American Society of Clinical Oncology (ASCO)

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Lymphovascular Invasion Predicts Clinical Outcomes in Patients With Node-Negative Upper Tract Urothelial Carcinoma
American Society of Clinical Oncology (ASCO) - Tập 27 Số 4 - Trang 612-618 - 2009
Eiji Kikuchi, Vitaly Margulis, Pierre I. Karakiewicz, Marco Roscigno, Shuji Mikami, Yair Lotan, Mesut Remzi, Christian Bolenz, Cord Langner, Alon Z. Weizer, Francesco Montorsi, Karim Bensalah, Theresa M. Koppie, Mario I. Fernández, Jay D. Raman, Wassim Kassouf, Christopher G. Wood, Nazareno Suardi, Mototsugu Oya, Shahrokh F. Shariat
Purpose To assess the association of lymphovascular invasion (LVI) with cancer recurrence and survival in a large international series of patients treated with radical nephroureterectomy (RNU) for upper urinary tract urothelial carcinoma (UTUC). Patients and Methods Data were collected on 1,45...... hiện toàn bộ
Long-term disease-free survival in small-cell carcinoma of the lung: a study of clinical determinants.
American Society of Clinical Oncology (ASCO) - Tập 4 Số 9 - Trang 1307-1313 - 1986
Kell Østerlind, Heine H. Hansen, Mogens Hansen, P Dombernowsky, Per Kragh Andersen
The influence of treatment and of pretreatment patient characteristics on the probability of long-term disease-free survival in small-cell lung cancer (SCLC) was investigated in a consecutive series of 874 patients. The patients were included in six controlled treatment trials from 1973 to 1981, using different combinations of chemotherapy with or without irradiation. All patients underwe...... hiện toàn bộ
Combined modality induction therapy without maintenance chemotherapy for small cell carcinoma of the lung.
American Society of Clinical Oncology (ASCO) - Tập 2 Số 4 - Trang 294-304 - 1984
Ronald Feld, William K. Evans, Gerrit DeBoer, Ian Quirt, Frances A. Shepherd, J L Yeoh, J Pringle, David G. Payne, James G. Herman, Donald H. Chamberlain
One hundred fifty-three patients with limited and 167 with extensive small cell carcinoma of the lung (SCCL) were evaluable for response to treatment with six courses of chemotherapy (cyclophosphamide, doxorubicin, and vincristine), irradiation to intrathoracic disease, and prophylactic cranial irradiation (PCI). No maintenance chemotherapy was given. Fifty-two percent of patients with li...... hiện toàn bộ
Long-term survival in small-cell carcinoma of the lung: a population experience.
American Society of Clinical Oncology (ASCO) - Tập 3 Số 1 - Trang 80-91 - 1985
Susan R. Davis, Peter Wright, Susan Schulman, Delia Scholes, David Thorning, Samuel P. Hammar
Small-cell lung carcinoma (SCLC) is a rapidly progressive and fatal disease. Historically, surgical resection or radiotherapy of the primary tumor has done little to prolong survival, although the use of combination chemotherapy is more effective. Reported here is the survival experience of 1,538 incident cases of SCLC identified through the Surveillance, Epidemiology and End Results Prog...... hiện toàn bộ
Treatment of small-cell lung cancer on protocol: potential bias of results.
