lncRNA NEAT1 Binds to MiR-339-5p to Increase HOXA1 and Alleviate Ischemic Brain Damage in Neonatal Mice

Molecular Therapy - Nucleic Acids - Tập 20 - Trang 117-127 - 2020
Jing Zhao1, Ling He1, Lingling Yin1
1Department of Neonatology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, P.R. China

Tài liệu tham khảo

Rocha-Ferreira, 2015, Antimicrobial peptides and complement in neonatal hypoxia-ischemia induced brain damage, Front. Immunol., 6, 56, 10.3389/fimmu.2015.00056 Thornton, 2012, Molecular mechanisms of neonatal brain injury, Neurol. Res. Int., 2012, 506320, 10.1155/2012/506320 Wu, 2015, Neuroprotective agents for neonatal hypoxic-ischemic brain injury, Drug Discov. Today, 20, 1372, 10.1016/j.drudis.2015.09.001 Arteaga, 2017, Role of Antioxidants in Neonatal Hypoxic-Ischemic Brain Injury: New Therapeutic Approaches, Int. J. Mol. Sci., 18, e265, 10.3390/ijms18020265 Hagberg, 2015, The role of inflammation in perinatal brain injury, Nat. Rev. Neurol., 11, 192, 10.1038/nrneurol.2015.13 Chalak, 2012, Perinatal acidosis and hypoxic-ischemic encephalopathy in preterm infants of 33 to 35 weeks’ gestation, J. Pediatr., 160, 388, 10.1016/j.jpeds.2011.09.001 Higgins, 2011, Hypothermia and other treatment options for neonatal encephalopathy: an executive summary of the Eunice Kennedy Shriver NICHD workshop, J. Pediatr., 159, 851, 10.1016/j.jpeds.2011.08.004 Li, 2017, Brain-immune interactions in perinatal hypoxic-ischemic brain injury, Prog. Neurobiol., 159, 50, 10.1016/j.pneurobio.2017.10.006 Douglas-Escobar, 2015, Hypoxic-ischemic encephalopathy: a review for the clinician, JAMA Pediatr., 169, 397, 10.1001/jamapediatrics.2014.3269 Meloni, 2017, Pathophysiology and Neuroprotective Strategies in Hypoxic-Ischemic Brain Injury and Stroke, Brain Sci., 7, e110, 10.3390/brainsci7080110 Ponnusamy, 2019, The role of microRNAs in newborn brain development and hypoxic ischaemic encephalopathy, Neuropharmacology, 149, 55, 10.1016/j.neuropharm.2018.11.041 Cui, 2013, Analysis of microRNA expression detected by microarray of the cerebral cortex after hypoxic-ischemic brain injury, J. Craniofac. Surg., 24, 2147, 10.1097/SCS.0b013e3182a243f3 Ding, 2015, The role of miR-182 in regulating pineal CLOCK expression after hypoxia-ischemia brain injury in neonatal rats, Neurosci. Lett., 591, 75, 10.1016/j.neulet.2015.02.026 Long, 2014, MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects, J. Biol. Chem., 289, 5184, 10.1074/jbc.M113.518241 Zhang, 2018, Glycine-Histidine-Lysine (GHK) Alleviates Neuronal Apoptosis Due to Intracerebral Hemorrhage via the miR-339-5p/VEGFA Pathway, Front. Neurosci., 12, 644, 10.3389/fnins.2018.00644 Dhiraj, 2013, miRNAs-19b, -29b-2* and -339-5p show an early and sustained up-regulation in ischemic models of stroke, PLoS ONE, 8, e83717, 10.1371/journal.pone.0083717 Makki, 2011, Identification of novel Hoxa1 downstream targets regulating hindbrain, neural crest and inner ear development, Dev. Biol., 357, 295, 10.1016/j.ydbio.2011.06.042 Holland, 2005, The evolution of homeobox genes: Implications for the study of brain development, Brain Res. Bull., 66, 484, 10.1016/j.brainresbull.2005.06.003 Canu, 2009, HOXA1 A218G polymorphism is associated with smaller cerebellar volume in healthy humans, J. Neuroimaging, 19, 353, 10.1111/j.1552-6569.2008.00326.x Paraguison, 2007, Enhanced autophagic cell death in expanded polyhistidine variants of HOXA1 reduces PBX1-coupled transcriptional activity and inhibits neuronal differentiation, J. Neurosci. Res., 85, 479, 10.1002/jnr.21137 Roberts, 2014, The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease, Philos. Trans. R. Soc. Lond. B Biol. Sci., 369, 10.1098/rstb.2013.0507 Zhao, 2015, Microarray Profiling and Co-Expression Network Analysis of LncRNAs and mRNAs in Neonatal Rats Following Hypoxic-ischemic Brain Damage, Sci. Rep., 5, 13850, 10.1038/srep13850 Zhong, 2017, The long