bộ
The Behavioral Determinants of Exercise: Implications for Physical Activity Interventions
Annual Review of Nutrition - Tập 20 Số 1 - Trang 21-44 - 2000
Robert W. Jeffery
In light of the well-documented health benefits of physical activity and the fact that the majority of adult men and women are inactive, promoting regular physical activity is a public health priority. This chapter reviews current research findings regarding the determinants of exercise behavior. It also discusses the implications of this knowledge for individual and public health recomme...... hiện toàn bộ
Saturated Fats Versus Polyunsaturated Fats Versus Carbohydrates for Cardiovascular Disease Prevention and Treatment
Annual Review of Nutrition - Tập 35 Số 1 - Trang 517-543 - 2015
Patty W. Siri‐Tarino, Sally Chiu, Nathalie Bergeron, Ronald M. Krauss
The effects of saturated fatty acids (SFAs) on cardiovascular disease (CVD) risk are modulated by the nutrients that replace them and their food matrices. Replacement of SFAs with polyunsaturated fatty acids has been associated with reduced CVD risk, although there is heterogeneity in both fatty acid categories. In contrast, replacement of SFAs with carbohydrates, particularly sugar, has ...... hiện toàn bộ
Structure-Function of CD36 and Importance of Fatty Acid Signal Transduction in Fat Metabolism
Annual Review of Nutrition - Tập 34 Số 1 - Trang 281-303 - 2014
Marta Yanina Pepino, Ondřej Kuda, Dmitri Samovski, Nada A. Abumrad
CD36 (cluster of differentiation 36) is a scavenger receptor that functions in high-affinity tissue uptake of long-chain fatty acids (FAs) and contributes under excessive fat supply to lipid accumulation and metabolic dysfunction. This review describes recent evidence regarding the CD36 FA binding site and a potential mechanism for FA transfer. It also presents the view that CD36 and FA s...... hiện toàn bộ
IRON REGULATORY PROTEINS AND THE MOLECULAR CONTROL OF MAMMALIAN IRON METABOLISM
Annual Review of Nutrition - Tập 20 Số 1 - Trang 627-662 - 2000
Richard S. Eisenstein
▪ Abstract  Mammalian iron homeostasis is maintained through the concerted action of sensory and regulatory networks that modulate the expression of proteins of iron metabolism at the transcriptional and/or post-transcriptional levels. Regulation of gene transcription provides critical developmental, cell cycle, and cell-type-specific controls on iron metabolism. Post-transcriptional cont...... hiện toàn bộ
NUTRITIONALIMPACT OFPRE- ANDPROBIOTICS ASPROTECTIVEGASTROINTESTINALORGANISMS
Annual Review of Nutrition - Tập 22 Số 1 - Trang 107-138 - 2002
Jonathan E. Teitelbaum, W. Allan Walker
▪ Abstract  The health benefits of pre- and probiotics have been the subject of increased research interests. These food supplements have been demonstrated to alter the pre-existing intestinal flora so as to provide an advantage to the host. This review focuses on the scientific evidence both for and against their role in promoting health and treating disease. Specific attention is turned ...... hiện toàn bộ
The Emerging Role of microRNAs and Nutrition in Modulating Health and Disease
Annual Review of Nutrition - Tập 34 Số 1 - Trang 305-336 - 2014
Sharon A. Ross, Cindy D. Davis
Understanding the molecular mechanisms that inform how diet and dietary supplements influence health and disease is an active research area. One such mechanism concerns the role of diet in modulating the activity and function of microRNAs (miRNAs). miRNAs are small noncoding RNA molecules that are involved in posttranscriptional gene silencing and have been shown to control gene expressio...... hiện toàn bộ
BIOLOGIC MECHANISMS OF THE PROTECTIVE ROLE OF LUTEIN AND ZEAXANTHIN IN THE EYE
Annual Review of Nutrition - Tập 23 Số 1 - Trang 171-201 - 2003
Norman I. Krinsky, John T. Landrum, Richard A. Bone
▪ Abstract  The macular region of the primate retina is yellow in color due to the presence of the macular pigment, composed of two dietary xanthophylls, lutein and zeaxanthin, and another xanthophyll, meso-zeaxanthin. The latter is presumably formed from either lutein or zeaxanthin in the retina. By absorbing blue-light, the macular pigment protects the underlying photoreceptor cell laye...... hiện toàn bộ
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