American Society of Clinical Oncology (ASCO) - Tập 4 Số 9 - Trang 1314-1320 - 1986
Élisabeth Quoix, Harriet Schwartz Finkelstein, N Wolkove, Harvey Kreisman
During a 27-month period, 215 new cases of lung cancer were diagnosed at five McGill University hospitals. Only 44 patients (20%) so diagnosed were treated on available chemotherapy protocols. Six categories were used to define reasons for nonparticipation. The most important were medical reasons (MRs), 46%; non-medical reasons (NMRs), 20%; and physician preference (PP), 16%. The three re...... hiện toàn bộ
Long-Term Survival in Metastatic Transitional-Cell Carcinoma and Prognostic Factors Predicting Outcome of Therapy
American Society of Clinical Oncology (ASCO) - Tập 17 Số 10 - Trang 3173-3181 - 1999
Dean F. Bajorin, Paul M. Dodd, Madhu Mazumdar, Melissa Fazzari, John A. McCaffrey, Howard I. Scher, Harry W. Herr, Geralyn Higgins, Mary G. Boyle
PURPOSE: The variation in reported survival of patients with metastatic transitional-cell carcinoma (TCC) treated with systemic chemotherapy may be a consequence of pretreatment patient characteristics. We hypothesized that a prognostic factor–based model of survival among patients treated with methotrexate, vinblastine, doxorubicin, and cisplatin chemotherapy could account for such diffe...... hiện toàn bộ
Positron Emission Tomography/Computed Tomography Identification of Clear Cell Renal Cell Carcinoma: Results From the REDECT Trial
American Society of Clinical Oncology (ASCO) - Tập 31 Số 2 - Trang 187-194 - 2013
Chaitanya Divgi, Robert G. Uzzo, Constantine Gatsonis, Roman Bartz, Silke Treutner, Jian Q. Yu, Ying‐Bei Chen, Jorge A. Carrasquillo, Steven M. Larson, Paul Bevan, Paul Russo
Purpose A clinical study to characterize renal masses with positron emission tomography/computed tomography (PET/CT) was undertaken. Patients and Methods This was an open-label multicenter study of iodine-124 (124I) -girentuximab PET/CT in patients with renal masses who we...... hiện toàn bộ
Antibody localization in human renal cell carcinoma: a phase I study of monoclonal antibody G250.
American Society of Clinical Oncology (ASCO) - Tập 11 Số 4 - Trang 738-750 - 1993
Egbert Oosterwijk, Neil H. Bander, C R Divgi, Sydney Welt, Jeannette C. Wakka, Ronald D. Finn, E A Carswell, Steven M. Larson, S. O. Warnaar, Gert Jan Fleuren
PURPOSE To define the imaging and biodistribution characteristics of iodine 131-labeled monoclonal antibody (mAb) G250 (131I-mAbG250), which recognizes a cell-surface antigen expressed by human renal cell carcinoma (RCC). PATIENTS AND METHODS G250 is a cell-surface antigen recognized by mAbG25...... hiện toàn bộ
Lack of Efficacy of Two Consecutive Treatments of Radioimmunotherapy With 131I-cG250 in Patients With Metastasized Clear Cell Renal Cell Carcinoma
American Society of Clinical Oncology (ASCO) - Tập 23 Số 27 - Trang 6540-6548 - 2005
Adrienne H. Brouwers, Peter F.A. Mulders, P.H.M. de Mulder, Wim J.M. van den Broek, W C Buijs, C. Mala, F.B.M. Joosten, Egbert Oosterwijk, Otto C. Boerman, Frans H.M. Corstens, Wim J.G. Oyen
Purpose A previous activity dose-escalation study using 131I-labeled chimeric monoclonal antibody cG250 in patients with progressive metastatic renal cell carcinoma (RCC) resulted in occasional therapeutic responses. The present study was designed to determine the safety and therapeutic efficacy of two sequential high-dose treatments ...... hiện toàn bộ
Carbonic Anhydrase IX Is Not an Independent Predictor of Outcome for Patients With Clear Cell Renal Cell Carcinoma
American Society of Clinical Oncology (ASCO) - Tập 25 Số 30 - Trang 4757-4764 - 2007
Bradley C. Leibovich, Yuri Sheinin, Christine M. Lohse, R. Houston Thompson, John C. Cheville, J Závada, Eugene D. Kwon
Purpose Expression of carbonic anhydrase IX (CAIX) has been reported to be an independent predictor of outcome and is being investigated as a therapeutic target for patients with clear cell renal cell carcinoma (ccRCC). We attempted to validate the prognostic utility of CAIX expression using a large cohort of ccRCC patients with long-term follow-up. ... hiện toàn bộ
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