Angiogenesis
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Circulating Basic Fibroblast Growth Factor is Partly Derived from the Tumour in Patients with Colon, Cervical and Ovarian Cancer
Angiogenesis - Tập 7 - Trang 29-32 - 2004
In order to investigate whether the high bFGF serum levels encountered in cancer patients are derived from the tumour, we analysed serum bFGF levels in 18 untreated randomly selected patients with operable colorectal, cervical and ovarian cancer in the blood draining the tumour, i.e., in mesenteric and uterine veins, and compared these with arterial samples. No significantly elevated bFGF levels w...... hiện toàn bộ
Interferon-alpha or -beta facilitates SARS-CoV-2 pulmonary vascular infection by inducing ACE2Abstract Severe viral pneumonia caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is characterized by a hyperinflammatory state typified by elevated circulating pro-inflammatory cytokines, frequently leading to potentially lethal vascular complications including thromboembolism, disseminated intracellular coagulopathy and vasculitis. Though ... ... hiện toàn bộ
Angiogenesis - Tập 25 Số 2 - Trang 225-240 - 2022
CM101 stimulates cutaneous wound healing through an anti-angiogenic mechanism
Angiogenesis - Tập 4 - Trang 61-70 - 2001
CM101, an anti-pathoangiogenic polysaccharide derived from group B streptococcus, has been shown to inhibit inflammatory angiogenesis and accelerate wound healing in a mouse model and minimize scarring/gliosis following spinal cord injury. To evaluate the in vivo effects of CM101 on cutaneous wound healing in the pig, intravenously delivered CM101 or placebo vehicle was given 1 h after cutaneous w...... hiện toàn bộ
PPAR $$\upgamma$$ represses VEGF expression in human endometrial cells: Implications for uterine angiogenesis
Angiogenesis - Tập 8 - Trang 373-379 - 2006
Endometrial vasculature supports physiological uterine growth, embryonic implantation and endometrial pathology. Vascular endothelial growth factor (VEGF) is regulated by diverse developmental and hormonal signals, including eicosanoid ligands of PPAR
$$\upgamma$$
. The action of natural and synthetic PPAR
$$\upgamma$$
ligands on...... hiện toàn bộ
Inflammation and vascular remodeling in COVID-19 hearts
Angiogenesis - Tập 26 - Trang 233-248 - 2022
A wide range of cardiac symptoms have been observed in COVID-19 patients, often significantly influencing the clinical outcome. While the pathophysiology of pulmonary COVID-19 manifestation has been substantially unraveled, the underlying pathomechanisms of cardiac involvement in COVID-19 are largely unknown. In this multicentre study, we performed a comprehensive analysis of heart samples from 24...... hiện toàn bộ
Abstracts of the Euroconference Angiogenesis II Institut Pasteur, Paris, France 19–20 June 2003
Angiogenesis - - 2003
Exacerbated inflammatory signaling underlies aberrant response to BMP9 in pulmonary arterial hypertension lung endothelial cells
Angiogenesis - Tập 23 - Trang 699-714 - 2020
Imbalanced transforming growth factor beta (TGFβ) and bone morphogenetic protein (BMP) signaling are postulated to favor a pathological pulmonary endothelial cell (EC) phenotype in pulmonary arterial hypertension (PAH). BMP9 is shown to reinstate BMP receptor type-II (BMPR2) levels and thereby mitigate hemodynamic and vascular abnormalities in several animal models of pulmonary hypertension (PH). ...... hiện toàn bộ
The formation of tubular structures by endothelial cells is under the control of fibrinolysis and mechanical factors
Angiogenesis - Tập 2 - Trang 331-344 - 1998
This study highlights the importance of several factors involved in the formation of capillary-like structure formation (CLS) using Human Umbilical Vein Endothelial Cells (HUVEC) and Bovine Retinal Endothelial Cells (BREC) cultured on fibrin gels. The fibrin concentration inducing (CLS) was 0.5 mg/ml for HUVEC and 8 mg/ml for BREC. The high fibrin concentration required for the latter cells appear...... hiện toàn bộ
Progestogen only contraception and endometrial break through bleeding
Angiogenesis - Tập 8 - Trang 117-126 - 2005
Progestogen only contraceptives (POC) provide a safe and effective method of fertility regulation. Unfortunately, they are commonly associated with the problem of endometrial break through bleeding (BTB), often leading to discontinuation of use. An increase in endometrial vascular fragility has been demonstrated as an important mechanism that contributes to BTB but our understanding of the interac...... hiện toàn bộ
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