miR-141 regulates TGF-β1-induced epithelial-mesenchymal transition through repression of HIPK2 expression in renal tubular epithelial cells
Tóm tắt
Từ khóa
Tài liệu tham khảo
Liu, 2004, Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention, J Am Soc Nephrol, 15, 1, 10.1097/01.ASN.0000106015.29070.E7
Zeisberg, 2004, The role of epithelial-to-mesenchymal transition in renal fibrosis, J Mol Med (Berl), 82, 175, 10.1007/s00109-003-0517-9
Kalluri, 2009, The basics of epithelial-mesenchymal transition, J Clin Invest, 119, 1420, 10.1172/JCI39104
Strutz, 1995, Identification and characterization of a fibroblast marker: FSP1, J Cell Biol, 130, 393, 10.1083/jcb.130.2.393
Strutz, 2006, Renal fibrosis and the origin of the renal fibroblast, Nephrol Dial Transplant, 21, 3368, 10.1093/ndt/gfl199
Liu, 2010, New insights into epithelial-mesenchymal transition in kidney fibrosis, J Am Soc Nephrol, 21, 212, 10.1681/ASN.2008121226
Li, 2007, Tubular epithelial cell dedifferentiation is driven by the helix-loop-helix transcriptional inhibitor id1, J Am Soc Nephrol, 18, 449, 10.1681/ASN.2006030236
Tan, 2006, Downregulation of SnoN expression in obstructive nephropathy is mediated by an enhanced ubiquitin-dependent degradation, J Am Soc Nephrol, 17, 2781, 10.1681/ASN.2005101055
Yang, 2002, Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy, J Clin Invest, 110, 1525, 10.1172/JCI0216219
Yang, 2003, Downregulation of smad transcriptional corepressors snon and ski in the fibrotic kidney: an amplification mechanism for TGF-beta1 signaling, J Am Soc Nephrol, 14, 3167, 10.1097/01.ASN.0000099373.33259.B2
Lan, 2011, Diverse roles of TGF-beta/smads in renal fibrosis and inflammation, Int J Biol Sci, 7, 1056, 10.7150/ijbs.7.1056
Meng, 2013, Role of the TGF-beta/BMP-7/smad pathways in renal diseases, Clin Sci (Lond), 124, 243, 10.1042/CS20120252
Kalluri, 2003, Epithelial-mesenchymal transition and its implications for fibrosis, J Clin Invest, 112, 1776, 10.1172/JCI200320530
Patel, 2012, MicroRNAs and fibrosis, Curr Opin Nephrol Hypertens, 21, 410, 10.1097/MNH.0b013e328354e559
Bartel, 2004, MicroRNAs: genomics, biogenesis, mechanism, and function, Cell, 116, 281, 10.1016/S0092-8674(04)00045-5
Wienholds, 2005, MicroRNA expression in zebrafish embryonic development, Science, 309, 310, 10.1126/science.1114519
Yi, 2006, Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs, Nat Genet, 38, 356, 10.1038/ng1744
Esquela-Kerscher, 2006, Oncomirs - microRNAs with a role in cancer. Nat Rev, Cancer, 6, 259
Zarjou, 2011, Identification of a microRNA signature in renal fibrosis: role of miR-21, Am J Physiol Renal Physiol, 301, F793, 10.1152/ajprenal.00273.2011
Xiong, 2012, The miR-200 family regulates TGF-beta1-induced renal tubular epithelial to mesenchymal transition through smad pathway by targeting ZEB1 and ZEB2 expression, Am J Physiol Renal Physiol, 302, F369, 10.1152/ajprenal.00268.2011
Wang, 2012, Suppression of microRNA-29 expression by TGF-beta1 promotes collagen expression and renal fibrosis, J Am Soc Nephrol, 23, 252, 10.1681/ASN.2011010055
Korpal, 2008, The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2, J Biol Chem, 283, 14910, 10.1074/jbc.C800074200
Calzado, 2007, HIPK2: a versatile switchboard regulating the transcription machinery and cell death, Cell Cycle, 6, 139, 10.4161/cc.6.2.3788
Lee, 2009, Hipk is an essential protein that promotes notch signal transduction in the drosophila eye by inhibition of the global co-repressor groucho, Dev Biol, 325, 263, 10.1016/j.ydbio.2008.10.029
Lee, 2009, Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of beta-catenin/Arm and stimulation of target gene expression, Development, 136, 241, 10.1242/dev.025460
Zhang, 2007, Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons, Nat Neurosci, 10, 77, 10.1038/nn1816
D’Orazi, 2002, Homeodomain-interacting protein kinase-2 phosphorylates p53 at ser 46 and mediates apoptosis, Nat Cell Biol, 4, 11, 10.1038/ncb714
Hofmann, 2002, Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2, Nat Cell Biol, 4, 1, 10.1038/ncb715
Rinaldo, 2007, HIPK2: a multitalented partner for transcription factors in DNA damage response and development, Biochem Cell Biol, 85, 411, 10.1139/O07-071
Jin, 2012, A systems approach identifies HIPK2 as a key regulator of kidney fibrosis, Nat Med, 18, 580, 10.1038/nm.2685
Ricci, 2013, Homeodomain-interacting protein kinase2 in human idiopathic pulmonary fibrosis, J Cell Physiol, 228, 235, 10.1002/jcp.24129
Wang, 2011, miR-200a prevents renal fibrogenesis through repression of TGF-beta2 expression, Diabetes, 60, 280, 10.2337/db10-0892
Tamagawa, 2014, Role of miR-200c/mir-141 in the regulation of epithelial-mesenchymal transition and migration in head and neck squamous cell carcinoma, Int J Mol Med, 33, 879, 10.3892/ijmm.2014.1625
Wynn, 2011, Integrating mechanisms of pulmonary fibrosis, J Exp Med, 208, 1339, 10.1084/jem.20110551
Yang, 2001, Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis, Am J Pathol, 159, 1465, 10.1016/S0002-9440(10)62533-3
Gregory, 2008, The mir-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1, Nat Cell Biol, 10, 593, 10.1038/ncb1722
Hill, 2000, The renal expression of transforming growth factor-beta isoforms and their receptors in acute and chronic experimental diabetes in rats, Endocrinology, 141, 1196, 10.1210/endo.141.3.7359
Chalazonitis, 2011, Homeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling, J Neurosci, 31, 13746, 10.1523/JNEUROSCI.1078-11.2011
Harada, 2003, Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation, J Biol Chem, 278, 38998, 10.1074/jbc.M307112200
Hofmann, 2003, HIPK2 regulates transforming growth factor-beta-induced c-jun NH (2)-terminal kinase activation and apoptosis in human hepatoma cells, Cancer Res, 63, 8271