lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3′ UTRs via Alu elements

Gong, C., Kim, Y. K., Woeller, C. F., Tang, Y. & Maquat, L. E. SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs. Genes Dev. 23, 54–66 (2009)

Kim, Y. K. et al. Staufen1 regulates diverse classes of mammalian transcripts. EMBO J. 26, 2670–2681 (2007)

Cordaux, R. & Batzer, M. A. The impact of retrotransposons on human genome evolution. Nature Rev. Genet. 10, 691–703 (2009)

Wilusz, J. E., Sunwoo, H. & Spector, D. L. Long noncoding RNAs: functional surprises from the RNA world. Genes Dev. 23, 1494–1504 (2009)

Walters, R. D., Kugel, J. F. & Goodrich, J. A. InvAluable junk: the cellular impact and function of Alu and B2 RNAs. IUBMB Life 61, 831–837 (2009)

Zuker, M. Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res. 31, 3406–3415 (2003)

Yulug, I. G., Yulug, A. & Fisher, E. M. The frequency and position of Alu repeats in cDNAs, as determined by database searching. Genomics 27, 544–548 (1995)

Batzer, M. A. & Deininger, P. L. Alu repeats and human genomic diversity. Nature Rev. Genet. 3, 370–379 (2002)

Hasler, J. & Strub, K. Alu elements as regulators of gene expression. Nucleic Acids Res. 34, 5491–5497 (2006)

Chen, L. L., DeCerbo, J. N. & Carmichael, G. G. Alu element-mediated gene silencing. EMBO J. 27, 1694–1705 (2008)

Pang, K. C. et al. RNAdb 2.0—an expanded database of mammalian non-coding RNAs. Nucleic Acids Res. 35, D178–D182 (2007)

Engström, P. G. et al. Complex loci in human and mouse genomes. PLoS Genet. 2, e47 (2006)

Kim, Y. K., Furic, L., Desgroseillers, L. & Maquat, L. E. Mammalian Staufen1 recruits Upf1 to specific mRNA 3′UTRs so as to elicit mRNA decay. Cell 120, 195–208 (2005)

Kim, H. H. et al. HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev. 23, 1743–1748 (2009)

Kuwano, Y. et al. NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motif. Nucleic Acids Res. 38, 225–238 (2010)

Ashley, C. T., Jr, Wilkinson, K. D., Reines, D. & Warren, S. T. FMR1 protein: conserved RNP family domains and selective RNA binding. Science 262, 563–566 (1993)

Bartel, D. P. MicroRNAs: target recognition and regulatory functions. Cell 136, 215–233 (2009)

Kapranov, P., Willingham, A. T. & Gingeras, T. R. Genome-wide transcription and the implications for genomic organization. Nature Rev. Genet. 8, 413–423 (2007)

Mathews, D. H., Sabina, J., Zuker, M. & Turner, D. H. Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. J. Mol. Biol. 288, 911–940 (1999)

Xia, T. et al. Thermodynamic parameters for an expanded nearest-neighbor model for formation of RNA duplexes with Watson–Crick base pairs. Biochemistry 37, 14719–14735 (1998)

Liang, C. C., Park, A. Y. & Guan, J. L. In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro . Nature Protocols 2, 329–333 (2007)

Providence, K. M. et al. SERPINE1 (PAI-1) is deposited into keratinocyte migration ‘trails’ and required for optimal monolayer wound repair. Arch. Dermatol. Res. 300, 303–310 (2008)

Marion, R. M., Fortes, P., Beloso, A., Dotti, C. & Ortin, J. A human sequence homologue of Staufen is an RNA-binding protein that is associated with polysomes and localizes to the rough endoplasmic reticulum. Mol. Cell. Biol. 19, 2212–2219 (1999)