Downregulation of telomerase activity in human promyelocytic cell line using RNA interferenceAnnals of Hematology - Tập 88 - Trang 1169-1176 - 2009
E. Miri-Moghaddam, A. Deezagi, Z. S. Soheili
Telomerase is a ribonucleoprotein complex. It consists of two main components, human telomerase reverse transcriptase (hTERT) and human telomerase RNA. High telomerase activity is present in most malignant cells, but it is barely detectable in majority of somatic cells. The direct correlation between telomerase reactivation and carcinogens has made hTERT a key target for anticancer therapeutic stu...... hiện toàn bộ
A new sarcomatoid variant of multiple myeloma in a 20-year-old maleAnnals of Hematology - Tập 83 - Trang 251-252 - 2003
I. C. Gauer, V. Hagen, H. Merz
We present a 20-year-old man with a rare variant of multiple myeloma with peculiar spindle cell morphology and sarcomatoid growth. The diagnosis of multiple myeloma was substantiated by clinical examinations. The patient was treated with several therapeutic trials including autologous stem cell support. Unfortunately, he developed a disseminated aspergillosis of the lungs and died of fatal lung bl...... hiện toàn bộ
Severe aplastic anemia associated with thymic carcinoma and partial recovery of hematopoiesis after thymectomyAnnals of Hematology - Tập 82 - Trang 367-370 - 2003
K. Koizumi, S. Nakao, Y. Haseyama, H. Kato, M. Ohi, T. Motohara, T. Endo, K. Sawada, T. Koike
Aplastic anemia has been a rare complication of thymic tumors documented in only a few cases. We now report that a previously healthy, 72-year-old woman had a well-differentiated squamous cell thymic carcinoma and severe aplastic anemia, as detected on a simultaneous basis. After extirpation of the thymic carcinoma, hematological recovery was achieved. While cyclosporine (CyA), prednisolone (PSL),...... hiện toàn bộ
Die elektrophoretische Beweglichkeit der Blutlymphozyten bei chronischer lymphatischer LeukämieAnnals of Hematology - Tập 35 - Trang 135-142 - 1977
J. C. F. Schubert, K. Schopow, F. Walther
Lymphozyten und andere Blutzellen können mit der trägerfreien Zellelektrophorese getrennt werden. Im Normalblut ergibt die Charakterisierung der getrennten Lymphozyten mit den fluoreszenzmarkierten Antiglobulinen IgD und IgM verschiedene Verteilungsprofile für jede Immunglobulinklasse, wobei die IgD-positiven Zellen schneller wandern als die IgM-positiven. Im Vergleich dazu wurden 5 Patienten mit ...... hiện toàn bộ
BuchbesprechungenAnnals of Hematology - Tập 27 - Trang 62-63 - 1973
E. Kleihauer, D. Huhn, H. Rieg, D. L. Heene, Th. Rippich
Intensive care unit admission in patients with T cell lymphomas: clinical features and outcomeAnnals of Hematology - Tập 98 - Trang 195-203 - 2018
Guillaume Dumas, Lucie Biard, Claire Givel, Sandy Amorim, Lara Zafrani, Virginie Lemiale, Eric Mariotte, Elie Azoulay, Catherine Thiéblemont, Emmanuel Canet
T cell non-Hodgkin lymphomas (T-NHLs) are aggressive malignancies which have a high risk of life-threatening complications. However, their prognosis in the intensive care unit (ICU) setting has not yet been assessed. We conducted a study including 87 ICU patients either with newly diagnosed T-NHLs or those undergoing first-line therapy admitted between January 1, 2000, and December 31, 2014. The p...... hiện toàn bộ