American Journal of Clinical Dermatology
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Skin Cancer Following Solid Organ Transplantation: A Review of Risk Factors and Models of Care
American Journal of Clinical Dermatology - Tập 19 - Trang 585-597 - 2018
The number of solid organ transplants has been increasing annually worldwide. Advances in transplantation surgery and community awareness of organ donation have been key contributors. Combined with increased understanding of immunosuppression, there are a growing number of solid organ transplant recipients in the community as a result of improved long-term outcomes. There remains a high incidence ...... hiện toàn bộ
Topical Calcineurin Inhibitors in the Treatment of Atopic Dermatitis
American Journal of Clinical Dermatology - Tập 5 - Trang 267-279 - 2012
Purpose: To summarize success rates of the topical calcineurin inhibitors tacrolimus and pimecrolimus in treating atopic dermatitis.
Methods: Randomized controlled trials (RCTs) comparing either drug to themselves (i.e. dose-ranging studies), each other, the vehicle (or placebo), or corticosteroids were obtained from Medline, EMBASE, and Cochrane databases. Two re...... hiện toàn bộ
Clinical Disease Measures in Generalized Pustular Psoriasis
American Journal of Clinical Dermatology - Tập 23 - Trang 39-50 - 2022
Generalized pustular psoriasis (GPP) is a rare neutrophilic skin condition characterized by episodes of widespread eruption of sterile macroscopic pustules that can be associated with systemic inflammation. The rarity of GPP and its heterogeneous cutaneous and extracutaneous symptoms pose considerable challenges to the development and adoption of comprehensive accurate disease measures for the rou...... hiện toàn bộ
Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails
American Journal of Clinical Dermatology - Tập 19 - Trang 31-39 - 2018
Targeted therapies and immunotherapies are associated with a wide range of dermatologic adverse events (dAEs) resulting from common signaling pathways involved in malignant behavior and normal homeostatic functions of the epidermis and dermis. Dermatologic toxicities include damage to the skin, oral mucosa, hair, and nails. Acneiform rash is the most common dAE, observed in 25–85% of patients trea...... hiện toàn bộ
The Role of Calcineurin Inhibitors in the Management of Lichen Sclerosus
American Journal of Clinical Dermatology - Tập 10 - Trang 313-318 - 2012
Lichen sclerosus is a chronic inflammatory disorder with a propensity to affect the mucocutaneous anogenital area. Topical corticosteroids remain the treatment of choice for this condition and constitute an effective therapeutic modality. However, in patients with corticosteroid-resistant disease, when long-term remission is not sustainable, or in those intolerant to these agents, topical calcineu...... hiện toàn bộ
Cutaneous Psammomatous Melanotic Schwannoma
American Journal of Clinical Dermatology - Tập 4 - Trang 799-802 - 2012
Background: Melanotic schwannoma is a pigmented nerve tumor that may be located in the skin and express local aggressivity. This tumor may occur singly. It may also be part of the Carney complex which consists of various, but specific, tumors.
Objective: We report two cases of subcutaneous melanotic schwannoma localized on the trunk in two men aged 37 and 45 years...... hiện toàn bộ
Global Incidence, Mortality, Risk Factors and Trends of Melanoma: A Systematic Analysis of Registries
American Journal of Clinical Dermatology - Tập 24 - Trang 965-975 - 2023
Melanoma of the skin is the most dangerous skin cancer in the world, though the numbers of reported new cases and melanoma-related deaths are low. This study evaluated the global incidence, mortality, risk factors and temporal trends by age, sex and locations of melanoma skin cancer. Cancer Incidence in Five Continents (CI5) volumes I–XI; the Nordic Cancer Registries (NORDCAN); the Surveillance, E...... hiện toàn bộ
Blue Nail Discoloration: Literature Review and Diagnostic Algorithms
American Journal of Clinical Dermatology - Tập 24 - Trang 419-441 - 2023
Blue nail discoloration is a distinctive clinical presentation, and diagnosis is challenging given the broad differential diagnosis. A comprehensive review of the literature describing blue discoloration of one or multiple nails was performed using the PubMed, Embase, Scopus, and Web of Science databases. A total of 245 publications were included and grouped based on involvement of a single nail (...... hiện toàn bộ
Staphylococcal Scalded Skin Syndrome
American Journal of Clinical Dermatology - - 2012
Staphylococcal scalded skin syndrome (SSSS) is a common disorder that is usually seen in infants and children and rarely seen in adults. SSSS usually presents with a prodrome of sore throat or conjunctivitis. Extremely tender flaccid bullae, which are Nikolsky sign-positive, develop within 48 hours and commonly affect the flexures; occasionally, large areas of the skin may be involved. The bullae ...... hiện toàn bộ
Drug Treatment of Cutaneous Lupus
American Journal of Clinical Dermatology - Tập 1 - Trang 375-379 - 2012
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