Advances in Rheumatology

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Fibronectin extra domain A as a drug delivery targeting epitope for rheumatoid arthritis
Advances in Rheumatology - - 2022
Victor Sun, Terry Melim, Soumya Mitra, Jon W. Erickson, Shaughn Bryant, Avery Farnham, Susan V. Westmoreland, Heather Knight, Liang Zhang, Wendy Ritacco, Kristoff T. Homan, Lorenzo Benatuil, Annette J. Schwartz Sterman, Andrew Goodearl
Abstract Objectives To assess the ability of monoclonal antibodies (mAbs) specific for fibronectin extra-domain A (FnEDA) to target diseased tissues of mouse collagen induced arthritis (mCIA) models. To explore the parameters of the targeting exhibited by anti-FnEDA mAbs including timing and locatio...... hiện toàn bộ
Safety and immunogenicity of influenza A(H3N2) component vaccine in juvenile systemic lupus erythematosus
Advances in Rheumatology - Tập 63 - Trang 1-7 - 2023
Nadia Emi Aikawa, Eduardo Ferreira Borba, Verena Andrade Balbi, Adriana Maluf Elias Sallum, Izabel Mantovani Buscatti, Lucia Maria Arruda Campos, Kátia Tomie Kozu, Cristiana Couto Garcia, Artur Silva Vidal Capão, Adriana Coracini Tonacio de Proença, Elaine Pires Leon, Alberto José da Silva Duarte, Marta Heloisa Lopes, Clovis Artur Silva, Eloisa Bonfá
Seasonal influenza A (H3N2) virus is an important cause of morbidity and mortality in the last 50 years in population that is greater than the impact of H1N1. Data assessing immunogenicity and safety of this virus component in juvenile systemic lupus erythematosus (JSLE) is lacking in the literature. To evaluate short-term immunogenicity and safety of influenza A/Singapore (H3N2) vaccine in JSLE. ...... hiện toàn bộ
Microparticles: potential new contributors to the pathogenesis of systemic sclerosis?
Advances in Rheumatology - Tập 63 - Trang 1-8 - 2023
Sandra Maximiano de Oliveira, Ighor Luiz de Azevedo Teixeira, Carolina Nunes França, Maria Cristina de Oliveira Izar, Cristiane Kayser
Microparticles (MPs) are membrane-derived vesicles released from cells undergoing activation or apoptosis with diverse proinflammatory and prothrombotic activities, that have been implicated in the pathogenesis of systemic sclerosis (SSc). We aimed to evaluate the plasma levels of platelet-derived microparticles (PMPs), endothelial cell-derived microparticles (EMPs), and monocyte-derived micropart...... hiện toàn bộ
Prevalence of juvenile idiopathic arthritis in schoolchildren from the city of São Paulo, the largest city in Latin America
Advances in Rheumatology - Tập 59 - Trang 1-7 - 2019
Vânia Schinzel, Simone Guerra Lopes da Silva, Maria Teresa Terreri, Claudio Arnaldo Len
Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disease that affects children and adolescents. Its prevalence varies greatly from one study to another according to the population and methodology. Some tools may be helpful in screening for suspected cases. The aim of this study is determine the prevalence of JIA in children and adolescent students in the city of São Paulo, Brazil. Thi...... hiện toàn bộ
Cardiovascular risk assessment using ASCVD risk score in fibromyalgia: a single-centre, retrospective study using “traditional” case control methodology and “novel” machine learning
Advances in Rheumatology - Tập 61 - Trang 1-9 - 2021
Sandeep Surendran, C. B. Mithun, Merlin Moni, Arun Tiwari, Manu Pradeep
In autoimmune inflammatory rheumatological diseases, routine cardiovascular risk assessment is becoming more important. As an increased cardiovascular disease (CVD) risk is recognized in patients with fibromyalgia (FM), a combination of traditional CVD risk assessment tool with Machine Learning (ML) predictive model could help to identify non-traditional CVD risk factors. This study was a retrospe...... hiện toàn bộ