non-coding RNA Neat1 is an important mediator of the therapeutic effect of bexarotene on traumatic brain injury in mice, Brain Behav. Immun., 65, 183, 10.1016/j.bbi.2017.05.001 Das, 2014, lnCeDB: database of human long noncoding RNA acting as competing endogenous RNA, PLoS ONE, 9, e98965, 10.1371/journal.pone.0098965 Peng, 2010, [Expression of microRNA in neonatal rats with hypoxic-ischemic brain damage], Zhongguo Dang Dai Er Ke Za Zhi, 12, 373 Yang, 2013, Shenfu injection attenuates neonatal hypoxic-ischemic brain damage in rat, Neurol. Sci., 34, 1571, 10.1007/s10072-013-1288-x Ge, 2014, miR-21 improves the neurological outcome after traumatic brain injury in rats, Sci. Rep., 4, 6718, 10.1038/srep06718 Duan, 2018, MicroRNA-135b-5p prevents oxygen-glucose deprivation and reoxygenation-induced neuronal injury through regulation of the GSK-3β/Nrf2/ARE signaling pathway, Arch. Med. Sci., 14, 735, 10.5114/aoms.2017.71076 Liu, 2017, Role of microRNA-130a in myocardial hypoxia/reoxygenation injury, Exp. Ther. Med., 13, 759, 10.3892/etm.2016.3984 Liu, 2013, Effects of apoptosis-related proteins caspase-3, Bax and Bcl-2 on cerebral ischemia rats, Biomed. Rep., 1, 861, 10.3892/br.2013.153 Gong, 2017, Long Non-Coding RNA H19 Protects H9c2 Cells against Hypoxia-Induced Injury by Targeting MicroRNA-139, Cell. Physiol. Biochem., 44, 857, 10.1159/000485354 Zhao, 2015, miR-525-5p inhibits ADAMTS13 and is correlated with Ischemia/reperfusion injury-induced neuronal cell death, Int. J. Clin. Exp. Med., 8, 18115 Li, 2018, Suppression of microRNA-144-3p attenuates oxygen-glucose deprivation/reoxygenation-induced neuronal injury by promoting Brg1/Nrf2/ARE signaling, J. Biochem. Mol. Toxicol., 32, e22044, 10.1002/jbt.22044 Han, 2018, MicroRNA-577 inhibits the migration and invasion of hepatocellular carcinoma cells by targeting homeobox A1, Oncol. Rep., 39, 2987 Wang, 2015, MicroRNA-99a inhibits tumor aggressive phenotypes through regulating HOXA1 in breast cancer cells, Oncotarget, 6, 32737, 10.18632/oncotarget.5355 Kilicdag, 2014, Effects of caffeine on neuronal apoptosis in neonatal hypoxic-ischemic brain injury, J. Matern. Fetal Neonatal Med., 27, 1470, 10.3109/14767058.2013.878694 Yan, 2018, LncRNA NEAT1 promotes autophagy in MPTP-induced Parkinson’s disease through stabilizing PINK1 protein, Biochem. Biophys. Res. Commun., 496, 1019, 10.1016/j.bbrc.2017.12.149 Simchovitz, 2019, NEAT1 is overexpressed in Parkinson’s disease substantia nigra and confers drug-inducible neuroprotection from oxidative stress, FASEB J., 33, 11223, 10.1096/fj.201900830R Sunwoo, 2017, Altered Expression of the Long Noncoding RNA NEAT1 in Huntington’s Disease, Mol. Neurobiol., 54, 1577, 10.1007/s12035-016-9928-9 Zhou, 2019, LncRNA NEAT1 facilitates survival and angiogenesis in oxygen-glucose deprivation (OGD)-induced brain microvascular endothelial cells (BMECs) via targeting miR-377 and upregulating SIRT1, VEGFA, and BCL-XL, Brain Res., 1707, 90, 10.1016/j.brainres.2018.10.031 Makki, 2010, Hoxa1 lineage tracing indicates a direct role for Hoxa1 in the development of the inner ear, the heart, and the third rhombomere, Dev. Biol., 341, 499, 10.1016/j.ydbio.2010.02.014 Liu, 2016, Effects of microRNA-21 and microRNA-24 inhibitors on neuronal apoptosis in ischemic stroke, Am. J. Transl. Res., 8, 3179 Zhu, 2014, MicroRNA-124 (miR-124) regulates Ku70 expression and is correlated with neuronal death induced by ischemia/reperfusion, J. Mol. Neurosci., 52, 148, 10.1007/s12031-013-0155-9 Vinciguerra, 2014, MicroRNA-103-1 selectively downregulates brain NCX1 and its inhibition by anti-miRNA ameliorates stroke damage and neurological deficits, Mol. Ther., 22, 1829, 10.1038/mt.2014.113 Ayuk, 2016, The role of photobiomodulation on gene expression of cell adhesion molecules in diabetic wounded fibroblasts in vitro, J. Photochem. Photobiol. B, 161, 368, 10.1016/j.jphotobiol.2016.05.027