miR-33: A Metabolic Conundrum

Bartel, 2018, Metazoan microRNAs, Cell, 173, 20, 10.1016/j.cell.2018.03.006 Rottiers, 2012, MicroRNAs in metabolism and metabolic disorders, Nat. Rev. Mol. Cell Biol., 13, 239, 10.1038/nrm3313 Aryal, 2017, MicroRNAs and lipid metabolism, Curr. Opin. Lipidol., 28, 273, 10.1097/MOL.0000000000000420 Goedeke, 2014, Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice, EMBO Mol. Med., 6, 1133, 10.15252/emmm.201404046 Horie, 2013, MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice, Nat. Commun., 4, 10.1038/ncomms3883 Price, 2018, Genetic ablation of miR-33 increases food intake, enhances adipose tissue expansion, and promotes obesity and insulin resistance, Cell Rep., 22, 2133, 10.1016/j.celrep.2018.01.074 Price, 2017, Genetic dissection of the impact of miR-33a and miR-33b during the progression of atherosclerosis, Cell Rep., 21, 1317, 10.1016/j.celrep.2017.10.023 Rayner, 2011, Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides, Nature, 478, 404, 10.1038/nature10486 Rottiers, 2013, Pharmacological inhibition of a microRNA family in nonhuman primates by a seed-targeting 8-mer antimiR, Sci. Transl. Med., 5, 10.1126/scitranslmed.3006840