n−3 Fatty acids ameliorate hepatic steatosis and dysfunction after LXR agonist ingestion in mice
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids - Tập 1811 - Trang 491-497 - 2011
Tài liệu tham khảo
Browning, 2004, Molecular mediators of hepatic steatosis and liver injury, J. Clin. Invest., 114, 147, 10.1172/JCI200422422
Den Boer, 2004, Hepatic steatosis: a mediator of the metabolic syndrome. Lessons from animal models, Arterioscler. Thromb. Vasc. Biol., 24, 644, 10.1161/01.ATV.0000116217.57583.6e
Schultz, 2000, Role of LXRs in control of lipogenesis, Genes Dev., 14, 2831, 10.1101/gad.850400
Repa, 2000, Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers, Science, 289, 1524, 10.1126/science.289.5484.1524
Repa, 2002, Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta, J. Biol. Chem., 277, 18793, 10.1074/jbc.M109927200
Peet, 1998, Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha, Cell, 93, 693, 10.1016/S0092-8674(00)81432-4
Zaghini, 2002, Sterol regulatory element-binding protein-1c is responsible for cholesterol regulation of ileal bile acid-binding protein gene in vivo. Possible involvement of liver-X-receptor, J. Biol. Chem., 277, 1324, 10.1074/jbc.M106375200
Davis, 2001, 2000 George Lyman Duff Memorial Lecture: Atherosclerosis is a liver disease of the heart, Arterioscler. Thromb. Vasc. Biol., 21, 887, 10.1161/01.ATV.21.6.887
Terasaka, 2003, T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice, FEBS Lett., 536, 6, 10.1016/S0014-5793(02)03578-0
Grefhorst, 2002, Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles, J. Biol. Chem., 277, 34182, 10.1074/jbc.M204887200
Oosterveer, 2009, High fat feeding induces hepatic fatty acid elongation in mice, PLoS One, 4, e6066, 10.1371/journal.pone.0006066
Lin, 2005, Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP, Cell, 120, 261, 10.1016/j.cell.2004.11.043
Fraulob, 2010, A mouse model of metabolic syndrome: insulin resistance, fatty liver and non-alcoholic fatty pancreas disease (NAFPD) in C57BL/6 mice fed a high fat diet, Clin. Biochem. Nutr., 46, 212, 10.3164/jcbn.09-83
McKenney, 2007, Role of prescription omega-3 fatty acids in the treatment of hypertriglyceridemia, Pharmacotherapy, 27, 715, 10.1592/phco.27.5.715
Rustan, 1988, Eicosapentaenoic acid reduces hepatic synthesis and secretion of triacylglycerol by decreasing the activity of acyl-coenzyme A:1,2-diacylglycerol acyltransferase, J. Lipid Res., 29, 1417, 10.1016/S0022-2275(20)38418-2
Ou, 2001, Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR, Proc. Natl Acad. Sci. U. S. A., 98, 6027, 10.1073/pnas.111138698
Halminski, 1991, Differential effects of fish oil, safflower oil and palm oil on fatty acid oxidation and glycerolipid synthesis in rat liver, J. Nutr., 121, 1554, 10.1093/jn/121.10.1554
Worgall, 1998, Polyunsaturated fatty acids decrease expression of promoters with sterol regulatory elements by decreasing levels of mature sterol regulatory element-binding protein, J. Biol. Chem., 273, 25537, 10.1074/jbc.273.40.25537
Svegliati-Baroni, 2006, A model of insulin resistance and nonalcoholic steatohepatitis in rats: role of peroxisome proliferator-activated receptor-alpha and n−3 polyunsaturated fatty acid treatment on liver injury, Am. J. Pathol., 169, 846, 10.2353/ajpath.2006.050953
Capanni, 2006, Prolonged n−3 polyunsaturated fatty acid supplementation ameliorates hepatic steatosis in patients with non-alcoholic fatty liver disease: a pilot study, Aliment. Pharmacol. Ther., 23, 1143, 10.1111/j.1365-2036.2006.02885.x
Marsman, 2011, Reversal of hepatic steatosis by omega-3 fatty acids measured non-invasively by (1) H-magnetic resonance spectroscopy in a rat model, J. Gastroenterol. Hepatol., 26, 356, 10.1111/j.1440-1746.2010.06326.x
Tanaka, 2010, Eicosapentaenoic acid improves hepatic steatosis independent of PPARα activation through inhibition of SREBP-1 maturation in mice, Biochem. Pharmacol., 80, 1601, 10.1016/j.bcp.2010.07.031
Chang, 2009, n−3 fatty acids reduce arterial LDL-cholesterol delivery and arterial lipoprotein lipase levels and lipase distribution, Arterioscler. Thromb. Vasc. Biol., 29, 555, 10.1161/ATVBAHA.108.182287
Qi, 2002, Omega-3 triglycerides modify blood clearance and tissue targeting pathways of lipid emulsions, Biochemistry, 41, 3119, 10.1021/bi015770h
Folch, 1957, A simple method for isolation and purification of total lipids from animal tissues, J. Biol. Chem., 226, 497, 10.1016/S0021-9258(18)64849-5
Carr, 1957, Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts, Clin. Biochem., 26, 39, 10.1016/0009-9120(93)90015-X