Relationship of the sacral slope with early gait derangements in robust older women
Advances in Rheumatology - Tập 61 - Trang 1-9 - 2021
Leda Magalhaes Oliveira, Suely Roizenblatt, Flavio Duarte Silva, Arnaldo Roizenblatt, Artur Rocha Correa Fernandes, Vera Lucia Szejnfeld
Trunk pelvic dissociation is fundamental to the compensatory mechanism for muscle weakness during body bending. We carried out an early investigation of gait changes in a sample of community-dwelling women ≥60 years without gait complaints. The primary objective was to correlate spine and pelvic angles with performance tests and accelerometry parameters. The secondary objective was to correlate pe...... hiện toàn bộ
Platelet/lymphocyte ratio and mean platelet volume in patients with granulomatosis with polyangiitis
Advances in Rheumatology - Tập 60 - Trang 1-6 - 2019
Hamit Kucuk, Duygu Tecer, Berna Goker, Ozkan Varan, Hakan Babaoglu, Serdar Can Guven, Mehmet Akif Ozturk, Seminur Haznedaroglu, Abdurrahman Tufan
Granulomatosis with polyangiitis (GPA) is a granulomatous necrotizing vasculitis with high morbidity and mortality. Anti-neutrophil cytoplasmic antibody is a valuable diagnostic marker, however its titer lacks predictive value for the severity of organ involvement. Platelet to lymphocyte ratio (PLR) and mean platelet volume (MPV) has been regarded as a potential marker in assessing systemic inflam...... hiện toàn bộ
Serum defensin levels in patients with systemic sclerosis
Advances in Rheumatology - Tập 60 - Trang 1-5 - 2020
Tugce Emiroglu Gedik, Hamit Kucuk, Berna Goker, Seminur Haznedaroglu, Hatice Pasaoglu, Ozkan Varan, Mehmet Akif Ozturk, Ozge Tugce Pasaoglu, Abdurrahman Tufan
Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of skin and lung as well as involvement of kidney, gastrointestinal system and heart. Aetiology and exact mechanism of disease is poorly understood. The association between antimicrobial peptides (AMPs) and other diseases such as idiopathic pulmonary fibrosis, diffuse panbronchiolitis, pulmoner alveolar proteinosis and pso...... hiện toàn bộ
Cardiovascular risk comorbidities in rheumatoid arthritis patients and the use of anti-rheumatic drugs: a cross-sectional real-life study
Advances in Rheumatology - Tập 61 - Trang 1-9 - 2021
Gustavo Nogueira Schincariol Vicente, Ivânio Alves Pereira, Gláucio Ricardo Werner de Castro, Licia Maria Henrique da Mota, Ana Paula Carnieletto, Dhara Giovanna Santin de Souza, Fabiana Oenning da Gama, Ana Beatriz Vargas Santos, Cleandro Pires de Albuquerque, Manoel Barros Bértolo, Paulo Louzada Júnior, Rina Dalva Neubarth Giorgi, Sebastião Cezar Radominski, Maria Fernanda Brandão Resende Guimarães, Karina Rossi Bonfiglioli, Maria de Fátima Lobato da Cunha Sauma, Claiton Viegas Brenol, Geraldo da Rocha Castelar Pinheiro
Rheumatoid arthritis (RA) is a common autoimmune systemic inflammatory disease. In addition to joint involvement, RA patients frequently have other comorbidities, such as cardiovascular diseases. Drugs used for RA treatment may increase or decrease the risk of a cardiovascular event. This study aims to analyze cardiovascular risk comorbidities in patients with RA and the correlation with the use o...... hiện toàn bộ
Clinical characteristics and risk factors for gout flare during the postsurgical period
Advances in Rheumatology - Tập 59 Số 1 - 2019
Hyemin Jeong, Chan Hong Jeon
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