American Journal of Nephrology
SCOPUS (1981-2025)SCIE-ISI
1421-9670
0250-8095
Thụy Sĩ
Cơ quản chủ quản: KARGER , S. Karger AG
Lĩnh vực:
Nephrology
Các bài báo tiêu biểu
Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review
Tập 45 Số 2 - Trang 160-169 - 2017
Background: Cancer immunotherapy, such as anti-cytotoxic
T-lymphocyte-associated protein 4 (CTLA-4) and anti-programmed death 1 (PD-1),
has revolutionized the treatment of malignancies by engaging the patient's own
immune system against the tumor rather than targeting the cancer directly. These
therapies have demonstrated a significant benefit in the treatment of melanomas
and other ...
Hepatitis B Virus-Associated Nephropathy
Tập 24 Số 2 - Trang 198-211 - 2004
A direct causal association between hepatitis B virus (HBV) infection and the
development of nephropathy remains controversial. Epidemiological studies have
shown that chronic carriage of HBV in some individuals (particularly children)
leads to the development of nephrotic syndrome with a strong male predominance,
the commonest histological type being membranous nephropathy (MN). Spontaneous
clear...
Assessment of the Efficacy and Safety of Intravenous Conivaptan in Euvolemic and Hypervolemic Hyponatremia
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Background: Most cases of hyponatremia – serum sodium concentration
([Na+]) <135 mEq/l (<135 mM) – are associated with an elevated
plasma arginine vasopressin level. This study investigated the efficacy and
tolerability of intravenous conivaptan (YM087), a vasopressin
V1A/V2-receptor antagonist, in treating euvolemic and
hypervolemic hyponatremia. ...
Acute Hydrothorax in Continuous Ambulatory Peritoneal Dialysis – A Collaborative Study of 161 Centers
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Calcineurin Inhibitor Nephrotoxicity: A Review and Perspective of the Evidence
Tập 37 Số 6 - Trang 602-612 - 2013
Background: There is no doubt that acute calcineurin inhibitor
(CNI) nephrotoxicity exists; however, chronic CNI nephrotoxicity is questionable
at best. Methods: We reviewed the literature to identify original
articles related to the use of CNIs in renal and nonrenal solid organ
transplantation in order to examine the available evidence about their chronic
nephrotoxicit...
Indoxyl Sulfate Inhibits Nitric Oxide Production and Cell Viability by Inducing Oxidative Stress in Vascular Endothelial Cells
Tập 29 Số 6 - Trang 551-557 - 2009
Background/Aim: Cardiovascular disease is a major cause of mortality in
chronic kidney disease patients. Oxidative stress and nitric oxide (NO)
deficiency play an important role in vascular endothelial cell dysfunction in
chronic kidney disease. To determine if the uremic toxin indoxyl sulfate (IS)
induces oxidative stress and inhibits NO production and cell viability in human
umbilical vei...
Predictors of Hyperkalemia Risk following Hypertension Control with Aldosterone Blockade
Tập 30 Số 5 - Trang 418-424 - 2009
Background: Aldosterone antagonists have proven efficacy for management
of resistant hypertension and proteinuria reduction; however, they are not
widely used due to risk of hyperkalemia. This study assesses the risk factors
for hyperkalemia in patients with chronic kidney disease (CKD) and resistant
hypertension whose blood pressure (BP) is reduced to a guideline goal.
Methods: This...
Renal Biopsy in 2015 - From Epidemiology to Evidence-Based Indications
Tập 43 Số 1 - Trang 1-19 - 2016
Background: Although the number of patients reaching end-stage
kidney disease without a biopsy-proven diagnosis is increasing, the utility of
renal biopsy is still an object of debate. We analyzed epidemiological data and
the main indications for renal biopsy with a systematic, evidence-based review
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Serum Potassium, End-Stage Renal Disease and Mortality in Chronic Kidney Disease
Tập 41 Số 6 - Trang 456-463 - 2015
Background/Aims: Hypokalemia and hyperkalemia are often noted in
chronic kidney disease (CKD) patients, but their impact on mortality and
end-stage renal disease (ESRD) is less well understood. We aimed at studying the
associations between potassium disorders, and mortality and progression to ESRD
in a CKD population. Methods: Using our electronic health
record-based CK...