Adjuvant Antiarrhythmic Therapy in Patients with Implantable Cardioverter DefibrillatorsAmerican Journal of Cardiovascular Drugs - Tập 14 - Trang 89-100 - 2013
T. Jared Bunch, Jeffrey L. Anderson
The risk of sudden cardiac death from ventricular fibrillation or ventricular tachycardia in patients with cardiomyopathy related to structural heart disease has been favorably impacted by the wide adaptation of implantable cardioverter defibrillators (ICDs) for both primary and secondary prevention. Unfortunately, after ICD implantation both appropriate and inappropriate ICD therapies are common....... hiện toàn bộ
The Cost Effectiveness of Statin Therapies in Spain in 2010, after the Introduction of Generics and Reference PricesAmerican Journal of Cardiovascular Drugs - Tập 10 - Trang 369-382 - 2012
Pedro Plans-Rubió
HMG-CoA reductase inhibitors (statins) are the first-line drugs for use in the reduction of low-density lipoprotein cholesterol (LDL-C) levels and prevention of coronary heart disease (CHD) in patients with hypercholesterolemia. Generic statins could change the cost effectiveness of statin therapies in Spain, and more population groups could be included in the recommendations for reduction of chol...... hiện toàn bộ
Hemodynamic Effects of Sacubitril/Valsartan in Patients with Reduced Left Ventricular Ejection Fraction Over 24 Months: A Retrospective StudyAmerican Journal of Cardiovascular Drugs - Tập 22 - Trang 535-544 - 2022
Mohammad Abumayyaleh, Jonathan Demmer, Carina Krack, Christina Pilsinger, Ibrahim El-Battrawy, Michael Behnes, Assem Aweimer, Andreas Mügge, Siegfried Lang, Ibrahim Akin
The effects of sacubitril/valsartan in patients with chronic heart failure with reduced ejection fraction (HFrEF) were recently reported. However, the hemodynamic impact of this well-established treatment in patients with HFrEF has been poorly systematically researched. We aimed to investigate the hemodynamic effects of sacubitril/valsartan among patients with HFrEF. Between 2016 and 2020, we retr...... hiện toàn bộ
The Effects of HMG-CoA Reductase Inhibitors on Endothelial FunctionAmerican Journal of Cardiovascular Drugs - Tập 6 - Trang 115-120 - 2012
Belay Tesfamariam
Vascular endothelial dysfunction is a complex phenomenon that is caused by an imbalance of vasodilator and vasoconstrictor factors that regulate the equilibrium-maintaining vascular tone. In the early phase of hypercholesterolemia, endothelial dysfunction precedes vascular wall lesions. One of the earliest recognizable benefits of treatment with HMG-CoA reductase inhibitors (statins) is the normal...... hiện toàn bộ
Direct AntithrombinsAmerican Journal of Cardiovascular Drugs - - 2007
Cheuk‐Kit Wong, Harvey D. White
Peroxisome Proliferator-Activated Receptor-β and its Agonists in Hypertension and AtherosclerosisAmerican Journal of Cardiovascular Drugs - Tập 5 - Trang 389-398 - 2012
Carmen M. Halabi, Curt D. Sigmund
Cardiovascular diseases are the leading cause of morbidity and mortality in the US. Proper management and/ or prevention of atherosclerosis and hypertension, two complex and chronic disorders, would significantly reduce the risk for cardiovascular events such as myocardial infarction and stroke, but this requires an understanding of the mechanisms underlying their development and progression. Wher...... hiện toàn bộ
Atrial Fibrillation in Patients with Heart Failure: Current State and Future DirectionsAmerican Journal of Cardiovascular Drugs - Tập 18 - Trang 347-360 - 2018
Tuoyo O. Mene-Afejuku, Persio D. López, Adedoyin Akinlonu, Carissa Dumancas, Ferdinand Visco, Savi Mushiyev, Gerald Pekler
Heart failure affects nearly 26 million people worldwide. Patients with heart failure are frequently affected with atrial fibrillation, and the interrelation between these pathologies is complex. Atrial fibrillation shares the same risk factors as heart failure. Moreover, it is associated with a higher-risk baseline clinical status and higher mortality rates in patients with heart failure. The mec...... hiện toàn bộ