Annual Review of Genetics

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Estimating F-Statistics
Annual Review of Genetics - Tập 36 Số 1 - Trang 721-750 - 2002
B. S. Weir, William G. Hill
▪ Abstract  A moment estimator of θ, the coancestry coefficient for alleles within a population, was described by Weir & Cockerham in 1984 ( 100 ) and is still widely cited. The estimate is used by population geneticists to characterize population structure, by ecologists to estimate migration rates, by animal breeders to describe genetic variation, and by forensic scientists to quantify the stren... hiện toàn bộ
MODULATION OF MUTAGENESIS BY DEOXYRIBONUCLEOTIDE LEVELS
Annual Review of Genetics - Tập 25 Số 1 - Trang 339-359 - 1991
Bernard A. Kunz, Susanne E. Kohalmi
XERODERMA PIGMENTOSUM: BIOCHEMICAL AND GENETIC CHARACTERISTICS
Annual Review of Genetics - Tập 9 Số 1 - Trang 19-38 - 1975
James E. Cleaver, D. Bootsma
The Rules of Engagement in the Legume-Rhizobial Symbiosis
Annual Review of Genetics - Tập 45 Số 1 - Trang 119-144 - 2011
Giles Oldroyd, Jeremy D. Murray, Philip S. Poole, J. Allan Downie
Rhizobial bacteria enter a symbiotic association with leguminous plants, resulting in differentiated bacteria enclosed in intracellular compartments called symbiosomes within nodules on the root. The nodules and associated symbiosomes are structured for efficient nitrogen fixation. Although the interaction is beneficial to both partners, it comes with rigid rules that are strictly enforced by the ... hiện toàn bộ
Multiple Roles for Heterochromatin Protein 1 Genes inDrosophila
Annual Review of Genetics - Tập 43 Số 1 - Trang 467-492 - 2009
Danielle Vermaak, Harmit S. Malik
Heterochromatin is the gene-poor, transposon-rich, late-replicating chromatin compartment that was first cytologically defined more than 70 years ago. The identification of heterochromatin protein 1 (HP1) paved the way for a molecular dissection of this important component of complex eukaryotic genomes. Although initial studies revealed HP1's key role in heterochromatin maintenance and function, m... hiện toàn bộ
Rules of Engagement: Molecular Insights from Host-Virus Arms Races
Annual Review of Genetics - Tập 46 Số 1 - Trang 677-700 - 2012
Matthew D. Daugherty, Harmit S. Malik
Mammalian genes and genomes have been shaped by ancient and ongoing challenges from viruses. These genetic imprints can be identified via evolutionary analyses to reveal fundamental details about when (how old), where (which protein domains), and how (what are the functional consequences of adaptive changes) host-virus arms races alter the proteins involved. Just as extreme amino acid conservation... hiện toàn bộ
TOWARDS A GENETIC DISSECTION OF THE BASIS OF TRIPLET DECODING, AND ITS NATURAL SUBVERSION: Programmed Reading Frame Shifts and Hops
Annual Review of Genetics - Tập 25 Số 1 - Trang 201-228 - 1991
John F. Atkins, Robert B. Weiss, S. Thompson
PROGRAMMED TRANSLATIONAL FRAMESHIFTING
Annual Review of Genetics - Tập 30 Số 1 - Trang 507-528 - 1996
Philip J. Farabaugh
▪ Abstract  Errors that alter the reading frame occur extremely rarely during translation, yet some genes have evolved sequences that efficiently induce frameshifting. These sequences, termed programmed frameshift sites, manipulate the translational apparatus to promote non-canonical decoding. Frameshifts are mechanistically diverse. Most cause a −1 shift of frames; the first such site was discove... hiện toàn bộ
Plant Virus Metagenomics: Biodiversity and Ecology
Annual Review of Genetics - Tập 46 Số 1 - Trang 359-369 - 2012
Marilyn J. Roossinck
Viral metagenomics is the study of viruses in environmental samples, using next generation sequencing that produces very large data sets. For plant viruses, these studies are still relatively new, but are already indicating that our current knowledge grossly underestimates the diversity of these viruses. Some plant virus studies are using thousands of individual plants so that each sequence can be... hiện toàn bộ
Shufflons: Multiple Inversion Systems and Integrons
Annual Review of Genetics - Tập 33 Số 1 - Trang 171-191 - 1999
Teruya Komano
▪ Abstract  Conservative site-specific recombination functions to create biological diversity in prokaryotes. Simple site-specific recombination systems consist of two recombination sites and a recombinase gene. The plasmid R64 shufflon contains seven recombination sites, which flank and separate four DNA segments. Site-specific recombinations mediated by the product of the rci gene between any tw... hiện toàn bộ
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