Masson, 2004, Cholesteryl ester transfer protein modulates the effect of liver X receptor agonists on cholesterol transport and excretion in the mouse, J. Lipid Res., 45, 543, 10.1194/jlr.M300432-JLR200
Basciano, 2009, LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins, Am. J. Physiol. Gastrointest. Liver Physiol., 297, G323, 10.1152/ajpgi.90546.2008
Costet, 2000, Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor, J. Biol. Chem., 275, 28240, 10.1074/jbc.M003337200
Venkateswaran, 2000, Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha, Proc. Natl Acad. Sci. U. S. A., 97, 12097, 10.1073/pnas.200367697
Joseph, 2003, Reciprocal regulation of inflammation and lipid metabolism by liver X receptors, Nat. Med., 9, 213, 10.1038/nm820
Joseph, 2004, LXR-dependent gene expression is important for macrophage survival and the innate immune response, Cell, 119, 299, 10.1016/j.cell.2004.09.032
Gonzalez, 2009, Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR, Immunity, 31, 245, 10.1016/j.immuni.2009.06.018
Yu, 2003, Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8, J. Biol. Chem., 278, 15565, 10.1074/jbc.M301311200
Chang, 2010, n−3 Fatty acids decrease arterial low-density lipoprotein cholesterol delivery and lipoprotein lipase levels in insulin-resistant mice, Arterioscler. Thromb. Vasc. Biol., 30, 2510, 10.1161/ATVBAHA.110.215848
Tanaka, 2008, Highly purified eicosapentaenoic acid treatment improves nonalcoholic steatohepatitis, J. Clin. Gastroenterol., 42, 413, 10.1097/MCG.0b013e31815591aa
Loffler, 2006, Blood glucose-lowering nuclear receptor agonists only partially normalize hepatic gene expression in db/db mice, J. Pharmacol. Exp. Ther., 316, 797, 10.1124/jpet.105.093831
Araya, 2004, Increase in long-chain polyunsaturated fatty acid n−6/n−3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease, Clin. Sci. (Lond.), 106, 635, 10.1042/CS20030326
Sekiya, 2003, Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression, Hepatology, 38, 1529, 10.1016/j.hep.2003.09.028
Spadaro, 2008, Effects of n−3 polyunsaturated fatty acids in subjects with nonalcoholic fatty liver disease, Dig. Liver Dis., 40, 194, 10.1016/j.dld.2007.10.003
Musso, 2003, Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis, Hepatology, 37, 909, 10.1053/jhep.2003.50132
Joseph, 2002, Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors, J. Biol. Chem., 277, 11019, 10.1074/jbc.M111041200
Chisholm, 2003, The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse, J. Lipid Res., 44, 2039, 10.1194/jlr.M300135-JLR200
Jump, 2005, Fatty acid regulation of hepatic gene transcription, J. Nutr., 135, 2503, 10.1093/jn/135.11.2503
Field, 2002, Polyunsaturated fatty acids decrease the expression of sterol regulatory element-binding protein-1 in CaCo-2 cells: effect on fatty acid synthesis and triacylglycerol transport, Biochem. J., 15, 855, 10.1042/bj20020731
Jump, 1999, Regulation of gene expression by dietary fat, Annu. Rev. Nutr., 19, 63, 10.1146/annurev.nutr.19.1.63
Salati, 1986, Fatty acid inhibition of hormonal induction of acetyl-Co enzyme A carboxylase in hepatocyte monolayers, Arch. Biochem. Biophys., 246, 82, 10.1016/0003-9861(86)90451-0
Deng, 2004, Dietary olive oil and menhaden oil mitigate induction of lipogenesis in hyperinsulinemic corpulent JCR:LA-cp rats: microarray analysis of lipid-related gene expression, Endocrinology, 145, 5847, 10.1210/en.2004-0371
Pawar, 2003, The role of liver X receptor-alpha in the fatty acid regulation of hepatic gene expression, J. Biol. Chem., 278, 40736, 10.1074/jbc.M307973200
Deng, 2004, Dietary olive oil and menhaden oil mitigate induction of lipogenesis in hyperinsulinemic corpulent JCR:LA-cp rats: microarray analysis of lipid-related gene expression, Endocrinology, 145, 5847, 10.1210/en.2004-0371
Postic, 2007, ChREBP, a transcriptional regulator of glucose and lipid metabolism, Annu. Rev. Nutr., 27, 179, 10.1146/annurev.nutr.27.061406.093618
Cha, 2007, The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR, J. Biol. Chem., 282, 743, 10.1074/jbc.M605023200
Dentin, 2005, Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation, J. Clin. Invest., 115, 2843, 10.1172/JCI25256
Sampath, 2004, Polyunsaturated fatty acid regulation of gene expression, Nutr. Rev., 62, 333, 10.1111/j.1753-4887.2004.tb00058.x
Ide, 2003, Cross-talk between peroxisome peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling, Mol. Endocrinol., 17, 1255, 10.1210/me.2002-0191
Yoshikawa, 2003, Mol. Endocrinol., 17, 1240, 10.1210/me.2002-0190